Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus. - Test2 - elhamkhani - TriplyDB

Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus.

Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus.

http://www.wikidata.org/entity/Q34388621

about

Molecular mechanisms of biological aging in intervertebral discs HIF-1α and growth plate development: what we really know Oxygen changes drive non-uniform scaling in Drosophila melanogaster embryogenesis.Defining the phenotype of young healthy nucleus pulposus cells: recommendations of the Spine Research Interest Group at the 2014 annual ORS meeting Understanding nucleus pulposus cell phenotype: a prerequisite for stem cell based therapies to treat intervertebral disc degeneration Nucleus pulposus phenotypic markers to determine stem cell differentiation: fact or fiction?Class I and IIa HDACs Mediate HIF-1α Stability Through PHD2-Dependent Mechanism, While HDAC6, a Class IIb Member, Promotes HIF-1α Transcriptional Activity in Nucleus Pulposus Cells of the Intervertebral Disc.Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signaling Notochord Cells in Intervertebral Disc Development and Degeneration Surgical anatomy, radiological features, and molecular biology of the lumbar intervertebral discs.Developmental mechanisms of intervertebral disc and vertebral column formation.Chronic inflammation triggered by the NLRP3 inflammasome in myeloid cells promotes growth plate dysplasia by mesenchymal cells.Circadian factors BMAL1 and RORα control HIF-1α transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health Formation, function, and exhaustion of notochordal cytoplasmic vacuoles within intervertebral disc: current understanding and speculation.Targeting the annulus fibrosus of the intervertebral disc: Col1a2-Cre(ER)T mice show specific activity of Cre recombinase in the outer annulus fibrosus.Fibrosis and hypoxia-inducible factor-1α-dependent tumors of the soft tissue on loss of von Hippel-Lindau in mesenchymal progenitors.Bicarbonate Recycling by HIF-1-Dependent Carbonic Anhydrase Isoforms 9 and 12 Is Critical in Maintaining Intracellular pH and Viability of Nucleus Pulposus Cells.LncRNA-RP11-296A18.3/miR-138/HIF1A Pathway Regulates the Proliferation ECM Synthesis of Human Nucleus Pulposus Cells (HNPCs).PHD3 is a transcriptional coactivator of HIF-1α in nucleus pulposus cells independent of the PKM2-JMJD5 axis.A novel mouse model of intervertebral disc degeneration shows altered cell fate and matrix homeostasis.Expression of Carbonic Anhydrase III, a Nucleus Pulposus Phenotypic Marker, is Hypoxia-responsive and Confers Protection from Oxidative Stress-induced Cell Death.

P2860

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P2860

Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus.

http://www.wikidata.org/entity/Q34388621

description

2014 nî lūn-bûn

@nan

2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2014 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

@zh-hk

2014年論文

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2014年論文

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2014年论文

@wuu

name

Loss of HIF-1α in the notochor ...... rance of the nucleus pulposus.

@ast

Loss of HIF-1α in the notochor ...... rance of the nucleus pulposus.

@en

Loss of HIF-1α in the notochor ...... rance of the nucleus pulposus.

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type

label

Loss of HIF-1α in the notochor ...... rance of the nucleus pulposus.

@ast

Loss of HIF-1α in the notochor ...... rance of the nucleus pulposus.

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Loss of HIF-1α in the notochor ...... rance of the nucleus pulposus.

@nl

prefLabel

Loss of HIF-1α in the notochor ...... rance of the nucleus pulposus.

@ast

Loss of HIF-1α in the notochor ...... rance of the nucleus pulposus.

@en

Loss of HIF-1α in the notochor ...... rance of the nucleus pulposus.

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JOURNAL.PONE.0110768

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Loss of HIF-1α in the notochor ...... arance of the nucleus pulposus

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Alexander Robling

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Amato J Giaccia

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Christophe Merceron

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Ernestina Schipani

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Irving M Shapiro

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Makarand V Risbud

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Tremika LeShan Wilson

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P2860

Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development

Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: implications for disk degeneration and chordoma formation

Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival

Impaired intervertebral disc development and premature disc degeneration in mice with notochord-specific deletion of CCN2

A global double-fluorescent Cre reporter mouse

A mouse line expressing Foxa2-driven Cre recombinase in node, notochord, floorplate, and endoderm.

Hedgehog signaling is required for formation of the notochord sheath and patterning of nuclei pulposi within the intervertebral discs.

Tracing notochord-derived cells using a Noto-cre mouse: implications for intervertebral disc development.

Nutrition of the intervertebral disc.

Hif-1alpha regulates differentiation of limb bud mesenchyme and joint development.

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e110768

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10

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Laura Mangiavini

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2014-10-22T00:00:00Z

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