Hif-1alpha regulates differentiation of limb bud mesenchyme and joint development. - Test2 - elhamkhani - TriplyDB

Hif-1alpha regulates differentiation of limb bud mesenchyme and joint development.

Hif-1alpha regulates differentiation of limb bud mesenchyme and joint development.

http://www.wikidata.org/entity/Q36119714

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Direct regulation of TWIST by HIF-1alpha promotes metastasis HIF-1α and growth plate development: what we really know Effects of exposure to a DNA damaging agent on the hypoxia inducible factors in organogenesis stage mouse limbs von Hippel-Lindau gene disruption in mouse pancreatic progenitors and its consequences on endocrine differentiation in vivo: importance of HIF1-α and VEGF-A upregulation JAWS coordinates chondrogenesis and synovial joint positioning Flavonoid Compound Icariin Activates Hypoxia Inducible Factor-1α in Chondrocytes and Promotes Articular Cartilage Repair Expression of carbonic anhydrase IX in human fetal joints, ligaments and tendons: a potential marker of mechanical stress in fetal development?Expression of transmembrane carbonic anhydrases, CAIX and CAXII, in human development.A central role for hypoxic signaling in cartilage, bone, and hematopoiesis.Oxygen tension regulates pancreatic beta-cell differentiation through hypoxia-inducible factor 1alpha.HIF1α and pancreatic β-cell development.Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage Analysis of Mouse Growth Plate Development.The role of oxygen availability in embryonic development and stem cell function Defining the earliest transcriptional steps of chondrogenic progenitor specification during the formation of the digits in the embryonic limb.Assessment of hypoxia inducible factor levels in cancer cell lines upon hypoxic induction using a novel reporter construct Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus.Icaritin, an exogenous phytomolecule, enhances osteogenesis but not angiogenesis--an in vitro efficacy study Hypoxia inhibits hypertrophic differentiation and endochondral ossification in explanted tibiae.Extracellular matrix genes as hypoxia-inducible targets.Hypoxia enhances differentiation of mouse embryonic stem cells into definitive endoderm and distal lung cells.Physical and functional interactions between Runx2 and HIF-1α induce vascular endothelial growth factor gene expression.New insights into endocrine pancreatic development: the role of environmental factors.Ascorbic acid regulates osterix expression in osteoblasts by activation of prolyl hydroxylase and ubiquitination-mediated proteosomal degradation pathway Thrombospondin-2 influences the proportion of cartilage and bone during fracture healing.HIF modulation of Wnt signaling regulates skeletal myogenesis in vivo.Runx2 protein stabilizes hypoxia-inducible factor-1α through competition with von Hippel-Lindau protein (pVHL) and stimulates angiogenesis in growth plate hypertrophic chondrocytes.Hypoxia-Inducible Factor 1 Is an Inductor of Transcription Factor Activating Protein 2 Epsilon Expression during Chondrogenic Differentiation.The HIF signaling pathway in osteoblasts directly modulates erythropoiesis through the production of EPO.Hypoxia-inducible factor-1 (HIF-1) but not HIF-2 is essential for hypoxic induction of collagen prolyl 4-hydroxylases in primary newborn mouse epiphyseal growth plate chondrocytes.Conditional Deletion of Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Gene Reveals Its Essential Role in Chondrocyte Function and Endochondral Bone Formation.Inhibition of Hif1α prevents both trauma-induced and genetic heterotopic ossification Gpr177, a novel locus for bone mineral density and osteoporosis, regulates osteogenesis and chondrogenesis in skeletal development Skeletal metamorphosis in fibrodysplasia ossificans progressiva (FOP)Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia.Interaction of HIF1α and β-catenin inhibits matrix metalloproteinase 13 expression and prevents cartilage damage in mice Role of hypoxia-inducible factor 1 alpha in the integrity of articular cartilage in murine knee joints Ultrasonographic Assessment of the Distal Femoral Cartilage Thickness in Patients with Homozygous Sickle Cell Disease.Sonic hedgehog signaling directly targets Hyaluronic Acid Synthase 2, an essential regulator of phalangeal joint patterning.Oxygen and Cell Fate Decisions.

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P2860

Hif-1alpha regulates differentiation of limb bud mesenchyme and joint development.

http://www.wikidata.org/entity/Q36119714

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

Hif-1alpha regulates differentiation of limb bud mesenchyme and joint development.

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Hif-1alpha regulates differentiation of limb bud mesenchyme and joint development.

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type

label

Hif-1alpha regulates differentiation of limb bud mesenchyme and joint development.

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Hif-1alpha regulates differentiation of limb bud mesenchyme and joint development.

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prefLabel

Hif-1alpha regulates differentiation of limb bud mesenchyme and joint development.

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Hif-1alpha regulates differentiation of limb bud mesenchyme and joint development.

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Journal of Cell Biology

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Hif-1alpha regulates differentiation of limb bud mesenchyme and joint development

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P2093

Amato J Giaccia

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Dawn Zinyk

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Ernestina Schipani

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Henry M Kronenberg

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Michael T Longaker

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Quynh Le

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Richa Kathri

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Yasemin Gunes

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P2860

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling

A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene

MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes

Genetic analysis of pathways regulated by the von Hippel-Lindau tumor suppressor in Caenorhabditis elegans

Targeting HIF-1 for cancer therapy

The biology of VEGF and its receptors

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

Loss of PTEN facilitates HIF-1-mediated gene expression

Wnt-14 plays a pivotal role in inducing synovial joint formation in the developing appendicular skeleton

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451-464

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10.1083/JCB.200612023

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3

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177

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Randall S. Johnson

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2007-04-30T00:00:00Z

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6358725

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17470636

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2064828

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