A C-terminal lysine that controls human P2X4 receptor desensitization.
about
Primitive ATP-activated P2X receptors: discovery, function and pharmacologyMolecular and functional properties of P2X receptors--recent progress and persisting challengesExploring the ATP-binding site of P2X receptorsBrain-derived neurotrophic factor from microglia: a molecular substrate for neuropathic painEndocytosis and Trafficking of Natriuretic Peptide Receptor-A: Potential Role of Short Sequence MotifsFusion-activated Ca2+ entry via vesicular P2X4 receptors promotes fusion pore opening and exocytotic content release in pneumocytesP2X4 receptors in activated C8-B4 cells of cerebellar microglial origin.The carbon monoxide donor, CORM-2, is an antagonist of ATP-gated, human P2X4 receptors.Small peptide recognition sequence for intracellular sorting.Structural insights into the function of P2X4: an ATP-gated cation channel of neuroendocrine cells.The penultimate arginine of the carboxyl terminus determines slow desensitization in a P2X receptor from the cattle tick Boophilus microplusPrincipal component analysis of binding energies for single-point mutants of hT2R16 bound to an agonist correlate with experimental mutant cell responseActivation and regulation of purinergic P2X receptor channelsCysteine substitution mutagenesis and the effects of methanethiosulfonate reagents at P2X2 and P2X4 receptors support a core common mode of ATP action at P2X receptors.Phosphoinositides regulate P2X4 ATP-gated channels through direct interactions.Subtype-specific regulation of P2X3 and P2X2/3 receptors by phosphoinositides in peripheral nociceptors.Amyloid-beta induces a caspase-mediated cleavage of P2X4 to promote purinotoxicity.Functional evidence for the expression of P2X1, P2X4 and P2X7 receptors in human lung mast cells.Functional roles of short sequence motifs in the endocytosis of membrane receptors.ATP receptors gate microglia signaling in neuropathic pain.P2X4 purinoceptor signaling in chronic pain.Calcium-permeable ion channels in pain signaling.Key sites for P2X receptor function and multimerization: overview of mutagenesis studies on a structural basis.P2X Receptor Activation.Highly conserved tyrosine 37 stabilizes desensitized states and restricts calcium permeability of ATP-gated P2X3 receptor.Amitriptyline does not block the action of ATP at human P2X4 receptor.Atypical P2X receptor pharmacology in two human osteoblast-like cell lines.Molecular shape, architecture, and size of P2X4 receptors determined using fluorescence resonance energy transfer and electron microscopyThe intracellular amino terminus plays a dominant role in desensitization of ATP-gated P2X receptor ion channels.Contribution of the region Glu181 to Val200 of the extracellular loop of the human P2X1 receptor to agonist binding and gating revealed using cysteine scanning mutagenesis.Contribution of the intracellular C terminal domain to regulation of human P2X1 receptors for ATP by phorbol ester and Gq coupled mGlu(1α) receptors.Fluvastatin suppresses native and recombinant human P2X4 receptor function.Amino acid residues constituting the agonist binding site of the human P2X3 receptorRoles of ectodomain and transmembrane regions in ethanol and agonist action in purinergic P2X2 and P2X3 receptors.Rab5 regulates internalisation of P2X4 receptors and potentiation by ivermectin.Involvement of P2X4 receptors in hippocampal microglial activation after status epilepticus.A positive inotropic effect of ATP in the human cardiac atrium.P2X4 Receptor-Dependent Ca2+ Influx in Model Human Monocytes and Macrophages.ATP Evokes Ca2+ Responses and CXCL5 Secretion via P2X4 Receptor Activation in Human Monocyte-Derived Macrophages.Pyridoxal-5'-phosphate (MC-1), a vitamin B6 derivative, inhibits expressed P2X receptors.
P2860
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P2860
A C-terminal lysine that controls human P2X4 receptor desensitization.
description
2006 nî lūn-bûn
@nan
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
A C-terminal lysine that controls human P2X4 receptor desensitization.
@ast
A C-terminal lysine that controls human P2X4 receptor desensitization.
@en
A C-terminal lysine that controls human P2X4 receptor desensitization.
@nl
type
label
A C-terminal lysine that controls human P2X4 receptor desensitization.
@ast
A C-terminal lysine that controls human P2X4 receptor desensitization.
@en
A C-terminal lysine that controls human P2X4 receptor desensitization.
@nl
prefLabel
A C-terminal lysine that controls human P2X4 receptor desensitization.
@ast
A C-terminal lysine that controls human P2X4 receptor desensitization.
@en
A C-terminal lysine that controls human P2X4 receptor desensitization.
@nl
P2860
P356
P1476
A C-terminal lysine that controls human P2X4 receptor desensitization.
@en
P2093
R Alan North
Samuel J Fountain
P2860
P304
15044-15049
P356
10.1074/JBC.M600442200
P407
P577
2006-03-13T00:00:00Z