Tryptophan 7-halogenase (PrnA) structure suggests a mechanism for regioselective chlorination.
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BluB cannibalizes flavin to form the lower ligand of vitamin B12What's new in enzymatic halogenationsInsights into enzymatic halogenation from computational studiesFlavoenzymes: versatile catalysts in biosynthetic pathwaysStructure of the monooxygenase component of a two-component flavoprotein monooxygenaseCrystal structure of the oxygenase component (HpaB) of the 4-hydroxyphenylacetate 3-monooxygenase from Thermus thermophilus HB8The Second Enzyme in Pyrrolnitrin Biosynthetic Pathway Is Related to the Heme-Dependent Dioxygenase Superfamily †Mechanism of Enzymatic Fluorination in Streptomyces c attleyaNew Insights into the Mechanism of Enzymatic Chlorination of TryptophanThe FAD Cofactor of RebC Shifts to an IN Conformation upon Flavin Reduction † , ‡Structural Insights into Regioselectivity in the Enzymatic Chlorination of TryptophanHalomethane Biosynthesis: Structure of a SAM-Dependent Halide Methyltransferase from Arabidopsis thalianaThe ternary complex of PrnB (the second enzyme in the pyrrolnitrin biosynthesis pathway), tryptophan, and cyanide yields new mechanistic insights into the indolamine dioxygenase superfamilyA Structure-Guided Switch in the Regioselectivity of a Tryptophan HalogenaseStructure and biocatalytic scope of thermophilic flavin-dependent halogenase and flavin reductase enzymesDynamics and mechanisms of DNA repair by photolyaseThe purification, crystallization and preliminary structural characterization of FAD-dependent monooxygenase PhzS, a phenazine-modifying enzyme from Pseudomonas aeruginosaBiosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pairSpecific sequence motifs direct the oxygenation and chlorination of tryptophan by myeloperoxidase.Microbisporicin gene cluster reveals unusual features of lantibiotic biosynthesis in actinomycetes.A flavin-dependent halogenase catalyzes the chlorination step in the biosynthesis of Dictyostelium differentiation-inducing factor 1.Arenium ions are not obligatory intermediates in electrophilic aromatic substitution.Insights into radicicol biosynthesis via heterologous synthesis of intermediates and analogsChanging the regioselectivity of the tryptophan 7-halogenase PrnA by site-directed mutagenesis.Regioselective arene halogenation using the FAD-dependent halogenase RebH.Enzymatic halogenation of tryptophan on a gram scale.Directed evolution of RebH for site-selective halogenation of large biologically active molecules.The fluorinase from Streptomyces cattleya is also a chlorinaseUnusual flavoenzyme catalysis in marine bacteria.Directed Evolution of RebH for Catalyst-Controlled Halogenation of Indole C-H BondsDivergent pathways in the biosynthesis of bisindole natural products.Independent Evolution of Six Families of Halogenating Enzymes.A High-Throughput Fluorescence Assay to Determine the Activity of Tryptophan Halogenases.Anion-π Interactions in Flavoproteins Involve a Substantial Charge-Transfer Component.Form follows function: structural and catalytic variation in the class a flavoprotein monooxygenases.Specific chlorination of isoquinolines by a fungal flavin-dependent halogenase.Explorations of catalytic domains in non-ribosomal peptide synthetase enzymologyHalogenase genes in nonribosomal peptide synthetase gene clusters of Microcystis (cyanobacteria): sporadic distribution and evolution.Chlorination diversifies Cimicifuga racemosa triterpene glycosides.Regiospecific chlorination of (S)-beta-tyrosyl-S-carrier protein catalyzed by SgcC3 in the biosynthesis of the enediyne antitumor antibiotic C-1027
P2860
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P2860
Tryptophan 7-halogenase (PrnA) structure suggests a mechanism for regioselective chlorination.
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Tryptophan 7-halogenase (PrnA) ...... r regioselective chlorination.
@ast
Tryptophan 7-halogenase (PrnA) ...... r regioselective chlorination.
@en
Tryptophan 7-halogenase
@nl
type
label
Tryptophan 7-halogenase (PrnA) ...... r regioselective chlorination.
@ast
Tryptophan 7-halogenase (PrnA) ...... r regioselective chlorination.
@en
Tryptophan 7-halogenase
@nl
prefLabel
Tryptophan 7-halogenase (PrnA) ...... r regioselective chlorination.
@ast
Tryptophan 7-halogenase (PrnA) ...... r regioselective chlorination.
@en
Tryptophan 7-halogenase
@nl
P2093
P2860
P356
P1433
P1476
Tryptophan 7-halogenase (PrnA) ...... r regioselective chlorination.
@en
P2093
Changjiang Dong
Karl-Heinz van Pée
Silvana Flecks
Susanne Unversucht
P2860
P304
P356
10.1126/SCIENCE.1116510
P407
P577
2005-09-01T00:00:00Z