Glycine 184 in nonstructural protein NS1 determines the virulence of influenza A virus strain PR8 without affecting the host interferon response.
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A Transient Homotypic Interaction Model for the Influenza A Virus NS1 Protein Effector DomainInfluenza virus activation of the interferon systemInfluenza A virus attenuation by codon deoptimization of the NS gene for vaccine developmentMolecular determinants of influenza virus pathogenesis in mice.Genetic evolution of low pathogenecity H9N2 avian influenza viruses in Tunisia: acquisition of new mutations.An influenza reassortant with polymerase of pH1N1 and NS gene of H3N2 influenza A virus is attenuated in vivo.Isolation and mutation trend analysis of influenza A virus subtype H9N2 in Egypt.Multifunctional adaptive NS1 mutations are selected upon human influenza virus evolution in the mouse.Nuclear localized Influenza nucleoprotein N-terminal deletion mutant is deficient in functional vRNP formation.The NS1 protein of influenza A virus interacts with cellular processing bodies and stress granules through RNA-associated protein 55 (RAP55) during virus infectionInfluenza A virus NS1 gene mutations F103L and M106I increase replication and virulence.Replication-competent influenza A viruses expressing a red fluorescent protein.The virulence of 1997 H5N1 influenza viruses in the mouse model is increased by correcting a defect in their NS1 proteins.Influenza virus pathophysiology and brain invasion in mice with functional and dysfunctional Mx1 genes.Fluorescence-Activated Cell Sorting-Based Analysis Reveals an Asymmetric Induction of Interferon-Stimulated Genes in Response to Seasonal Influenza A VirusDownregulating viral gene expression: codon usage bias manipulation for the generation of novel influenza A virus vaccines.Role of N Terminus-Truncated NS1 Proteins of Influenza A Virus in Inhibiting IRF3 Activation.Arenavirus reverse genetics for vaccine developmentInfluenza A/Hong Kong/156/1997(H5N1) virus NS1 gene mutations F103L and M106I both increase IFN antagonism, virulence and cytoplasmic localization but differ in binding to RIG-I and CPSF30Evolution of an avian H5N1 influenza A virus escape mutantLung cytokine gene expression is correlated with increased severity of disease in a novel H4N8 influenza virus isolated from shorebirds.Single-cell studies of IFN-β promoter activation by wild-type and NS1-defective influenza A viruses.G45R on nonstructural protein 1 of influenza A virus contributes to virulence by increasing the expression of proinflammatory cytokines in mice.Influenza A virus NS1 protein-induced JNK activation and apoptosis are not functionally linked.Recombinant influenza A viruses with enhanced levels of PB1 and PA viral protein expression.Emergence of a C-terminal seven-amino-acid elongation of NS1 in around 1950 conferred a minor growth advantage to former seasonal influenza A viruses.A single amino acid substitution in the novel H7N9 influenza A virus NS1 protein increases CPSF30 binding and virulence.Methionine-101 from one strain of H5N1 NS1 protein determines its IFN-antagonizing ability and subcellular distribution pattern.Treating Influenza Infection, From Now and Into the FutureIdentification of Amino Acid Residues Responsible for Inhibition of Host Gene Expression by Influenza A H9N2 NS1 Targeting of CPSF30Host Shutoff in Influenza A Virus: Many Means to an End
P2860
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P2860
Glycine 184 in nonstructural protein NS1 determines the virulence of influenza A virus strain PR8 without affecting the host interferon response.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Glycine 184 in nonstructural p ...... the host interferon response.
@ast
Glycine 184 in nonstructural p ...... the host interferon response.
@en
Glycine 184 in nonstructural p ...... the host interferon response.
@nl
type
label
Glycine 184 in nonstructural p ...... the host interferon response.
@ast
Glycine 184 in nonstructural p ...... the host interferon response.
@en
Glycine 184 in nonstructural p ...... the host interferon response.
@nl
prefLabel
Glycine 184 in nonstructural p ...... the host interferon response.
@ast
Glycine 184 in nonstructural p ...... the host interferon response.
@en
Glycine 184 in nonstructural p ...... the host interferon response.
@nl
P2093
P2860
P50
P356
P1433
P1476
Glycine 184 in nonstructural p ...... the host interferon response.
@en
P2093
Georg Kochs
Markus Mordstein
Peter Stäheli
Sabine Steidle
P2860
P304
12761-12770
P356
10.1128/JVI.00701-10
P407
P577
2010-10-06T00:00:00Z