The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice.
about
Differential contribution of Puma and Noxa in dual regulation of p53-mediated apoptotic pathwaysPUMA regulates intestinal progenitor cell radiosensitivity and gastrointestinal syndromeGenotypic characteristics of resistant tumors to pre-operative ionizing radiation in rectal cancerInjury-associated reacquiring of intestinal stem cell functionInhibition of intestinal epithelial apoptosis improves survival in a murine model of radiation combined injuryBalancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?Inhibition by uridine but not thymidine of p53-dependent intestinal apoptosis initiated by 5-fluorouracil: evidence for the involvement of RNA perturbationA mitochondria-targeted inhibitor of cytochrome c peroxidase mitigates radiation-induced deathTumorigenesis in the multiple intestinal neoplasia mouse: redundancy of negative regulators and specificity of modifiersIntegral role of Noxa in p53-mediated apoptotic responseApoptotic regulation of epithelial cellular extrusionMorphological and pathologic changes of experimental chronic atrophic gastritis (CAG) and the regulating mechanism of protein expression in rats.Mouse models of p53 functions.Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines.Intestinal dysplasia induced by simian virus 40 T antigen is independent of p53.A new class of molecular targeted radioprotectors: GSK-3beta inhibitorsTransgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiation-induced activation during embryogenesis.Pathologies associated with the p53 response.Gut instincts: thoughts on intestinal epithelial stem cells.Somatic stem cells and the kinetics of mutagenesis and carcinogenesis.The influence of Trp53 in the dose response of radiation-induced apoptosis, DNA repair and genomic stability in murine haematopoietic cells.DNA damage in stem cells activates p21, inhibits p53, and induces symmetric self-renewing divisions.P53 status as a predictive biomarker for patients receiving neoadjuvant radiation-based treatment: a meta-analysis in rectal cancer.Krüppel-like factor 4 is a radioprotective factor for the intestine following γ-radiation-induced gut injury in mice.Growth factors protect intestinal stem cells from radiation-induced apoptosis by suppressing PUMA through the PI3K/AKT/p53 axis.mdm2 Is critical for inhibition of p53 during lymphopoiesis and the response to ionizing irradiation.Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21.Acetylation of mouse p53 at lysine 317 negatively regulates p53 apoptotic activities after DNA damageBRCA1 functions as a breast stem cell regulator.In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activationDistinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression.The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells.Epithelial apoptosis in mechanistically distinct methods of injury in the murine small intestineImmunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2.The relative contribution of pro-apoptotic p53-target genes in the triggering of apoptosis following DNA damage in vitro and in vivo.Stem cell plasticity. Plasticity of epithelial stem cells in tissue regenerationApoptosis and colorectal cancer.Multiple mechanisms of N-phosphonacetyl-L-aspartate resistance in human cell lines: carbamyl-P synthetase/aspartate transcarbamylase/dihydro-orotase gene amplification is frequent only when chromosome 2 is rearranged.bak deletion stimulates gastric epithelial proliferation and enhances Helicobacter felis-induced gastric atrophy and dysplasia in mice.Obesity and intestinal epithelial deletion of the insulin receptor, but not the IGF 1 receptor, affect radiation-induced apoptosis in colon.
P2860
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P2860
The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice.
description
1994 nî lūn-bûn
@nan
1994 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
The role of p53 in spontaneous ...... normal and p53-deficient mice.
@ast
The role of p53 in spontaneous ...... normal and p53-deficient mice.
@en
The role of p53 in spontaneous ...... normal and p53-deficient mice.
@nl
type
label
The role of p53 in spontaneous ...... normal and p53-deficient mice.
@ast
The role of p53 in spontaneous ...... normal and p53-deficient mice.
@en
The role of p53 in spontaneous ...... normal and p53-deficient mice.
@nl
prefLabel
The role of p53 in spontaneous ...... normal and p53-deficient mice.
@ast
The role of p53 in spontaneous ...... normal and p53-deficient mice.
@en
The role of p53 in spontaneous ...... normal and p53-deficient mice.
@nl
P2093
P1433
P1476
The role of p53 in spontaneous ...... normal and p53-deficient mice.
@en
P2093
Hickman JA
Merritt AJ
P304
P407
P577
1994-02-01T00:00:00Z