Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence. - Test2 - elhamkhani - TriplyDB

Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence.

Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence.

http://www.wikidata.org/entity/Q34443272

about

Lessons learned from next-generation sequencing in head and neck cancer Another fork in the road--life or death decisions by the tumour suppressor p53 Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence code The coordinated p53 and estrogen receptor cis-regulation at an FLT1 promoter SNP is specific to genotoxic stress and estrogenic compound Effects of ploidy and recombination on evolution of robustness in a model of the segment polarity network p53 transactivation and the impact of mutations, cofactors and small molecules using a simplified yeast-based screening system Quantitative Analysis of NF-κB Transactivation Specificity Using a Yeast-Based Functional Assay Early onset sebaceous carcinoma.Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity Estrogen receptor acting in cis enhances WT and mutant p53 transactivation at canonical and noncanonical p53 target sequences.Modeling cancer progression via pathway dependencies Noncanonical DNA motifs as transactivation targets by wild type and mutant p53 Parallel analysis of tetramerization domain mutants of the human p53 protein using PCR colonies.Regression based predictor for p53 transactivation.Stress-specific response of the p53-Mdm2 feedback loop TP53 mutations in human cancers: origins, consequences, and clinical use ∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites.Homoeolog-specific transcriptional bias in allopolyploid wheat Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation.Altered-function p53 missense mutations identified in breast cancers can have subtle effects on transactivation.Human single-nucleotide polymorphisms alter p53 sequence-specific binding at gene regulatory elements.Compensatory cis-trans evolution and the dysregulation of gene expression in interspecific hybrids of Drosophila P53 family members modulate the expression of PRODH, but not PRODH2, via intronic p53 response elements.Formation of stress-specific p53 binding patterns is influenced by chromatin but not by modulation of p53 binding affinity to response elements Fine-tuning p53 activity through C-terminal modification significantly contributes to HSC homeostasis and mouse radiosensitivity The Ribosomal Protein-Mdm2-p53 Pathway and Energy Metabolism: Bridging the Gap between Feast and Famine.The complex interactions of p53 with target DNA: we learn as we go.Dose-dependent dual role of PIT-1 (POU1F1) in somatolactotroph cell proliferation and apoptosis Evolution of p53 transactivation specificity through the lens of a yeast-based functional assay p53 and p73 display common and distinct requirements for sequence specific binding to DNA Whole-genome cartography of p53 response elements ranked on transactivation potential.Sequence analysis of p53 response-elements suggests multiple binding modes of the p53 tetramer to DNA targets A single-nucleotide polymorphism in a half-binding site creates p53 and estrogen receptor control of vascular endothelial growth factor receptor 1.Functional analyses of human DNA repair proteins important for aging and genomic stability using yeast genetics The tumor suppressor gene TP53: implications for cancer management and therapy.DGCA: A comprehensive R package for Differential Gene Correlation Analysis.Low-level p53 expression changes transactivation rules and reveals superactivating sequences.Transcriptional functionality of germ line p53 mutants influences cancer phenotype.Functional evolution of the p53 regulatory network through its target response elements.Changing the p53 master regulatory network: ELEMENTary, my dear Mr Watson.

P2860

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P2860

Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence.

http://www.wikidata.org/entity/Q34443272

description

2002 nî lūn-bûn

@nan

2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2002年の論文

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2002年論文

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2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

name

Differential transactivation b ...... and promoter target sequence.

@ast

Differential transactivation b ...... and promoter target sequence.

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Differential transactivation b ...... and promoter target sequence.

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type

label

Differential transactivation b ...... and promoter target sequence.

@ast

Differential transactivation b ...... and promoter target sequence.

@en

Differential transactivation b ...... and promoter target sequence.

@nl

prefLabel

Differential transactivation b ...... and promoter target sequence.

@ast

Differential transactivation b ...... and promoter target sequence.

@en

Differential transactivation b ...... and promoter target sequence.

@nl

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MCB.22.24.8612-8625.2002

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Molecular and Cellular Biology

P1476

Differential transactivation b ...... l and promoter target sequence

@en

P2093

Alberto Inga

http://www.w3.org/2001/XMLSchema#string

Francesca Storici

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Thomas A Darden

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P2860

Increased apoptosis induction by 121F mutant p53

PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

Regulation of p53 activity in nuclear bodies by a specific PML isoform

PUMA induces the rapid apoptosis of colorectal cancer cells

Negative control of p53 by Sir2alpha promotes cell survival under stress

ASPP proteins specifically stimulate the apoptotic function of p53

Mdm2 promotes the rapid degradation of p53

The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression.

hADA3 is required for p53 activity

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8612-8625

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scholarly article

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10.1128/MCB.22.24.8612-8625.2002

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24

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22

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Michael A Resnick

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2002-12-01T00:00:00Z

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12446780

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