about
Neuroendocrine differentiation in prostate cancer: a mechanism of radioresistance and treatment failureP6981, An Arylstibonic Acid, Is a Novel Low Nanomolar Inhibitor of cAMP Response Element-Binding Protein Binding to DNACaV channels and cancer: canonical functions indicate benefits of repurposed drugs as cancer therapeuticsPDE5 inhibitor promotes melanin synthesis through the PKG pathway in B16 melanoma cellsp21-Activated kinase 4 promotes prostate cancer progression through CREBRegulation of Cancer Cell Responsiveness to Ionizing Radiation Treatment by Cyclic AMP Response Element Binding Nuclear Transcription Factor.mAPC-GibbsOS: an integrated approach for robust identification of gene regulatory networks.Isorhynchophylline, a Potent Plant Alkaloid, Induces Apoptotic and Anti-Metastatic Effects in Human Hepatocellular Carcinoma Cells through the Modulation of Diverse Cell Signaling Cascades.In silico identification of potential key regulatory factors in smoking-induced lung cancer.Acidic environment leads to ROS-induced MAPK signaling in cancer cells.ROR1 is expressed in human breast cancer and associated with enhanced tumor-cell growth.Novel Type of Prodrug Activation through a Long-Range O,N-Acyl Transfer: A Case of Water-Soluble CREB Inhibitor.Molecular recognition by the KIX domain and its role in gene regulation.Cardiac progenitor cell commitment is inhibited by nuclear Akt expression.Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREBDiscovery of a Potent Anti-tumor Agent through Regioselective Mono-N-acylation of 7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine.Functional cyclic AMP response element in the breast cancer resistance protein (BCRP/ABCG2) promoter modulates epidermal growth factor receptor pathway- or androgen withdrawal-mediated BCRP/ABCG2 transcription in human cancer cells.The chemistry and pharmacology of privileged pyrroloquinazolines.Artesunate suppresses tumor growth and induces apoptosis through the modulation of multiple oncogenic cascades in a chronic myeloid leukemia xenograft mouse model.CREB and leukemogenesis.Integrative network-based approach identifies key genetic elements in breast invasive carcinoma.Identification of a Potent Inhibitor of CREB-Mediated Gene Transcription with Efficacious in Vivo Anticancer Activity.Downregulation of microRNA-27b-3p enhances tamoxifen resistance in breast cancer by increasing NR5A2 and CREB1 expression.Extracting the Benefit of Nexrutine® for Cancer Prevention.Integrative analysis of gene and miRNA expression profiles with transcription factor-miRNA feed-forward loops identifies regulators in human cancers.E2F8 as a Novel Therapeutic Target for Lung CancerThe onco-embryonic antigen ROR1 is expressed by a variety of human cancers.Structure-activity relationship studies of naphthol AS-E and its derivatives as anticancer agents by inhibiting CREB-mediated gene transcriptionCyclic AMP responsive element-binding protein promotes renal cell carcinoma proliferation probably via the expression of spindle and kinetochore-associated protein 2.Identification, synthesis and evaluation of substituted benzofurazans as inhibitors of CREB-mediated gene transcription.Systemic Inhibition of CREB is Well-tolerated in vivo.GRK3 is a direct target of CREB activation and regulates neuroendocrine differentiation of prostate cancer cells.G-protein-coupled receptor 81 promotes a malignant phenotype in breast cancer through angiogenic factor secretion.Activation of ERK1/2 Causes Pazopanib Resistance via Downregulation of DUSP6 in Synovial Sarcoma Cells.Targeting CREB signalling in neurogenesis.Towards tailored therapy of glioblastoma multiforme.Progress in the discovery of small-molecule inhibitors of bromodomain--histone interactions.CREB signalling in neural stem/progenitor cells: recent developments and the implications for brain tumour biology.Targeting novel signaling pathways for resistant acute myeloid leukemia.Design, synthesis and biological evaluation of regioisomers of 666-15 as inhibitors of CREB-mediated gene transcription.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Targeting CREB for cancer therapy: friend or foe
@ast
Targeting CREB for cancer therapy: friend or foe
@en
Targeting CREB for cancer therapy: friend or foe
@nl
type
label
Targeting CREB for cancer therapy: friend or foe
@ast
Targeting CREB for cancer therapy: friend or foe
@en
Targeting CREB for cancer therapy: friend or foe
@nl
prefLabel
Targeting CREB for cancer therapy: friend or foe
@ast
Targeting CREB for cancer therapy: friend or foe
@en
Targeting CREB for cancer therapy: friend or foe
@nl
P2093
P2860
P1476
Targeting CREB for cancer therapy: friend or foe
@en
P2093
Alan Ikeda
Bingbing X Li
Bryan Mitton
Kathleen M Sakamoto
Xiangshu Xiao
P2860
P304
P356
10.2174/156800910791208535
P577
2010-06-01T00:00:00Z