Functional targeting of the MUC1 oncogene in human cancers
about
Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling)Immunogenic targets for specific immunotherapy in multiple myelomaIntracellular Targeting of the Oncogenic MUC1-C Protein with a Novel GO-203 Nanoparticle FormulationCharacterization of the MUC1-C Cytoplasmic Domain as a Cancer TargetDeletion of atbf1/zfhx3 in mouse prostate causes neoplastic lesions, likely by attenuation of membrane and secretory proteins and multiple signaling pathways.Interactions between MUC1 and p120 catenin regulate dynamic features of cell adhesion, motility, and metastasisTargeting MUC1-C is synergistic with bortezomib in downregulating TIGAR and inducing ROS-mediated myeloma cell death.MUC1-C activates BMI1 in human cancer cells.Intrinsic mitochondrial membrane potential and associated tumor phenotype are independent of MUC1 over-expression.MUCIN 1 ONCOPROTEIN EXPRESSION IS SUPPRESSED BY THE miR-125b ONCOMIRMUC1 regulates epithelial inflammation and apoptosis by PolyI:C through inhibition of Toll/IL-1 receptor-domain-containing adapter-inducing IFN-β (TRIF) recruitment to Toll-like receptor 3.MUC1-C confers EMT and KRAS independence in mutant KRAS lung cancer cellsDependence on the MUC1-C oncoprotein in non-small cell lung cancer cells.MUC1-C Induces the LIN28B→LET-7→HMGA2 Axis to Regulate Self-Renewal in NSCLCAutoantibodies to aberrantly glycosylated MUC1 in early stage breast cancer are associated with a better prognosis.The MUC1-C oncoprotein as a target in hematologic malignancies.Transmembrane mucins as novel therapeutic targetsUp-regulation of C1GALT1 promotes breast cancer cell growth through MUC1-C signaling pathwayA monoclonal antibody against the oncogenic mucin 1 cytoplasmic domainMucin 1 gene silencing inhibits the growth of SMMC-7721 human hepatoma cells through Bax-mediated mitochondrial and caspase-8-mediated death receptor apoptotic pathwaysMUC1-C oncoprotein confers androgen-independent growth of human prostate cancer cells.CCL21-CCR7 promotes the lymph node metastasis of esophageal squamous cell carcinoma by up-regulating MUC1.Inhibition of MUC1-C Suppresses MYC Expression and Attenuates Malignant Growth in KRAS Mutant Lung Adenocarcinomas.MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches.MUC1-C Stabilizes MCL-1 in the Oxidative Stress Response of Triple-Negative Breast Cancer Cells to BCL-2 Inhibitors.Combining T-cell immunotherapy and anti-androgen therapy for prostate cancer.MUC1 immunotherapy.The role of cancer-associated myofibroblasts in intrahepatic cholangiocarcinoma.MUC1-specific cytotoxic T lymphocytes in cancer therapy: induction and challenge.Role of integrin-linked kinase in regulating the protein stability of the MUC1-C oncoprotein in pancreatic cancer cells.Lewis(y) antigen promotes the progression of epithelial ovarian cancer by stimulating MUC1 expression.MUC1 in hematological malignancies.Reflections on MUC1 glycoprotein: the hidden potential of isoforms in carcinogenesis.Identification and characterization of agonist epitopes of the MUC1-C oncoprotein.Cytotoxic effects of bromelain in human gastrointestinal carcinoma cell lines (MKN45, KATO-III, HT29-5F12, and HT29-5M21).MUC1-C Oncoprotein Integrates a Program of EMT, Epigenetic Reprogramming and Immune Evasion in Human Carcinomas.Overexpression of MUC1 enhances proangiogenic activity of non-small-cell lung cancer cells through activation of Akt and extracellular signal-regulated kinase pathways.MUC1 is upregulated in advanced prostate cancer and is an independent prognostic factor.MUC1-C integrates PD-L1 induction with repression of immune effectors in non-small-cell lung cancer.MUC1-C activates EZH2 expression and function in human cancer cells.
P2860
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P2860
Functional targeting of the MUC1 oncogene in human cancers
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Functional targeting of the MUC1 oncogene in human cancers
@ast
Functional targeting of the MUC1 oncogene in human cancers
@en
Functional targeting of the MUC1 oncogene in human cancers
@nl
type
label
Functional targeting of the MUC1 oncogene in human cancers
@ast
Functional targeting of the MUC1 oncogene in human cancers
@en
Functional targeting of the MUC1 oncogene in human cancers
@nl
prefLabel
Functional targeting of the MUC1 oncogene in human cancers
@ast
Functional targeting of the MUC1 oncogene in human cancers
@en
Functional targeting of the MUC1 oncogene in human cancers
@nl
P2860
P356
P1476
Functional targeting of the MUC1 oncogene in human cancers
@en
P2093
Donald W Kufe
P2860
P304
P356
10.4161/CBT.8.13.8844
P577
2009-07-27T00:00:00Z