Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition. - Test2 - elhamkhani - TriplyDB

Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition.

Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition.

http://www.wikidata.org/entity/Q34317368

about

Adenosine signaling promotes hematopoietic stem and progenitor cell emergence.Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes.Oceans of opportunity: exploring vertebrate hematopoiesis in zebrafish Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium.Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence.Development of hematopoietic stem and progenitor cells from human pluripotent stem cells.Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression Inductive interactions mediated by interplay of asymmetric signalling underlie development of adult haematopoietic stem cells.Interferon-α signaling promotes embryonic HSC maturation.Transmembrane protein 88: a Wnt regulatory protein that specifies cardiomyocyte development.Cross-talk between Notch and Hedgehog regulates hepatic stellate cell fate in mice.Dpp dependent Hematopoietic stem cells give rise to Hh dependent blood progenitors in larval lymph gland of Drosophila.Identification of novel genes and networks governing hematopoietic stem cell development Dpath software reveals hierarchical haemato-endothelial lineages of Etv2 progenitors based on single-cell transcriptome analysis.Erythro-myeloid progenitors: "definitive" hematopoiesis in the conceptus prior to the emergence of hematopoietic stem cells.Protein kinases and associated pathways in pluripotent state and lineage differentiation.Estrogen defines the dorsal-ventral limit of VEGF regulation to specify the location of the hemogenic endothelial niche.Complex regulation of HSC emergence by the Notch signaling pathway.Transforming growth factor-β1 regulates the nascent hematopoietic stem cell niche by promoting gluconeogenesis.Endothelial-to-hematopoietic transition: Notch-ing vessels into blood.Understanding the regulation of vertebrate hematopoiesis and blood disorders - big lessons from a small fish.Sox17-mediated maintenance of fetal intra-aortic hematopoietic cell clusters.Developing HSCs become Notch independent by the end of maturation in the AGM region.GLI2 inhibition abrogates human leukemia stem cell dormancy.Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity.Interferon gamma signaling positively regulates hematopoietic stem cell emergence.Overlapping Requirements for Tet2 and Tet3 in Normal Development and Hematopoietic Stem Cell Emergence.Accumulation of the Vitamin D Precursor Cholecalciferol Antagonizes Hedgehog Signaling to Impair Hemogenic Endothelium Formation.G Protein-Coupled Receptors at the Crossroad between Physiologic and Pathologic Angiogenesis: Old Paradigms and Emerging Concepts.IP3R-mediated Ca2+ signals govern hematopoietic and cardiac divergence of Flk1+ cells via the calcineurin-NFATc3-Etv2 pathway.Emerging Roles of MTG16 in Cell-Fate Control of Hematopoietic Stem Cells and Cancer.Inhibition of endothelial ERK signalling by Smad1/5 is essential for haematopoietic stem cell emergence.The Notch ligand DLL4 specifically marks human hematoendothelial progenitors and regulates their hematopoietic fate.

P2860

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P2860

Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition.

http://www.wikidata.org/entity/Q34317368

description

2012 nî lūn-bûn

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2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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PNAS.1214361110

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Proceedings of the National Academy of Sciences of the United States of America

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Signaling axis involving Hedge ...... l-to-hematopoietic transition.

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P2093

Alejandro De Los Angeles

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Colleen E Albacker

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Garrett C Heffner

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Il-ho Jang

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Leonard I Zon

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M William Lensch

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Michelle I Lin

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Natasha Arora

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Peter Geon Kim

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Sabine Loewer

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P2860

Ventral embryonic tissues and Hedgehog proteins induce early AGM hematopoietic stem cell development

Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis

Tie2Cre-mediated gene ablation defines the stem-cell leukemia gene (SCL/tal1)-dependent window during hematopoietic stem-cell development

Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL

SCL/tal-1-dependent process determines a competence to select the definitive hematopoietic lineage prior to endothelial differentiation

Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac

Runx1 function in hematopoiesis is required in cells that express Tek

Hedgehog signaling is essential for endothelial tube formation during vasculogenesis

The scl gene product is required for the generation of all hematopoietic lineages in the adult mouse

The molecular basis of vascular lumen formation in the developing mouse aorta

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E141-50

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110

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George Q. Daley

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2012-12-12T00:00:00Z

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233909450

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23236128

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