The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling.
about
SIRT2 regulates tumour hypoxia response by promoting HIF-1α hydroxylationSTAT3 inhibits the degradation of HIF-1alpha by pVHL-mediated ubiquitinationIdentification of an alternative mechanism of degradation of the hypoxia-inducible factor-1alphaNewly discovered angiogenesis inhibitors and their mechanisms of actionA HIF-independent mediator of transcriptional responses to oxygen deprivation in Caenorhabditis elegans.Prolyl hydroxylase-2 (PHD2) exerts tumor-suppressive activity in pancreatic cancerPrediction and analysis of protein hydroxyproline and hydroxylysinevon Hippel-Lindau gene disruption in mouse pancreatic progenitors and its consequences on endocrine differentiation in vivo: importance of HIF1-α and VEGF-A upregulationThe role of PHD2 mutations in the pathogenesis of erythrocytosis.Two-photon imaging of cellular activities in oxygen sensing tissues.Oxygen tension regulates pancreatic beta-cell differentiation through hypoxia-inducible factor 1alpha.The ING gene family in the regulation of cell growth and tumorigenesis.Involvement of net and Hif1alpha in distinct yet intricately linked hypoxia-induced signaling pathways.CaMKII Inhibitor KN-62 Blunts Tumor Response to Hypoxia by Inhibiting HIF-1α in Hepatoma Cells.Translational control of collagen prolyl 4-hydroxylase-alpha(I) gene expression under hypoxia.Oxygen Sensing, Cardiac Ischemia, HIF-1α and Some Emerging ConceptsSuppression of hypoxia-induced HIF-1alpha and of angiogenesis in endothelial cells by myo-inositol trispyrophosphate-treated erythrocytes.Hypoxia inducible factor-1alpha mediates protection of DL-3-n-butylphthalide in brain microvascular endothelial cells against oxygen glucose deprivation-induced injury.Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity.Ascorbic acid regulates osterix expression in osteoblasts by activation of prolyl hydroxylase and ubiquitination-mediated proteosomal degradation pathwayEffect of conjugated linoleic acid on inhibition of prolyl hydroxylase 1 in hearts of miceThe ternary complex factor net is downregulated by hypoxia and regulates hypoxia-responsive genes.Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 ORF50/Rta lytic switch protein functions as a tetramerFundulus as the premier teleost model in environmental biology: opportunities for new insights using genomics.Key Roles of Glutamine Pathways in Reprogramming the Cancer Metabolism.Transgenic system for conditional induction and rescue of chronic myocardial hibernation provides insights into genomic programs of hibernation.HIFing the brakes: therapeutic opportunities for treatment of human malignancies.PHDs overactivation during chronic hypoxia "desensitizes" HIFalpha and protects cells from necrosis.The role of hypoxia inducible factor-1 in cell metabolism--a possible target in cancer therapy.Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism.Hypoxia and the HIF-1 transcriptional pathway reorganize a neuronal circuit for oxygen-dependent behavior in Caenorhabditis elegans.Oxygen, a source of life and stress.Phosphatidylinositol 3-kinase pathway regulates hypoxia-inducible factor-1 to protect from intestinal injury during necrotizing enterocolitis.HIF-independent role of prolyl hydroxylases in the cellular response to amino acidsMatriptase activation and shedding through PDGF-D-mediated extracellular acidosis.Interferon-gamma induces prolyl hydroxylase (PHD)3 through a STAT1-dependent mechanism in human endothelial cellsTwo distinct roles for EGL-9 in the regulation of HIF-1-mediated gene expression in Caenorhabditis elegans.The impact of new research technologies on our understanding of environmental causes of disease: the concept of clinical vulnerability.HAF drives the switch of HIF-1α to HIF-2α by activating the NF-κB pathway, leading to malignant behavior of T24 bladder cancer cells.Angiogenesis in the atherosclerotic plaque.
P2860
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P2860
The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling.
description
2006 nî lūn-bûn
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2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling.
@ast
The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling.
@en
The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling.
@nl
type
label
The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling.
@ast
The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling.
@en
The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling.
@nl
prefLabel
The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling.
@ast
The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling.
@en
The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling.
@nl
P2860
P356
P1433
P1476
The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling.
@en
P2093
Amandine Ginouvès
Edurne Berra
P2860
P356
10.1038/SJ.EMBOR.7400598
P577
2006-01-01T00:00:00Z