TMEM106B is associated with frontotemporal lobar degeneration in a clinically diagnosed patient cohort - Test2 - elhamkhani - TriplyDB

TMEM106B is associated with frontotemporal lobar degeneration in a clinically diagnosed patient cohort

TMEM106B is associated with frontotemporal lobar degeneration in a clinically diagnosed patient cohort

http://www.wikidata.org/entity/Q34605483

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The FTLD risk factor TMEM106B and MAP6 control dendritic trafficking of lysosomes The genetics and neuropathology of frontotemporal lobar degeneration Frontotemporal Lobar Degeneration and MicroRNAs Phenotypic Heterogeneity of Monogenic Frontotemporal Dementia The epidemiology of frontotemporal dementia Mechanisms of granulin deficiency: lessons from cellular and animal models Lysosome size, motility and stress response regulated by fronto-temporal dementia modifier TMEM106B TMEM106B expression is reduced in Alzheimer's disease brains Regulated intramembrane proteolysis of the frontotemporal lobar degeneration risk factor, TMEM106B, by signal peptide peptidase-like 2a (SPPL2a).C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis Transmembrane protein 106A is silenced by promoter region hypermethylation and suppresses gastric cancer growth by inducing apoptosis Brain distribution of dipeptide repeat proteins in frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72 Genome-wide association studies in neurology.The TMEM106B locus and TDP-43 pathology in older persons without FTLD Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine.TMEM106B a novel risk factor for frontotemporal lobar degeneration Membrane orientation and subcellular localization of transmembrane protein 106B (TMEM106B), a major risk factor for frontotemporal lobar degeneration.Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology.TMEM106B, the risk gene for frontotemporal dementia, is regulated by the microRNA-132/212 cluster and affects progranulin pathways.TMEM106B, a frontotemporal lobar dementia (FTLD) modifier, associates with FTD-3-linked CHMP2B, a complex of ESCRT-III.The molecular basis of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum Advances in understanding the molecular basis of frontotemporal dementia.TMEM106B p.T185S regulates TMEM106B protein levels: implications for frontotemporal dementia.Expression of TMEM106B, the frontotemporal lobar degeneration-associated protein, in normal and diseased human brain.Promoter DNA methylation regulates progranulin expression and is altered in FTLD.Elevated TMEM106B levels exaggerate lipofuscin accumulation and lysosomal dysfunction in aged mice with progranulin deficiency TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia.TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions.Human genetics as a tool to identify progranulin regulators.Frontotemporal lobar degeneration: current knowledge and future challenges.Genetics of FTLD: overview and what else we can expect from genetic studies.TiME for TMEM106B The clinical spectrum of sporadic and familial forms of frontotemporal dementia.What we know about TMEM106B in neurodegeneration.Molecular Genetics of Neurodegenerative Dementias.Circulating progranulin as a biomarker for neurodegenerative diseases The Lysosomal Trafficking Transmembrane Protein 106B Is Linked to Cell Death.The frontotemporal lobar degeneration risk factor, TMEM106B, regulates lysosomal morphology and function.TMEM106B and APOE polymorphisms interact to confer risk for late-onset Alzheimer's disease in Han Chinese.A Dementia-Associated Risk Variant near TMEM106B Alters Chromatin Architecture and Gene Expression.

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P2860

TMEM106B is associated with frontotemporal lobar degeneration in a clinically diagnosed patient cohort

http://www.wikidata.org/entity/Q34605483

description

2011 nî lūn-bûn

@nan

2011 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

@zh-hk

2011年論文

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2011年論文

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2011年论文

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name

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TMEM106B is associated with fr ...... cally diagnosed patient cohort

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type

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TMEM106B is associated with fr ...... cally diagnosed patient cohort

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TMEM106B is associated with fr ...... cally diagnosed patient cohort

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TMEM106B is associated with fr ...... cally diagnosed patient cohort

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prefLabel

TMEM106B is associated with fr ...... cally diagnosed patient cohort

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TMEM106B is associated with fr ...... cally diagnosed patient cohort

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TMEM106B is associated with fr ...... cally diagnosed patient cohort

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Geert Joris

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Jolien Brys

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Karin Peeters

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Marc Cruts

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Maria Mattheijssens

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Marleen Van den Broeck

http://www.w3.org/2001/XMLSchema#string

Patrick Cras

http://www.w3.org/2001/XMLSchema#string

Peter P De Deyn

http://www.w3.org/2001/XMLSchema#string

Tim Van Langenhove

http://www.w3.org/2001/XMLSchema#string

P2860

Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

PLINK: a tool set for whole-genome association and population-based linkage analyses

Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell lines

Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria

Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits

Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein

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808-815

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scholarly article

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10.1093/BRAIN/AWR007

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P433

Pt 3

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134

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Christine Van Broeckhoven

Kristel Sleegers

Julie van der Zee

Rik Vandenberghe

Patrick Santens

Sebastiaan Engelborghs

Gernot Kleinberger

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2011-03-01T00:00:00Z

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50214727

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21354975

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3044834

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