Conversion of A3 adenosine receptor agonists into selective antagonists by modification of the 5'-ribofuran-uronamide moiety

Conversion of A3 adenosine receptor agonists into selective antagonists by modification of the 5'-ribofuran-uronamide moiety

Item
http://www.wikidata.org/entity/Q34313641
Translocation of arrestin induced by human A(3) adenosine receptor ligands in an engineered cell line: comparison with G protein-dependent pathwaysDesign and synthesis of truncated 4'-thioadenosine derivatives as potent and selective A3 adenosine receptor antagonists.Functionalized congeners of A3 adenosine receptor-selective nucleosides containing a bicyclo[3.1.0]hexane ring system.Synthesis and Binding Affinity of Homologated Adenosine Analogues as A3 Adenosine Receptor Ligands.Medicinal chemistry of the A3 adenosine receptor: agonists, antagonists, and receptor engineering.Structure-activity relationships of truncated D- and l-4'-thioadenosine derivatives as species-independent A3 adenosine receptor antagonistsSelective A(3) adenosine receptor antagonists derived from nucleosides containing a bicyclo[3.1.0]hexane ring system.Synthesis of 2-chloro-N6-substituted-4'-thioadenosine-5'-N, N-dialkyluronamides as potent and selective A3 adenosine receptor antagonists.Nucleoside-derived antagonists to A3 adenosine receptors lower mouse intraocular pressure and act across species.The A3 adenosine receptor as multifaceted therapeutic target: pharmacology, medicinal chemistry, and in silico approaches.Design, synthesis, and anti-tumor activity of 4'-thionucleosides as potent and selective agonists at the human A3 adenosine receptor.Stereoselective synthesis of 1'-functionalized-4'-thionucleosides.Determination and validation of LJ-2698, a potent human A3 adenosine receptor antagonist, in rat plasma by liquid chromatography-tandem mass spectrometry and its application in pharmacokinetic study.A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy.
P2860

Conversion of A3 adenosine receptor agonists into selective antagonists by modification of the 5'-ribofuran-uronamide moiety

Item
http://www.wikidata.org/entity/Q34313641
description
2005 nî lūn-bûn
@nan
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Conversion of A3 adenosine rec ...... 5'-ribofuran-uronamide moiety
@ast
Conversion of A3 adenosine rec ...... 5'-ribofuran-uronamide moiety
@en
Conversion of A3 adenosine rec ...... 5'-ribofuran-uronamide moiety
@nl
type
label
Conversion of A3 adenosine rec ...... 5'-ribofuran-uronamide moiety
@ast
Conversion of A3 adenosine rec ...... 5'-ribofuran-uronamide moiety
@en
Conversion of A3 adenosine rec ...... 5'-ribofuran-uronamide moiety
@nl
prefLabel
Conversion of A3 adenosine rec ...... 5'-ribofuran-uronamide moiety
@ast
Conversion of A3 adenosine rec ...... 5'-ribofuran-uronamide moiety
@en
Conversion of A3 adenosine rec ...... 5'-ribofuran-uronamide moiety
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Conversion of A3 adenosine rec ...... 5'-ribofuran-uronamide moiety
@en
P2093
P2860
P304
P31
P356
10.1016/J.BMCL.2005.10.054
P407
P433
P478
P50
P577
P5875
P698
P932