Metformin and phenformin activate AMP-activated protein kinase in the heart by increasing cytosolic AMP concentration
about
Metabolic actions of metformin in the heart can occur by AMPK-independent mechanismsAdenylate kinase and AMP signaling networks: metabolic monitoring, signal communication and body energy sensingTwo weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type miceResveratrol Reverses Functional Chagas Heart Disease in MiceTransitory activation of AMPK at reperfusion protects the ischaemic-reperfused rat myocardium against infarctionEffect of metformin on metabolic improvement and gut microbiotaFolliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulationCross regulation of sirtuin 1, AMPK, and PPARγ in conjugated linoleic acid treated adipocytes.Role of peroxisome proliferator-activated receptor {delta}/{beta} in hepatic metabolic regulation.Riluzole increases the rate of glucose transport in L6 myotubes and NSC-34 motor neuron-like cells via AMPK pathway activation.Extension of Drosophila lifespan by cinnamon through a sex-specific dependence on the insulin receptor substrate chicoMetformin activates AMP-activated protein kinase in primary human hepatocytes by decreasing cellular energy statusTargeting energy metabolic and oncogenic signaling pathways in triple-negative breast cancer by a novel adenosine monophosphate-activated protein kinase (AMPK) activatorAntileukemic effects of AMPK activators on BCR-ABL-expressing cells.Low density lipoprotein (LDL) receptor-related protein 6 (LRP6) regulates body fat and glucose homeostasis by modulating nutrient sensing pathways and mitochondrial energy expenditurePhenformin as prophylaxis and therapy in breast cancer xenograftsStructure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signalingThe role of PPARα in metformin-induced attenuation of mitochondrial dysfunction in acute cardiac ischemia/reperfusion in ratsMetabolomic fingerprint reveals that metformin impairs one-carbon metabolism in a manner similar to the antifolate class of chemotherapy drugs.Defining the molecular nexus of cancer, type 2 diabetes and cardiovascular disease.AMPK: Lessons from transgenic and knockout animalsActivation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failureAMP-activated protein kinase pathway: a potential therapeutic target in cardiometabolic disease.Direct inhibition of hexokinase activity by metformin at least partially impairs glucose metabolism and tumor growth in experimental breast cancer.Crosstalk between AMPK activation and angiotensin II-induced hypertrophy in cardiomyocytes: the role of mitochondria.Re-evaluating the general(ized) roles of AMPK in cellular metabolism.Anticancer effects of metformin and its potential use as a therapeutic agent for breast cancer.Targeting adenosine receptors in the development of cardiovascular therapeutics.Metformin therapy in diabetes: the role of cardioprotection.AMP-activated protein kinase activators in diabetic ulcers: from animal studies to Phase II drugs under investigation.Metformin, an old drug, brings a new era to cancer therapyα-Lipoic acid as a triglyceride-lowering nutraceutical.Resveratrol-Induced AMP-Activated Protein Kinase Activation Is Cell-Type Dependent: Lessons from Basic Research for Clinical Application.Activation of AMPK reduces the co-transporter activity of NKCC1.New insights into antidiabetic drugs: Possible applications in cancer treatment.Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation.Generation of digital responses in stress sensors.Activation of AMPK improves inflammation and insulin resistance in adipose tissue and skeletal muscle from pregnant women.Does long-term metformin treatment increase cardiac lipoprotein lipase?Influence of metformin on GLUT1 gene and protein expression in rat streptozotocin diabetes mellitus model.
P2860
Q22241963-0D4A07C4-A03A-48BA-AEBF-0576937BDF4EQ24646027-48EF26CC-6F29-40DD-9AEF-3340FB01B07DQ28485110-A6CA6856-BB62-403C-810D-EFE5801F11D6Q28553008-5628C8DD-262F-431B-AAB6-91130A084975Q33867405-581CA222-21F4-4949-855F-8C6D77E923BCQ34261321-EC781522-1566-4FC6-9C30-6C7CA33D83E3Q34307302-68DBF1EA-6F4B-4669-B70A-ED148E34A145Q34479148-6F7336F9-F131-497B-A51C-70CC185AF4DAQ34488953-D28D06A6-A8FE-4720-ADD0-A5493D706A12Q34802341-944CB738-E6AF-4420-AAB8-A30FA39269A5Q35022902-A8B6A884-CFF4-4388-8243-962ED8671798Q35534198-2360BE81-8C62-4E64-9D79-F8DBACEBFB37Q35604324-0FFC05D2-B64A-4BA5-A245-6EFB6A886E16Q35608171-CADAA7E4-23B9-447E-9A24-8B1490AEE366Q35801830-FCF4F7C6-04C2-4E03-95C8-0DEF6582B303Q35832359-6E452237-185D-4EEE-B143-CF7E24154A9FQ36006981-482B3937-2EEB-48B8-9F9D-1A44FC36DA5AQ36097027-C835D040-D053-4260-8F7E-FE34DB3F3886Q36209145-657A2432-300B-4E08-B718-363AD1845733Q36251554-DB038CF2-5928-4ED5-A183-95C8FAB89370Q37153612-F1980130-40B8-480D-B764-6E03ACF12F30Q37259538-DC5D35D8-6F75-4164-BBD0-25CB4978DAF7Q37411713-7576E7CC-A8FF-43AF-951F-B1DE2FD9B326Q37530258-A606B16F-9E2A-4472-ADEE-019351855E60Q37694958-113CB51D-21E7-41ED-976A-026287781882Q37823690-E7FC7027-5129-46A2-82DB-12717FBC207AQ37889961-367DFA44-2EF9-437A-BEB5-0863E2409C6BQ37990558-56B39A77-6065-4A66-934C-BF157F522286Q38083008-BEA92E6E-DED8-41AD-AB1F-DB5B480B5351Q38214392-2BE61CDA-DAE5-429F-B4CB-A539A121DB41Q38393435-4D677EC2-403E-4AA4-934C-5EF977600F9BQ38559352-4DD33570-6D73-461B-8632-EA3C1262A4F2Q38679237-13EAD7FE-9305-4F94-9D20-BA4AA506F1B3Q39007844-D87C8943-F53C-4311-8A98-FD33E752893DQ39272833-15E3D371-9B08-4CF6-B5B4-304CAD4A07B8Q39697365-409CB7A6-A5C2-4556-B1EA-DEC6F93B2934Q39891714-28F0541D-884F-4AB9-A91B-A8A58EB5399BQ40981163-276A0312-97BD-42FD-AA19-4A2D8C628AE6Q41221005-3DA0B174-E7DA-4F9E-92A1-9EBC7D1A1C50Q43003301-560A8E8E-562C-447F-8186-80B996B89DE1
P2860
Metformin and phenformin activate AMP-activated protein kinase in the heart by increasing cytosolic AMP concentration
description
2007 nî lūn-bûn
@nan
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մարտին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Metformin and phenformin activ ...... ng cytosolic AMP concentration
@ast
Metformin and phenformin activ ...... ng cytosolic AMP concentration
@en
Metformin and phenformin activ ...... ng cytosolic AMP concentration
@en-gb
Metformin and phenformin activ ...... ng cytosolic AMP concentration
@nl
type
label
Metformin and phenformin activ ...... ng cytosolic AMP concentration
@ast
Metformin and phenformin activ ...... ng cytosolic AMP concentration
@en
Metformin and phenformin activ ...... ng cytosolic AMP concentration
@en-gb
Metformin and phenformin activ ...... ng cytosolic AMP concentration
@nl
prefLabel
Metformin and phenformin activ ...... ng cytosolic AMP concentration
@ast
Metformin and phenformin activ ...... ng cytosolic AMP concentration
@en
Metformin and phenformin activ ...... ng cytosolic AMP concentration
@en-gb
Metformin and phenformin activ ...... ng cytosolic AMP concentration
@nl
P2093
P2860
P3181
P1476
Metformin and phenformin activ ...... ng cytosolic AMP concentration
@en
P2093
P2860
P304
P3181
P356
10.1152/AJPHEART.00002.2007
P407
P577
2007-03-23T00:00:00Z