Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation
about
Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn.Clinical Features, Genetics and Potential Therapeutic Approaches for Birt-Hogg-Dubé Syndrome.Loss of Folliculin Disrupts Hematopoietic Stem Cell Quiescence and Homeostasis Resulting in Bone Marrow Failure.Mutation of Fnip1 is associated with B-cell deficiency, cardiomyopathy, and elevated AMPK activity.Molecular genetics and clinical features of Birt-Hogg-Dubé syndrome.The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissueBirt-Hogg-Dubé syndrome: Clinical and molecular aspects of recently identified kidney cancer syndrome.Control of B lymphocyte development and functions by the mTOR signaling pathways.FLCN: The causative gene for Birt-Hogg-Dubé syndrome.mTOR Pathways in Cancer and Autophagy.Hereditary kidney cancer syndromes: Genetic disorders driven by alterations in metabolism and epigenome regulation.H255Y and K508R missense mutations in tumour suppressor folliculin (FLCN) promote kidney cell proliferation.Splice-site mutation causing partial retention of intron in the FLCN gene in Birt-Hogg-Dubé syndrome: a case report.Loss of Fnip1 alters kidney developmental transcriptional program and synergizes with TSC1 loss to promote mTORC1 activation and renal cyst formation.
P2860
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P2860
Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Folliculin (Flcn) inactivation ...... hy through mTORC1 deregulation
@ast
Folliculin (Flcn) inactivation ...... hy through mTORC1 deregulation
@en
Folliculin
@nl
type
label
Folliculin (Flcn) inactivation ...... hy through mTORC1 deregulation
@ast
Folliculin (Flcn) inactivation ...... hy through mTORC1 deregulation
@en
Folliculin
@nl
prefLabel
Folliculin (Flcn) inactivation ...... hy through mTORC1 deregulation
@ast
Folliculin (Flcn) inactivation ...... hy through mTORC1 deregulation
@en
Folliculin
@nl
P2093
P2860
P50
P356
P1476
Folliculin (Flcn) inactivation ...... hy through mTORC1 deregulation
@en
P2093
Diana C Haines
Hisashi Hasumi
Hyoung-bin Oh
Kunio Nagashima
Laura S Schmidt
Rachel Reindorf
W Marston Linehan
Ying Huang
Yukiko Hasumi
P2860
P304
P356
10.1093/HMG/DDU286
P50
P577
2014-06-06T00:00:00Z