An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III - Test2 - elhamkhani - TriplyDB

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

http://www.wikidata.org/entity/Q24615666

about

DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1 DNA ligase III and DNA ligase IV carry out genetically distinct forms of end joining in human somatic cells Mammalian DNA ligase III: molecular cloning, chromosomal localization, and expression in spermatocytes undergoing meiotic recombination Distinct kinetics of human DNA ligases I, IIIalpha, IIIbeta, and IV reveal direct DNA sensing ability and differential physiological functions in DNA repair Characterization of the XRCC1-DNA ligase III complex in vitro and its absence from mutant hamster cells The human XRCC9 gene corrects chromosomal instability and mutagen sensitivities in CHO UV40 cells Domain specific interaction in the XRCC1-DNA polymerase beta complex XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage The DNA ligase III zinc finger stimulates binding to DNA secondary structure and promotes end joining Mitochondrial DNA ligase III function is independent of Xrcc1.Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions A cell cycle-specific requirement for the XRCC1 BRCT II domain during mammalian DNA strand break repair Translocation of XRCC1 and DNA ligase IIIalpha from centrosomes to chromosomes in response to DNA damage in mitotic human cells Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein XRCC1 co-localizes and physically interacts with PCNA XRCC3 promotes homology-directed repair of DNA damage in mammalian cells DNA ligase III: a spotty presence in eukaryotes, but an essential function where tested DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair Eukaryotic DNA ligases: structural and functional insights Partial complementation of a DNA ligase I deficiency by DNA ligase III and its impact on cell survival and telomere stability in mammalian cells Antisense-mediated decrease in DNA ligase III expression results in reduced mitochondrial DNA integrity BRCT domains: easy as one, two, three Rational design of human DNA ligase inhibitors that target cellular DNA replication and repair An alternative splicing event which occurs in mouse pachytene spermatocytes generates a form of DNA ligase III with distinct biochemical properties that may function in meiotic recombination Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility Physical and functional interaction between DNA ligase IIIalpha and poly(ADP-Ribose) polymerase 1 in DNA single-strand break repair XRCC1 is required for DNA single-strand break repair in human cells.XRCC1 is phosphorylated by DNA-dependent protein kinase in response to DNA damage New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases Base excision repair and cancer DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]The structural basis for partitioning of the XRCC1/DNA ligase III- BRCT-mediated dimer complexes Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2 The Saccharomyces cerevisiae homologues of endonuclease III from Escherichia coli, Ntg1 and Ntg2, are both required for efficient repair of spontaneous and induced oxidative DNA damage in yeast

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P2860

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

http://www.wikidata.org/entity/Q24615666

description

1994 nî lūn-bûn

@nan

1994 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

1994 թվականի հունվարին հրատարակված գիտական հոդված

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1994年の論文

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1994年論文

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1994年論文

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1994年論文

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1994年論文

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1994年論文

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1994年论文

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name

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

@ast

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

@en

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

@nl

type

label

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

@ast

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

@en

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

@nl

prefLabel

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

@ast

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

@en

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

@nl

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Molecular and Cellular Biology

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An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

@en

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C K McKeown

http://www.w3.org/2001/XMLSchema#string

J D Tucker

http://www.w3.org/2001/XMLSchema#string

K W Caldecott

http://www.w3.org/2001/XMLSchema#string

L H Thompson

http://www.w3.org/2001/XMLSchema#string

S Ljungquist

http://www.w3.org/2001/XMLSchema#string

P2860

Instability and decay of the primary structure of DNA

Elevated sister chromatid exchange phenotype of Bloom syndrome cells is complemented by human chromosome 15

Molecular cloning of the human XRCC1 gene, which corrects defective DNA strand break repair and sister chromatid exchange

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

Use of T7 RNA polymerase to direct expression of cloned genes

The structure of an antigenic determinant in a protein

Structural alterations of DNA ligase I in Bloom syndrome

Mutations in the DNA ligase I gene of an individual with immunodeficiencies and cellular hypersensitivity to DNA-damaging agents.

Different mutations are responsible for the elevated sister-chromatid exchange frequencies characteristic of Bloom's syndrome and hamster EM9 cells.

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68-76

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scholarly article

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3668642

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10.1128/MCB.14.1.68

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1

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14

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1994-01-01T00:00:00Z

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8264637

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358357

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