PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes
about
The transcription factor p53: not a repressor, solely an activatorSestrins at the crossroad between stress and agingThe peroxiredoxin repair proteinsGene expression profiling revealed novel mechanism of action of Taxotere and Furtulon in prostate cancer cellsRole of the p53 tumor suppressor in metabolismThe role of tumor suppressor p53 in the antioxidant defense and metabolismPostnatal glucocorticoid-induced hypomyelination, gliosis, and neurologic deficits are dose-dependent, preparation-specific, and reversiblep53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signalingFOXO forkhead transcription factors induce G(2)-M checkpoint in response to oxidative stressSestrin as a feedback inhibitor of TOR that prevents age-related pathologiesDifferent oxidative stress response in keratinocytes and fibroblasts of reconstructed skin exposed to non extreme daily-ultraviolet radiationThe antioxidant function of the p53 tumor suppressorEndothelin receptor B antagonists decrease glioma cell viability independently of their cognate receptor.t(6;9)(p22;q34)/DEK-NUP214-rearranged pediatric myeloid leukemia: an international study of 62 patients.Sestrin 1 ameliorates cardiac hypertrophy via autophagy activation.Sestrin2 modulates AMPK subunit expression and its response to ionizing radiation in breast cancer cells.Sestrins orchestrate cellular metabolism to attenuate aging.Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence.Lack of p53 affects the expression of several brain mitochondrial proteins: insights from proteomics into important pathways regulated by p53."Super p53" mice display retinal astroglial changes.Sestrin2 protein positively regulates AKT enzyme signaling and survival in human squamous cell carcinoma and melanoma cells.Ranked prediction of p53 targets using hidden variable dynamic modeling.The many forks in FOXO's road.The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor.Quercetin and cancer chemopreventionSestrin 2 protein regulates platelet-derived growth factor receptor β (Pdgfrβ) expression by modulating proteasomal and Nrf2 transcription factor functions.An ShRNA Based Genetic Screen Identified Sesn2 as a Potential Tumor Suppressor in Lung Cancer via Suppression of Akt-mTOR-p70S6K SignalingPoly(ADP-ribose) polymerase inhibition enhances p53-dependent and -independent DNA damage responses induced by DNA damaging agent.ATM regulates cell fate choice upon p53 activation by modulating mitochondrial turnover and ROS levels.Metabolic regulation of oxygen and redox homeostasis by p53: lessons from evolutionary biology?Roles of Sestrin2 and Ribosomal Protein S6 in Transient Global Ischemia-Induced Hippocampal Neuronal InjuryGenomic alterations associated with loss of heterozygosity for TP53 in Li-Fraumeni syndrome fibroblasts.Tumor suppressive role of sestrin2 during colitis and colon carcinogenesis.Sestrin regulation of TORC1: Is Sestrin a leucine sensor?Versatile functions of p53 protein in multicellular organismsHomeostatic functions of the p53 tumor suppressor: regulation of energy metabolism and antioxidant defense.The dark side of a tumor suppressor: anti-apoptotic p53.p53 strikes mTORC1 by employing sestrins.Sestrin 3 regulation in type 2 diabetic patients and its influence on metabolism and differentiation in skeletal muscle.A sestrin-dependent Erk-Jnk-p38 MAPK activation complex inhibits immunity during aging
P2860
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P2860
PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
PA26, a novel target of the p5 ...... growth arrest inducible genes
@ast
PA26, a novel target of the p5 ...... growth arrest inducible genes
@en
PA26, a novel target of the p5 ...... growth arrest inducible genes
@en-gb
PA26, a novel target of the p5 ...... growth arrest inducible genes
@nl
type
label
PA26, a novel target of the p5 ...... growth arrest inducible genes
@ast
PA26, a novel target of the p5 ...... growth arrest inducible genes
@en
PA26, a novel target of the p5 ...... growth arrest inducible genes
@en-gb
PA26, a novel target of the p5 ...... growth arrest inducible genes
@nl
prefLabel
PA26, a novel target of the p5 ...... growth arrest inducible genes
@ast
PA26, a novel target of the p5 ...... growth arrest inducible genes
@en
PA26, a novel target of the p5 ...... growth arrest inducible genes
@en-gb
PA26, a novel target of the p5 ...... growth arrest inducible genes
@nl
P2093
P356
P1433
P1476
PA26, a novel target of the p5 ...... growth arrest inducible genes
@en
P2093
B Seizinger
L Buckbinder
S Velasco-Miguel
P2888
P304
P356
10.1038/SJ.ONC.1202274
P407
P577
1999-01-07T00:00:00Z
P5875
P6179
1036577903