Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition. - Test2 - elhamkhani - TriplyDB

Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition.

Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition.

http://www.wikidata.org/entity/Q34541837

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MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.H3K4 Methyltransferase Activity Is Required for MLL4 Protein Stability.Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.Distinct functions of histone H3, lysine 4 methyltransferases in normal and malignant hematopoiesis.Histone H3 lysine 4 methyltransferase KMT2D.Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability.Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis.Identification of H3K4me1-associated proteins at mammalian enhancers.UTX-guided neural crest function underlies craniofacial features of Kabuki syndrome.The mixed lineage leukemia 4 (MLL4) methyltransferase complex is involved in transforming growth factor beta (TGF-β)-activated gene transcription.Chromatin modifying gene mutations in follicular lymphoma.The interplay of epigenetic marks during stem cell differentiation and development.An Mll4/COMPASS-Lsd1 epigenetic axis governs enhancer function and pluripotency transition in embryonic stem cells.KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis.Histone H3 lysine 4 monomethylation modulates long-range chromatin interactions at enhancers.Steering Against Wind: A New Network of NamiRNAs and Enhancers.A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription.Esrrb extinction triggers dismantling of naïve pluripotency and marks commitment to differentiation The Trithorax group protein dMLL3/4 instructs the assembly of the zygotic genome at fertilization Conservation of epigenetic regulation by the MLL3/4 tumour suppressor in planarian pluripotent stem cells

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Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition.

http://www.wikidata.org/entity/Q34541837

description

2016 nî lūn-bûn

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2016 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2016 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2016年の論文

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2016年学术文章

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2016年学术文章

@zh-cn

2016年学术文章

@zh-hans

2016年学术文章

@zh-my

2016年学术文章

@zh-sg

2016年學術文章

@yue

name

Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition.

@ast

Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition.

@en

Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition.

@nl

type

label

Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition.

@ast

Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition.

@en

Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition.

@nl

prefLabel

Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition.

@ast

Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition.

@en

Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition.

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PNAS.1606857113

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Proceedings of the National Academy of Sciences of the United States of America

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Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition.

@en

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Binbin Lai

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Chaochen Wang

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Chengyu Liu

http://www.w3.org/2001/XMLSchema#string

Lenan Zhuang

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Shiliyang Xu

http://www.w3.org/2001/XMLSchema#string

Weiqun Peng

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P2860

Embryonic stem cell differentiation: emergence of a new era in biology and medicine

Enhancer RNAs and regulated transcriptional programs

Hijacked in cancer: the KMT2 (MLL) family of methyltransferases

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

The selection and function of cell type-specific enhancers

Histone modifications at human enhancers reflect global cell-type-specific gene expression

Control of cell identity genes occurs in insulated neighborhoods in mammalian chromosomes

UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity

Super-enhancers in the control of cell identity and disease

The ground state of embryonic stem cell self-renewal

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11871-11876

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10.1073/PNAS.1606857113

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42

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113

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5081576

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