CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice.
about
Genome editing: the road of CRISPR/Cas9 from bench to clinicUsing CRISPR/Cas to study gene function and model disease in vivoGenetically engineered mouse models in oncology research and cancer medicineIdentification of biomarkers of intrahepatic cholangiocarcinoma via integrated analysis of mRNA and miRNA microarray dataCRISPR/Cas9: Transcending the Reality of Genome Editing.Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma.Applications of CRISPR technologies in research and beyond.piggyBac mediates efficient in vivo CRISPR library screening for tumorigenesis in miceTissue-specific tumorigenesis: context matters.Modeling invasive lobular breast carcinoma by CRISPR/Cas9-mediated somatic genome editing of the mammary gland.Progress and Application of CRISPR/Cas Technology in Biological and Biomedical Investigation.Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice.The application of somatic CRISPR-Cas9 to conditional genome editing in Caenorhabditis elegans.Addressing intra-tumoral heterogeneity and therapy resistance.The present and future of genome editing in cancer research.Applications of the CRISPR/Cas9 system in murine cancer modeling.CRISPR/Cas9: at the cutting edge of hepatology.Mouse models of metastasis: progress and prospects.Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.Intrinsic and environmental factors in intrahepatic cholangiocarcinoma development.An in vivo transfection system for inducible gene expression and gene silencing in murine hepatocytes.Rapid Construction of Multiplexed CRISPR-Cas9 Systems for Plant Genome Editing.Combinatorial genetics in liver repopulation and carcinogenesis with a novel in vivo CRISPR activation platform.Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity.CRISPR-Cas9: a promising genetic engineering approach in cancer research.Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes.Constitutive and Inducible Systems for Genetic In Vivo Modification of Mouse Hepatocytes Using Hydrodynamic Tail Vein Injection.Preclinical mouse solid tumour models: status quo, challenges and perspectives.Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling.In vivo genome editing thrives with diversified CRISPR technologies.Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening.The past and presence of gene targeting: from chemicals and DNA via proteins to RNA.Pancreas 3D Organoids: Current and Future Aspects as a Research Platform for Personalized Medicine in Pancreatic Cancer.In Vivo Applications of CRISPR-Based Genome Editing in the Retina.Emergence of Intrahepatic Cholangiocarcinoma: How High-Throughput Technologies Expedite the Solutions for a Rare Cancer TypeHepatocellular carcinomaMouse models in the era of large human tumour sequencing studies
P2860
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P2860
CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice.
description
2015 nî lūn-bûn
@nan
2015 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
CRISPR/Cas9 somatic multiplex- ...... ional cancer genomics in mice.
@ast
CRISPR/Cas9 somatic multiplex- ...... ional cancer genomics in mice.
@en
CRISPR/Cas9 somatic multiplex- ...... ional cancer genomics in mice.
@nl
type
label
CRISPR/Cas9 somatic multiplex- ...... ional cancer genomics in mice.
@ast
CRISPR/Cas9 somatic multiplex- ...... ional cancer genomics in mice.
@en
CRISPR/Cas9 somatic multiplex- ...... ional cancer genomics in mice.
@nl
prefLabel
CRISPR/Cas9 somatic multiplex- ...... ional cancer genomics in mice.
@ast
CRISPR/Cas9 somatic multiplex- ...... ional cancer genomics in mice.
@en
CRISPR/Cas9 somatic multiplex- ...... ional cancer genomics in mice.
@nl
P2093
P2860
P50
P356
P1476
CRISPR/Cas9 somatic multiplex- ...... ional cancer genomics in mice.
@en
P2093
Alexander Strong
Beiyuan Fu
Detian Yuan
Dieter Saur
Fengtang Yang
Günter Schneider
Irene Esposito
Irina Heid
Julia Weber
Mathias Friedrich
P2860
P304
13982-13987
P356
10.1073/PNAS.1512392112
P407
P50
P577
2015-10-27T00:00:00Z