Mutations in the DNA ligase I gene of an individual with immunodeficiencies and cellular hypersensitivity to DNA-damaging agents.
about
Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repairDNA ligase I is required for fetal liver erythropoiesis but is not essential for mammalian cell viabilityMammalian DNA ligase III: molecular cloning, chromosomal localization, and expression in spermatocytes undergoing meiotic recombinationDistinct kinetics of human DNA ligases I, IIIalpha, IIIbeta, and IV reveal direct DNA sensing ability and differential physiological functions in DNA repairActivation of mammalian DNA ligase I through phosphorylation by casein kinase IIThe N-terminal domain of human DNA ligase I contains the nuclear localization signal and directs the enzyme to sites of DNA replicationGerm line variation in nucleotide excision repair genes and lung cancer risk in smokersFunctional redundancy between DNA ligases I and III in DNA replication in vertebrate cellsA newly identified DNA ligase of Saccharomyces cerevisiae involved in RAD52-independent repair of DNA double-strand breaksAn interaction between the mammalian DNA repair protein XRCC1 and DNA ligase IIIEukaryotic DNA ligases: structural and functional insightsPartial complementation of a DNA ligase I deficiency by DNA ligase III and its impact on cell survival and telomere stability in mammalian cellsAn interaction between DNA ligase I and proliferating cell nuclear antigen: implications for Okazaki fragment synthesis and joiningRational design of human DNA ligase inhibitors that target cellular DNA replication and repairTwo DNA-binding and nick recognition modules in human DNA ligase IIIAn alternative splicing event which occurs in mouse pachytene spermatocytes generates a form of DNA ligase III with distinct biochemical properties that may function in meiotic recombinationMolecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombinationAlternative Okazaki Fragment Ligation Pathway by DNA Ligase IIIOverview of base excision repair biochemistryChronic Replication Problems Impact Cell Morphology and Adhesion of DNA Ligase I Defective CellsArabidopsis DNA ligase IV is induced by gamma-irradiation and interacts with an Arabidopsis homologue of the double strand break repair protein XRCC4.Unligated Okazaki Fragments Induce PCNA Ubiquitination and a Requirement for Rad59-Dependent Replication Fork Progression.Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinaseMechanism of nonhomologous end-joining in mycobacteria: a low-fidelity repair system driven by Ku, ligase D and ligase CGenome-wide ENU mutagenesis in combination with high density SNP analysis and exome sequencing provides rapid identification of novel mouse models of developmental diseaseAberrant DNA repair and DNA replication due to an inherited enzymatic defect in human DNA ligase IThe protein components and mechanism of eukaryotic Okazaki fragment maturation.Structure of the human DNA ligase I gene.CODA: accurate detection of functional associations between proteins in eukaryotic genomes using domain fusion.Coordinating DNA polymerase traffic during high and low fidelity synthesis.Hypomorphic PCNA mutation underlies a human DNA repair disorder.DNA ligase I is recruited to sites of DNA replication by an interaction with proliferating cell nuclear antigen: identification of a common targeting mechanism for the assembly of replication factoriesImmunodeficiency associated with DNA repair defects.An insight into the abundant proteome of 46BR.1G1 fibroblasts deficient of DNA ligase I.Combined transcriptome and genome analysis of single micrometastatic cells.Mammalian DNA single-strand break repair: an X-ra(y)ted affair.Structure and function of the DNA ligases encoded by the mammalian LIG3 gene.DNA ligases as therapeutic targetsImproving the fidelity of Thermus thermophilus DNA ligase.Two distinct DNA ligase activities in mitotic extracts of the yeast Saccharomyces cerevisiae.
P2860
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P2860
Mutations in the DNA ligase I gene of an individual with immunodeficiencies and cellular hypersensitivity to DNA-damaging agents.
description
1992 nî lūn-bûn
@nan
1992 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
name
Mutations in the DNA ligase I ...... tivity to DNA-damaging agents.
@ast
Mutations in the DNA ligase I ...... tivity to DNA-damaging agents.
@en
Mutations in the DNA ligase I ...... tivity to DNA-damaging agents.
@nl
type
label
Mutations in the DNA ligase I ...... tivity to DNA-damaging agents.
@ast
Mutations in the DNA ligase I ...... tivity to DNA-damaging agents.
@en
Mutations in the DNA ligase I ...... tivity to DNA-damaging agents.
@nl
prefLabel
Mutations in the DNA ligase I ...... tivity to DNA-damaging agents.
@ast
Mutations in the DNA ligase I ...... tivity to DNA-damaging agents.
@en
Mutations in the DNA ligase I ...... tivity to DNA-damaging agents.
@nl
P2093
P1433
P1476
Mutations in the DNA ligase I ...... tivity to DNA-damaging agents.
@en
P2093
A D Webster
A E Tomkinson
A R Lehmann
D E Barnes
P304
P356
10.1016/0092-8674(92)90450-Q
P407
P577
1992-05-01T00:00:00Z