Identification of a Potent Inhibitor of CREB-Mediated Gene Transcription with Efficacious in Vivo Anticancer Activity.

Identification of a Potent Inhibitor of CREB-Mediated Gene Transcription with Efficacious in Vivo Anticancer Activity.

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http://www.wikidata.org/entity/Q35825716
Control of CREB expression in tumors: from molecular mechanisms and signal transduction pathways to therapeutic targetActivation of PTHrP-cAMP-CREB1 signaling following p53 loss is essential for osteosarcoma initiation and maintenance.Systemic Inhibition of CREB is Well-tolerated in vivo.Design, synthesis and biological evaluation of regioisomers of 666-15 as inhibitors of CREB-mediated gene transcription.Towards Targeting PI3K-Dependent Regulation of Gene Expression in Brain CancerAngiopoietin-like 4 Mediates Colonic Inflammation by Regulating Chemokine Transcript Stability via Tristetraprolin.GPR68, a proton-sensing GPCR, mediates interaction of cancer associated fibroblasts and cancer cells.Linking CREB function with altered metabolism in murine fibroblast-based model cell lines.The high-production volume fungicide pyraclostrobin induces triglyceride accumulation associated with mitochondrial dysfunction, and promotes adipocyte differentiation independent of PPARγ activation, in 3T3-L1 cells.Anticancer Pyrroloquinazoline LBL1 Targets Nuclear Lamins.Design, synthesis and evaluation of antitumor acylated monoaminopyrroloquinazolines.ETS1 is associated with cisplatin resistance through IKKα/NF-κB pathway in cell line MDA-MB-231.PI3K Activation in Neural Stem Cells Drives Tumorigenesis which can be Ameliorated by Targeting the cAMP Response Element Binding (CREB) Protein.A Lamin-Binding Ligand Inhibits Homologous Recombination Repair of DNA Double-Strand BreaksPresenilin 1 deficiency suppresses autophagy in human neural stem cells through reducing γ-secretase-independent ERK/CREB signalingTolerance to sustained activation of the cAMP/Creb pathway activity in osteoblastic cells is enabled by loss of p53
P2860

Identification of a Potent Inhibitor of CREB-Mediated Gene Transcription with Efficacious in Vivo Anticancer Activity.

Item
http://www.wikidata.org/entity/Q35825716
description
2015 nî lūn-bûn
@nan
2015年の論文
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2015年論文
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2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Identification of a Potent Inh ...... s in Vivo Anticancer Activity.
@ast
Identification of a Potent Inh ...... s in Vivo Anticancer Activity.
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type
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Identification of a Potent Inh ...... s in Vivo Anticancer Activity.
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Identification of a Potent Inh ...... s in Vivo Anticancer Activity.
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prefLabel
Identification of a Potent Inh ...... s in Vivo Anticancer Activity.
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Identification of a Potent Inh ...... s in Vivo Anticancer Activity.
@en
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P1476
P2093
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Identification of a Potent Inh ...... s in Vivo Anticancer Activity.
@en
P2093
P2860
P304
P31
P356
10.1021/ACS.JMEDCHEM.5B00468
P407
P433
P478
P577
P5875
P698
P932