TMEM106B is associated with frontotemporal lobar degeneration in a clinically diagnosed patient cohort
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The FTLD risk factor TMEM106B and MAP6 control dendritic trafficking of lysosomesThe genetics and neuropathology of frontotemporal lobar degenerationFrontotemporal Lobar Degeneration and MicroRNAsPhenotypic Heterogeneity of Monogenic Frontotemporal DementiaThe epidemiology of frontotemporal dementiaMechanisms of granulin deficiency: lessons from cellular and animal modelsLysosome size, motility and stress response regulated by fronto-temporal dementia modifier TMEM106BTMEM106B expression is reduced in Alzheimer's disease brainsRegulated intramembrane proteolysis of the frontotemporal lobar degeneration risk factor, TMEM106B, by signal peptide peptidase-like 2a (SPPL2a).C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysisTransmembrane protein 106A is silenced by promoter region hypermethylation and suppresses gastric cancer growth by inducing apoptosisBrain distribution of dipeptide repeat proteins in frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72Genome-wide association studies in neurology.The TMEM106B locus and TDP-43 pathology in older persons without FTLDFrontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine.TMEM106B a novel risk factor for frontotemporal lobar degenerationMembrane orientation and subcellular localization of transmembrane protein 106B (TMEM106B), a major risk factor for frontotemporal lobar degeneration.Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology.TMEM106B, the risk gene for frontotemporal dementia, is regulated by the microRNA-132/212 cluster and affects progranulin pathways.TMEM106B, a frontotemporal lobar dementia (FTLD) modifier, associates with FTD-3-linked CHMP2B, a complex of ESCRT-III.The molecular basis of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrumAdvances in understanding the molecular basis of frontotemporal dementia.TMEM106B p.T185S regulates TMEM106B protein levels: implications for frontotemporal dementia.Expression of TMEM106B, the frontotemporal lobar degeneration-associated protein, in normal and diseased human brain.Promoter DNA methylation regulates progranulin expression and is altered in FTLD.Elevated TMEM106B levels exaggerate lipofuscin accumulation and lysosomal dysfunction in aged mice with progranulin deficiencyTMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia.TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions.Human genetics as a tool to identify progranulin regulators.Frontotemporal lobar degeneration: current knowledge and future challenges.Genetics of FTLD: overview and what else we can expect from genetic studies.TiME for TMEM106BThe clinical spectrum of sporadic and familial forms of frontotemporal dementia.What we know about TMEM106B in neurodegeneration.Molecular Genetics of Neurodegenerative Dementias.Circulating progranulin as a biomarker for neurodegenerative diseasesThe Lysosomal Trafficking Transmembrane Protein 106B Is Linked to Cell Death.The frontotemporal lobar degeneration risk factor, TMEM106B, regulates lysosomal morphology and function.TMEM106B and APOE polymorphisms interact to confer risk for late-onset Alzheimer's disease in Han Chinese.A Dementia-Associated Risk Variant near TMEM106B Alters Chromatin Architecture and Gene Expression.
P2860
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P2860
TMEM106B is associated with frontotemporal lobar degeneration in a clinically diagnosed patient cohort
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
TMEM106B is associated with fr ...... cally diagnosed patient cohort
@ast
TMEM106B is associated with fr ...... cally diagnosed patient cohort
@en
TMEM106B is associated with fr ...... cally diagnosed patient cohort
@nl
type
label
TMEM106B is associated with fr ...... cally diagnosed patient cohort
@ast
TMEM106B is associated with fr ...... cally diagnosed patient cohort
@en
TMEM106B is associated with fr ...... cally diagnosed patient cohort
@nl
prefLabel
TMEM106B is associated with fr ...... cally diagnosed patient cohort
@ast
TMEM106B is associated with fr ...... cally diagnosed patient cohort
@en
TMEM106B is associated with fr ...... cally diagnosed patient cohort
@nl
P2093
P2860
P50
P356
P1433
P1476
TMEM106B is associated with fr ...... cally diagnosed patient cohort
@en
P2093
Geert Joris
Jolien Brys
Karin Peeters
Marc Cruts
Maria Mattheijssens
Marleen Van den Broeck
Patrick Cras
Peter P De Deyn
Tim Van Langenhove
P2860
P304
P356
10.1093/BRAIN/AWR007
P407
P50
P577
2011-03-01T00:00:00Z