GPCR ligand-dendrimer (GLiDe) conjugates: future smart drugs? - Test2 - elhamkhani - TriplyDB

GPCR ligand-dendrimer (GLiDe) conjugates: future smart drugs?

GPCR ligand-dendrimer (GLiDe) conjugates: future smart drugs?

http://www.wikidata.org/entity/Q34548745

about

Programmable nanoscaffolds that control ligand display to a G-protein-coupled receptor in membranes to allow dissection of multivalent effects.Structure-based approaches to ligands for G-protein-coupled adenosine and P2Y receptors, from small molecules to nanoconjugates.Molecular probes for the A2A adenosine receptor based on a pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine scaffold GPCR ligand dendrimer (GLiDe) conjugates: adenosine receptor interactions of a series of multivalent xanthine antagonists Anti-ischemic effects of multivalent dendrimeric A₃ adenosine receptor agonists in cultured cardiomyocytes and in the isolated rat heart.Click modification in the N6 region of A3 adenosine receptor-selective carbocyclic nucleosides for dendrimeric tethering that preserves pharmacophore recognition.Drug conjugates—an emerging approach to treat breast cancer.

P2860

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P2860

GPCR ligand-dendrimer (GLiDe) conjugates: future smart drugs?

http://www.wikidata.org/entity/Q34548745

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

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name

GPCR ligand-dendrimer (GLiDe) conjugates: future smart drugs?

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GPCR ligand-dendrimer (GLiDe) conjugates: future smart drugs?

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GPCR ligand-dendrimer

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GPCR ligand-dendrimer (GLiDe) conjugates: future smart drugs?

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GPCR ligand-dendrimer (GLiDe) conjugates: future smart drugs?

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GPCR ligand-dendrimer

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GPCR ligand-dendrimer (GLiDe) conjugates: future smart drugs?

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GPCR ligand-dendrimer (GLiDe) conjugates: future smart drugs?

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GPCR ligand-dendrimer

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J.TIPS.2010.09.002

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Trends in Pharmacological Sciences

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GPCR ligand-dendrimer (GLiDe) conjugates: future smart drugs?

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Kenneth A Jacobson

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P2860

International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy

Adenosine receptors as therapeutic targets

Building a new conceptual framework for receptor heteromers

How many drug targets are there?

Nanocarriers as an emerging platform for cancer therapy

Structure-based discovery of novel chemotypes for adenosine A(2A) receptor antagonists.

Synthesis, characterization and stability of a luteinizing hormone-releasing hormone (LHRH)-functionalized poly(amidoamine) dendrimer conjugate.

PEGylated dendritic unimolecular micelles as versatile carriers for ligands of G protein-coupled receptors.

Structure-based discovery of A2A adenosine receptor ligands.

UDP-glucose acting at P2Y14 receptors is a mediator of mast cell degranulation

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575-579

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10.1016/J.TIPS.2010.09.002

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12

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20961625

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G protein-coupled receptor

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