UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells. - Test2 - elhamkhani - TriplyDB

UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells.

UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells.

http://www.wikidata.org/entity/Q34401922

about

The epigenetic basis of diffuse large B-cell lymphoma Hijacked in cancer: the KMT2 (MLL) family of methyltransferases Histone methylation modifiers in cellular signaling pathways Transposon mutagenesis identifies genes and cellular processes driving epithelial-mesenchymal transition in hepatocellular carcinoma.Epigenetic control of the immune system: a lesson from Kabuki syndrome.Epigenetic regulation of epithelial-mesenchymal transition Whole-exome sequencing defines the mutational landscape of pheochromocytoma and identifies KMT2D as a recurrently mutated gene Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes.Coupling of T cell receptor specificity to natural killer T cell development by bivalent histone H3 methylation.Htt CAG repeat expansion confers pleiotropic gains of mutant huntingtin function in chromatin regulation.Epigenetic Role of Histone 3 Lysine Methyltransferase and Demethylase in Regulating Apoptosis Predicting the Recurrence of Atypical Meningioma G9a orchestrates PCL3 and KDM7A to promote histone H3K27 methylation.UTX inhibits EMT-induced breast CSC properties by epigenetic repression of EMT genes in cooperation with LSD1 and HDAC1.UTX inhibition as selective epigenetic therapy against TAL1-driven T-cell acute lymphoblastic leukemia An essential role for UTX in resolution and activation of bivalent promoters.Histone demethylases in physiology and cancer: a tale of two enzymes, JMJD3 and UTX.Stabilization of histone demethylase PHF8 by USP7 promotes breast carcinogenesis.Genomic and Epigenomic Alterations in Cancer Histone Demethylase KDM6A Controls the Mammary Luminal Lineage through Enzyme-Independent Mechanisms.Molecular pathways: deregulation of histone h3 lysine 27 methylation in cancer-different paths, same destination Targeting of cancer stem cells by inhibitors of DNA and histone methylation.JARID1D Is a Suppressor and Prognostic Marker of Prostate Cancer Invasion and Metastasis.VII. Are lymphomas driven by epigenetic lesions?CHARGE and Kabuki Syndromes: Gene-Specific DNA Methylation Signatures Identify Epigenetic Mechanisms Linking These Clinically Overlapping Conditions.Genome-wide ChIP-seq analysis of EZH2-mediated H3K27me3 target gene profile highlights differences between low- and high-grade astrocytic tumors.Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma PARP1 enhances lung adenocarcinoma metastasis by novel mechanisms independent of DNA repair.MLL3/MLL4/COMPASS Family on Epigenetic Regulation of Enhancer Function and Cancer.Enhancer deregulation in cancer and other diseases.Epigenetic balance of gene expression by Polycomb and COMPASS families.H3K27 Methylation: A Focal Point of Epigenetic Deregulation in Cancer.Histone demethylase KDM2A promotes tumor cell growth and migration in gastric cancer.Dysregulation of histone methyltransferases in breast cancer - Opportunities for new targeted therapies?Writing, erasing and reading histone lysine methylations.Histone H3 lysine 4 methyltransferase KMT2D.Orchestration of H3K27 methylation: mechanisms and therapeutic implication.Xist RNA repeat E is essential for ASH2L recruitment to the inactive X and regulates histone modifications and escape gene expression.KDM6A addiction of cervical carcinoma cell lines is triggered by E7 and mediated by p21CIP1 suppression of replication stress The H3K27me3-demethylase KDM6A is suppressed in breast cancer stem-like cells, and enables the resolution of bivalency during the mesenchymal-epithelial transition.UTX/KDM6A Loss Enhances the Malignant Phenotype of Multiple Myeloma and Sensitizes Cells to EZH2 inhibition.

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UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells.

http://www.wikidata.org/entity/Q34401922

description

2014 nî lūn-bûn

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2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2014 թվականի փետրվարին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

UTX and MLL4 coordinately regu ...... veness in breast cancer cells.

@ast

UTX and MLL4 coordinately regu ...... veness in breast cancer cells.

@en

UTX and MLL4 coordinately regu ...... veness in breast cancer cells.

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type

label

UTX and MLL4 coordinately regu ...... veness in breast cancer cells.

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UTX and MLL4 coordinately regu ...... veness in breast cancer cells.

@en

UTX and MLL4 coordinately regu ...... veness in breast cancer cells.

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prefLabel

UTX and MLL4 coordinately regu ...... veness in breast cancer cells.

@ast

UTX and MLL4 coordinately regu ...... veness in breast cancer cells.

@en

UTX and MLL4 coordinately regu ...... veness in breast cancer cells.

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UTX and MLL4 coordinately regu ...... veness in breast cancer cells.

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Amrish Sharma

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Bingnan Gu

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Hui-Kuan Lin

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Jae-Hwan Kim

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Min Gyu Lee

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Shilpa S Dhar

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Sung-Hun Lee

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P2860

PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex

LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer

Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth.

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

Combinatorial patterns of histone acetylations and methylations in the human genome

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

DAVID: Database for Annotation, Visualization, and Integrated Discovery

High-resolution profiling of histone methylations in the human genome

Role of transforming growth factor beta in human disease

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