Host and viral determinants for MxB restriction of HIV-1 infection. - Test2 - elhamkhani - TriplyDB

Host and viral determinants for MxB restriction of HIV-1 infection.

Host and viral determinants for MxB restriction of HIV-1 infection.

http://www.wikidata.org/entity/Q34422979

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Misdelivery at the Nuclear Pore Complex-Stopping a Virus Dead in Its Tracks Evolutionary Analyses Suggest a Function of MxB Immunity Proteins Beyond Lentivirus Restriction Key determinants of target DNA recognition by retroviral intasomes.A triple-arginine motif in the amino-terminal domain and oligomerization are required for HIV-1 inhibition by human MX2 Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal Structural basis for retroviral integration into nucleosomes.Integrated and Total HIV-1 DNA Predict Ex Vivo Viral Outgrowth Amplification, Next-generation Sequencing, and Genomic DNA Mapping of Retroviral Integration Sites.Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration.Oligomerization Requirements for MX2-Mediated Suppression of HIV-1 Infection A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin.SUN2 Overexpression Deforms Nuclear Shape and Inhibits HIV.The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency.The Cleavage and Polyadenylation Specificity Factor 6 (CPSF6) Subunit of the Capsid-recruited Pre-messenger RNA Cleavage Factor I (CFIm) Complex Mediates HIV-1 Integration into Genes.Accumulation of MxB/Mx2-resistant HIV-1 Capsid Variants During Expansion of the HIV-1 Epidemic in Human Populations Mechanisms of HIV-1 Control.Cyclophilin A potentiates TRIM5α inhibition of HIV-1 nuclear import without promoting TRIM5α binding to the viral capsid.MxB Is Not Responsible for the Blocking of HIV-1 Infection Observed in Alpha Interferon-Treated Cells.Mx oligomer: a novel capsid pattern sensor?Capsid-Dependent Host Factors in HIV-1 Infection.Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4+ T Cells In Vitro.Capsid-CPSF6 Interaction Is Dispensable for HIV-1 Replication in Primary Cells but Is Selected during Virus Passage In Vivo.Roles of Capsid-Interacting Host Factors in Multimodal Inhibition of HIV-1 by PF74.The highly polymorphic cyclophilin A-binding loop in HIV-1 capsid modulates viral resistance to MxB.CryoEM structure of MxB reveals a novel oligomerization interface critical for HIV restriction.Hijacking of the Ubiquitin/Proteasome Pathway by the HIV Auxiliary Proteins.Are Evolution and the Intracellular Innate Immune System Key Determinants in HIV Transmission?Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2 Equine Myxovirus Resistance Protein 2 Restricts Lentiviral Replication by Blocking Nuclear Uptake of Capsid Protein

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Host and viral determinants for MxB restriction of HIV-1 infection.

http://www.wikidata.org/entity/Q34422979

description

2014 nî lūn-bûn

@nan

2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

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2014年論文

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2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Host and viral determinants for MxB restriction of HIV-1 infection.

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Host and viral determinants for MxB restriction of HIV-1 infection.

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Host and viral determinants for MxB restriction of HIV-1 infection.

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type

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Host and viral determinants for MxB restriction of HIV-1 infection.

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Host and viral determinants for MxB restriction of HIV-1 infection.

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Host and viral determinants for MxB restriction of HIV-1 infection.

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Host and viral determinants for MxB restriction of HIV-1 infection.

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Host and viral determinants for MxB restriction of HIV-1 infection.

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Host and viral determinants for MxB restriction of HIV-1 infection.

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Host and viral determinants for MxB restriction of HIV-1 infection.

@en

P2093

Alan Engelman

http://www.w3.org/2001/XMLSchema#string

Erik Serrao

http://www.w3.org/2001/XMLSchema#string

Henry L Levin

http://www.w3.org/2001/XMLSchema#string

Parmit Kumar Singh

http://www.w3.org/2001/XMLSchema#string

Weifeng Wang

http://www.w3.org/2001/XMLSchema#string

P2860

Inhibition of nuclear import and cell-cycle progression by mutated forms of the dynamin-like GTPase MxB

HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency

Human MxB protein, an interferon-alpha-inducible GTPase, contains a nuclear targeting signal and is localized in the heterochromatin region beneath the nuclear envelope

Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection

MX2 is an interferon-induced inhibitor of HIV-1 infection

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

A diverse range of gene products are effectors of the type I interferon antiviral response

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

The human genome browser at UCSC

BLAT--the BLAST-like alignment tool

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10.1186/S12977-014-0090-Z

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11

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Kenneth A Matreyek

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