Molecular chlorine generated by the myeloperoxidase-hydrogen peroxide-chloride system of phagocytes converts low density lipoprotein cholesterol into a family of chlorinated sterols.
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Human macrophages limit oxidation products in low density lipoproteinIncreased atherosclerosis in myeloperoxidase-deficient miceHypochlorite modification of sphingomyelin generates chlorinated lipid species that induce apoptosis and proteome alterations in dopaminergic PC12 neurons in vitro.MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases.Effects of protein oxidation on the structure and stability of model discoidal high-density lipoproteinsReactive chlorinating species produced by myeloperoxidase target the vinyl ether bond of plasmalogens: identification of 2-chlorohexadecanal.Role of eosinophil peroxidase in the origins of protein oxidation in asthma.Linoleic acid hydroperoxide reacts with hypochlorous acid, generating peroxyl radical intermediates and singlet molecular oxygenNeutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps.Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein.Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean?Inflammation and cancer: chemical approaches to mechanisms, imaging, and treatment.Potent antioxidative activity of lycopene: A potential role in scavenging hypochlorous acidCholesterol, reactive oxygen species, and the formation of biologically active mediatorsLow-density lipoprotein modified by myeloperoxidase in inflammatory pathways and clinical studies.Chromatographic methods for the analyses of 2-halofatty aldehydes and chlorohydrin molecular species of lysophosphatidylcholine.Identification of lysophosphatidylcholine-chlorohydrin in human atherosclerotic lesions.2-Chlorohexadecanal and 2-chlorohexadecanoic acid induce COX-2 expression in human coronary artery endothelial cells.3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.A novel form of hereditary myeloperoxidase deficiency linked to endoplasmic reticulum/proteasome degradation.Chlorinated Phospholipids and Fatty Acids: (Patho)physiological Relevance, Potential Toxicity, and Analysis of Lipid ChlorohydrinsPotential for chlorine gas-induced injury in the extrapulmonary vasculature.Rapid and ratiometric detection of hypochlorite with real application in tap water: molecules to low cost devices (TLC sticks).Development of imidazoline-2-thiones based two-photon fluorescence probes for imaging hypochlorite generation in a co-culture system.Formation of chlorinated lipids post-chlorine gas exposure.Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase.Modulation of arachidonic and linoleic acid metabolites in myeloperoxidase-deficient mice during acute inflammation.Vitamin C protects against and reverses specific hypochlorous acid- and chloramine-dependent modifications of low-density lipoprotein.Reactive brominating species produced by myeloperoxidase target the vinyl ether bond of plasmalogens: disparate utilization of sodium halides in the production of alpha-halo fatty aldehydes.Eosinophil Peroxidase Catalyzed Protein Carbamylation Participates in Asthma.Lipid oxidation by hypochlorous acid: chlorinated lipids in atherosclerosis and myocardial ischemia.Purification and structure of the major product obtained by reaction of NADPH and NMNH with the myeloperoxidase/hydrogen peroxide/chloride system.Human neutrophils employ the myeloperoxidase/hydrogen peroxide/chloride system to oxidatively damage apolipoprotein A-I.Reactive chlorinating species produced during neutrophil activation target tissue plasmalogens: production of the chemoattractant, 2-chlorohexadecanal.Eosinophil peroxidase-derived reactive brominating species target the vinyl ether bond of plasmalogens generating a novel chemoattractant, alpha-bromo fatty aldehyde.Neutrophil-mediated accumulation of 2-ClHDA during myocardial infarction: 2-ClHDA-mediated myocardial injury.Fluorescent hydroxylamine derived from the fragmentation of PAMAM dendrimers for intracellular hypochlorite recognition.2-Chlorofatty acids induce Weibel-Palade body mobilization.Effects of exposure to water disinfection by-products in a swimming pool: A metabolome-wide association study.Stereoselective Construction of Halogenated Quaternary Carbon Centers by Brønsted Base Catalyzed [4+2] Cycloaddition of α-Haloaldehydes.
P2860
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P2860
Molecular chlorine generated by the myeloperoxidase-hydrogen peroxide-chloride system of phagocytes converts low density lipoprotein cholesterol into a family of chlorinated sterols.
description
1996 nî lūn-bûn
@nan
1996 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Molecular chlorine generated b ...... family of chlorinated sterols.
@ast
Molecular chlorine generated b ...... family of chlorinated sterols.
@en
Molecular chlorine generated b ...... family of chlorinated sterols.
@nl
type
label
Molecular chlorine generated b ...... family of chlorinated sterols.
@ast
Molecular chlorine generated b ...... family of chlorinated sterols.
@en
Molecular chlorine generated b ...... family of chlorinated sterols.
@nl
prefLabel
Molecular chlorine generated b ...... family of chlorinated sterols.
@ast
Molecular chlorine generated b ...... family of chlorinated sterols.
@en
Molecular chlorine generated b ...... family of chlorinated sterols.
@nl
P2093
P356
P1476
Molecular chlorine generated b ...... family of chlorinated sterols.
@en
P2093
P304
23080-23088
P356
10.1074/JBC.271.38.23080
P407
P577
1996-09-01T00:00:00Z