Structure-based discovery of A2A adenosine receptor ligands.
about
Crystal structure-based virtual screening for fragment-like ligands of the human histamine H(1) receptorStructure-based discovery of opioid analgesics with reduced side effects.Diversity and modularity of G protein-coupled receptor structuresLarge-scale production and protein engineering of G protein-coupled receptors for structural studiesNew insights for drug design from the X-ray crystallographic structures of G-protein-coupled receptorsBiophysical Fragment Screening of the β 1 -Adrenergic Receptor: Identification of High Affinity Arylpiperazine Leads Using Structure-Based Drug DesignRecent developments in adenosine receptor ligands and their potential as novel drugsLigand pose and orientational sampling in molecular dockingStructural and energetic effects of A2A adenosine receptor mutations on agonist and antagonist bindingZINC 15--Ligand Discovery for EveryoneIn search of novel ligands using a structure-based approach: a case study on the adenosine A2A receptorThe role of experimental and computational structural approaches in 7TM drug discovery.Compound activity prediction using models of binding pockets or ligand properties in 3D.Docking Screens for Novel Ligands Conferring New Biology.Structure-function of the G protein-coupled receptor superfamily.Ligand discovery from a dopamine D3 receptor homology model and crystal structureStructure-Based Discovery of New Antagonist and Biased Agonist Chemotypes for the Kappa Opioid ReceptorPharmacochemistry of the platelet purinergic receptors.Substructure-based virtual screening for adenosine A2A receptor ligands.Analysis of structure-based virtual screening studies and characterization of identified active compounds.Structure based prediction of subtype-selectivity for adenosine receptor antagonistsDiscovery of a novel selective kappa-opioid receptor agonist using crystal structure-based virtual screening.Limits of ligand selectivity from docking to models: in silico screening for A(1) adenosine receptor antagonistsEvaluation of Phytocannabinoids from High Potency Cannabis sativa using In Vitro Bioassays to Determine Structure-Activity Relationships for Cannabinoid Receptor 1 and Cannabinoid Receptor 2GPCR ligand-dendrimer (GLiDe) conjugates: future smart drugs?Structural Analysis of Chemokine Receptor-Ligand Interactions.Docking-based virtual screening for ligands of G protein-coupled receptors: not only crystal structures but also in silico models.Conformation guides molecular efficacy in docking screens of activated β-2 adrenergic G protein coupled receptorStructure-based approaches to ligands for G-protein-coupled adenosine and P2Y receptors, from small molecules to nanoconjugates.International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and classification of adenosine receptors--an updateMolecular probes for the A2A adenosine receptor based on a pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine scaffoldStructure-based ligand discovery targeting orthosteric and allosteric pockets of dopamine receptors.Computational studies to predict or explain G protein coupled receptor polypharmacologyIn silico analysis of the binding of agonists and blockers to the β2-adrenergic receptor.Molecular docking screening using agonist-bound GPCR structures: probing the A2A adenosine receptor.John Daly Lecture: Structure-guided Drug Design for Adenosine and P2Y ReceptorsPocketome: an encyclopedia of small-molecule binding sites in 4DIn silico screening for agonists and blockers of the β(2) adrenergic receptor: implications of inactive and activated state structuresSimbios: an NIH national center for physics-based simulation of biological structures.Structure-based ligand discovery for the protein-protein interface of chemokine receptor CXCR4
P2860
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P2860
Structure-based discovery of A2A adenosine receptor ligands.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Structure-based discovery of A2A adenosine receptor ligands.
@ast
Structure-based discovery of A2A adenosine receptor ligands.
@en
Structure-based discovery of A2A adenosine receptor ligands.
@nl
type
label
Structure-based discovery of A2A adenosine receptor ligands.
@ast
Structure-based discovery of A2A adenosine receptor ligands.
@en
Structure-based discovery of A2A adenosine receptor ligands.
@nl
prefLabel
Structure-based discovery of A2A adenosine receptor ligands.
@ast
Structure-based discovery of A2A adenosine receptor ligands.
@en
Structure-based discovery of A2A adenosine receptor ligands.
@nl
P2860
P50
P356
P1476
Structure-based discovery of A2A adenosine receptor ligands.
@en
P2093
P2860
P304
P356
10.1021/JM100240H
P407
P577
2010-05-01T00:00:00Z