betaTrCP-mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932.
about
Fbx7 functions in the SCF complex regulating Cdk1-cyclin B-phosphorylated hepatoma up-regulated protein (HURP) proteolysis by a proline-rich regionABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stabilityNF-kappaB1 p105 negatively regulates TPL-2 MEK kinase activityProstaglandin E receptor type 4-associated protein interacts directly with NF-kappaB1 and attenuates macrophage activationRegulation of the discs large tumor suppressor by a phosphorylation-dependent interaction with the beta-TrCP ubiquitin ligase receptorDeregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancerSilencing of both beta-TrCP1 and HOS (beta-TrCP2) is required to suppress human immunodeficiency virus type 1 Vpu-mediated CD4 down-modulationThe Ubiquitination of NF-κB Subunits in the Control of TranscriptionThe Regulation of NF-κB Subunits by PhosphorylationNF-κB, the first quarter-century: remarkable progress and outstanding questionsGSK3β and the control of infectious bacterial diseasesNF-κB Pathways in the Pathogenesis of Multiple Sclerosis and the Therapeutic ImplicationsPathogenesis of colorectal carcinoma and therapeutic implications: the roles of the ubiquitin-proteasome system and Cox-2Ubiquitination and degradation of the inhibitors of NF-kappaBRegulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinaseSonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradationRole of F-box protein betaTrcp1 in mammary gland development and tumorigenesisABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responsesFunctional regulation of the epithelial Na+ channel by IkappaB kinase-beta occurs via phosphorylation of the ubiquitin ligase Nedd4-2Point mutations in the tumor suppressor Smad4/DPC4 enhance its phosphorylation by GSK3 and reversibly inactivate TGF-β signalingAssociations Among -TrCP, an E3 Ubiquitin Ligase Receptor, -Catenin, and NF- B in Colorectal CancerG-protein-coupled-receptor kinases mediate TNFα-induced NFκB signalling via direct interaction with and phosphorylation of IκBα.Deletion analysis of BMI1 oncoprotein identifies its negative regulatory domainPost-translational modifications of exosomal proteins.EVM005: an ectromelia-encoded protein with dual roles in NF-κB inhibition and virulenceNfkb1 inhibits LPS-induced IFN-β and IL-12 p40 production in macrophages by distinct mechanisms.Tumor necrosis factor-{alpha} suppresses angiotensinogen expression through formation of a p50/p50 homodimer in human renal proximal tubular cells.IKK-induced NF-κB1 p105 proteolysis is critical for B cell antibody responses to T cell-dependent antigen.Directed expression of the HIV-1 accessory protein Vpu in Drosophila fat-body cells inhibits Toll-dependent immune responses.Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation.Heterologous SUMO-2/3-ubiquitin chains optimize IκBα degradation and NF-κB activity.TLR and TNF-R1 activation of the MKK3/MKK6-p38α axis in macrophages is mediated by TPL-2 kinase.Poxvirus targeting of E3 ligase β-TrCP by molecular mimicry: a mechanism to inhibit NF-κB activation and promote immune evasion and virulence.NF-κB1 inhibits TLR-induced IFN-β production in macrophages through TPL-2-dependent ERK activationPhosphorylation of NF-kappaB p65 at Ser468 controls its COMMD1-dependent ubiquitination and target gene-specific proteasomal eliminationA unique insertion in STARD9's motor domain regulates its stabilitySCF(beta-TrCP1) controls Smad4 protein stability in pancreatic cancer cellsNF-κB signaling participates in both RANKL- and IL-4-induced macrophage fusion: receptor cross-talk leads to alterations in NF-κB pathways.The TRAF-associated protein TANK facilitates cross-talk within the IkappaB kinase family during Toll-like receptor signaling.SAG/ROC-SCF beta-TrCP E3 ubiquitin ligase promotes pro-caspase-3 degradation as a mechanism of apoptosis protection
P2860
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P2860
betaTrCP-mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
betaTrCP-mediated proteolysis ...... on of p105 serines 927 and 932
@nl
betaTrCP-mediated proteolysis ...... n of p105 serines 927 and 932.
@ast
betaTrCP-mediated proteolysis ...... n of p105 serines 927 and 932.
@en
type
label
betaTrCP-mediated proteolysis ...... on of p105 serines 927 and 932
@nl
betaTrCP-mediated proteolysis ...... n of p105 serines 927 and 932.
@ast
betaTrCP-mediated proteolysis ...... n of p105 serines 927 and 932.
@en
prefLabel
betaTrCP-mediated proteolysis ...... on of p105 serines 927 and 932
@nl
betaTrCP-mediated proteolysis ...... n of p105 serines 927 and 932.
@ast
betaTrCP-mediated proteolysis ...... n of p105 serines 927 and 932.
@en
P2093
P2860
P921
P3181
P1476
betaTrCP-mediated proteolysis ...... n of p105 serines 927 and 932.
@en
P2093
Andres Salmeron
Gregory Zvi Fischer
Hamish Allen
Julia Janzen
Steven C Ley
Sören Beinke
Valerie Lang
Yinon Ben-Neriah
P2860
P304
P3181
P356
10.1128/MCB.23.1.402-413.2003
P407
P577
2003-01-01T00:00:00Z