Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation. - Test2 - elhamkhani - TriplyDB

Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation.

Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation.

http://www.wikidata.org/entity/Q34521887

about

CARMA2sh and ULK2 control pathogen-associated molecular patterns recognition in human keratinocytes: psoriasis-linked CARMA2sh mutants escape ULK2 censorship.The E3 Ubiquitin Ligase RNF7 Negatively Regulates CARD14/CARMA2sh Signaling.Essential Role of CARD14 in Murine Experimental Psoriasis.Ancient Origin of the CARD-Coiled Coil/Bcl10/MALT1-Like Paracaspase Signaling Complex Indicates Unknown Critical Functions.CARD14/CARMA2 Signaling and its Role in Inflammatory Skin Disorders Clinical and Genetic Heterogeneity of Mutations in Psoriatic Skin Disease Epithelial TRAF6 drives IL-17-mediated psoriatic inflammation

P2860

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P2860

Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation.

http://www.wikidata.org/entity/Q34521887

description

2016 nî lūn-bûn

@nan

2016 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2016 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

name

Psoriasis mutations disrupt CA ...... T1-dependent NF-κB activation.

@ast

Psoriasis mutations disrupt CA ...... T1-dependent NF-κB activation.

@en

Psoriasis mutations disrupt CA ...... T1-dependent NF-κB activation.

@nl

type

label

Psoriasis mutations disrupt CA ...... T1-dependent NF-κB activation.

@ast

Psoriasis mutations disrupt CA ...... T1-dependent NF-κB activation.

@en

Psoriasis mutations disrupt CA ...... T1-dependent NF-κB activation.

@nl

prefLabel

Psoriasis mutations disrupt CA ...... T1-dependent NF-κB activation.

@ast

Psoriasis mutations disrupt CA ...... T1-dependent NF-κB activation.

@en

Psoriasis mutations disrupt CA ...... T1-dependent NF-κB activation.

@nl

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Biochemical Journal

P1476

Psoriasis mutations disrupt CA ...... LT1-dependent NF-κB activation

@en

P2093

Ashavari Ghose

http://www.w3.org/2001/XMLSchema#string

Ashleigh Howes

http://www.w3.org/2001/XMLSchema#string

Felix Breyer

http://www.w3.org/2001/XMLSchema#string

Li Cao

http://www.w3.org/2001/XMLSchema#string

Paul A O'Sullivan

http://www.w3.org/2001/XMLSchema#string

Steven C Ley

http://www.w3.org/2001/XMLSchema#string

P2860

CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-kappa B

Phosphorylation of the CARMA1 linker controls NF-kappaB activation

Alternative splicing of CARMA2/CARD14 transcripts generates protein variants with differential effect on NF-κB activation and endoplasmic reticulum stress-induced cell death

Immunology of psoriasis

Activity-based probes for detection of active MALT1 paracaspase in immune cells and lymphomas

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

betaTrCP-mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932.

The protein kinase C-responsive inhibitory domain of CARD11 functions in NF-kappaB activation to regulate the association of multiple signaling cofactors that differentially depend on Bcl10 and MALT1 for association.

Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis.

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.

P304

1759-1768

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scholarly article

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10.1042/BCJ20160270

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P433

12

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473

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Anne M. Bowcock

Daniel Krappmann

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2016-04-12T00:00:00Z

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27071417

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5810350

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