CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice. - Test2 - elhamkhani - TriplyDB

CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice.

CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice.

http://www.wikidata.org/entity/Q34499647

about

Genome editing: the road of CRISPR/Cas9 from bench to clinic Using CRISPR/Cas to study gene function and model disease in vivo Genetically engineered mouse models in oncology research and cancer medicine Identification of biomarkers of intrahepatic cholangiocarcinoma via integrated analysis of mRNA and miRNA microarray data CRISPR/Cas9: Transcending the Reality of Genome Editing.Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma.Applications of CRISPR technologies in research and beyond.piggyBac mediates efficient in vivo CRISPR library screening for tumorigenesis in mice Tissue-specific tumorigenesis: context matters.Modeling invasive lobular breast carcinoma by CRISPR/Cas9-mediated somatic genome editing of the mammary gland.Progress and Application of CRISPR/Cas Technology in Biological and Biomedical Investigation.Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice.The application of somatic CRISPR-Cas9 to conditional genome editing in Caenorhabditis elegans.Addressing intra-tumoral heterogeneity and therapy resistance.The present and future of genome editing in cancer research.Applications of the CRISPR/Cas9 system in murine cancer modeling.CRISPR/Cas9: at the cutting edge of hepatology.Mouse models of metastasis: progress and prospects.Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.Intrinsic and environmental factors in intrahepatic cholangiocarcinoma development.An in vivo transfection system for inducible gene expression and gene silencing in murine hepatocytes.Rapid Construction of Multiplexed CRISPR-Cas9 Systems for Plant Genome Editing.Combinatorial genetics in liver repopulation and carcinogenesis with a novel in vivo CRISPR activation platform.Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity.CRISPR-Cas9: a promising genetic engineering approach in cancer research.Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes.Constitutive and Inducible Systems for Genetic In Vivo Modification of Mouse Hepatocytes Using Hydrodynamic Tail Vein Injection.Preclinical mouse solid tumour models: status quo, challenges and perspectives.Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling.In vivo genome editing thrives with diversified CRISPR technologies.Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening.The past and presence of gene targeting: from chemicals and DNA via proteins to RNA.Pancreas 3D Organoids: Current and Future Aspects as a Research Platform for Personalized Medicine in Pancreatic Cancer.In Vivo Applications of CRISPR-Based Genome Editing in the Retina.Emergence of Intrahepatic Cholangiocarcinoma: How High-Throughput Technologies Expedite the Solutions for a Rare Cancer Type Hepatocellular carcinoma Mouse models in the era of large human tumour sequencing studies

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CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice.

http://www.wikidata.org/entity/Q34499647

description

2015 nî lūn-bûn

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2015 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2015 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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CRISPR/Cas9 somatic multiplex- ...... ional cancer genomics in mice.

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CRISPR/Cas9 somatic multiplex- ...... ional cancer genomics in mice.

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CRISPR/Cas9 somatic multiplex- ...... ional cancer genomics in mice.

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CRISPR/Cas9 somatic multiplex- ...... ional cancer genomics in mice.

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CRISPR/Cas9 somatic multiplex- ...... ional cancer genomics in mice.

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CRISPR/Cas9 somatic multiplex- ...... ional cancer genomics in mice.

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CRISPR/Cas9 somatic multiplex- ...... ional cancer genomics in mice.

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CRISPR/Cas9 somatic multiplex- ...... ional cancer genomics in mice.

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Proceedings of the National Academy of Sciences of the United States of America

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CRISPR/Cas9 somatic multiplex- ...... ional cancer genomics in mice.

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Alexander Strong

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Beiyuan Fu

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Detian Yuan

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Dieter Saur

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Fengtang Yang

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Günter Schneider

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Irene Esposito

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Irina Heid

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Julia Weber

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Mathias Friedrich

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P2860

RNA-guided human genome engineering via Cas9

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

Multiplex genome engineering using CRISPR/Cas systems

Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators

The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA

One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

RNA-guided genetic silencing systems in bacteria and archaea

CRISPR/Cas, the immune system of bacteria and archaea

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13982-13987

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45

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112

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George S Vassiliou

Sebastian Lange

Jorge de la Rosa

Juan Cadiñanos

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2015-10-27T00:00:00Z

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26508638

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