The role of a clinically important mutation in the fold and RNA-binding properties of KH motifs
about
Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes.A mouse model of the human Fragile X syndrome I304N mutation.Structure and function of KH domains.Substitution of critical isoleucines in the KH domains of Drosophila fragile X protein results in partial loss-of-function phenotypes.FMRP RNA targets: identification and validation.A study of the ultrastructure of fragile-X-related proteinsDiscrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs.The translation of translational control by FMRP: therapeutic targets for FXS.Altered expression of the FMR1 splicing variants landscape in premutation carriers.Molecular dynamics simulations show how the FMRP Ile304Asn mutation destabilizes the KH2 domain structure and affects its function.
P2860
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P2860
The role of a clinically important mutation in the fold and RNA-binding properties of KH motifs
description
2003 nî lūn-bûn
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2003 թուականի Մարտին հրատարակուած գիտական յօդուած
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2003 թվականի մարտին հրատարակված գիտական հոդված
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2003年の論文
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2003年論文
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2003年論文
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2003年論文
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2003年論文
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2003年論文
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2003年论文
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name
The role of a clinically impor ...... inding properties of KH motifs
@ast
The role of a clinically impor ...... inding properties of KH motifs
@en
The role of a clinically impor ...... inding properties of KH motifs
@nl
type
label
The role of a clinically impor ...... inding properties of KH motifs
@ast
The role of a clinically impor ...... inding properties of KH motifs
@en
The role of a clinically impor ...... inding properties of KH motifs
@nl
prefLabel
The role of a clinically impor ...... inding properties of KH motifs
@ast
The role of a clinically impor ...... inding properties of KH motifs
@en
The role of a clinically impor ...... inding properties of KH motifs
@nl
P2860
P356
P1433
P1476
The role of a clinically impor ...... inding properties of KH motifs
@en
P2093
Andres Ramos
David Hollingworth
P2860
P304
P356
10.1261/RNA.2168503
P407
P577
2003-03-01T00:00:00Z