CLL cells respond to B-Cell receptor stimulation with a microRNA/mRNA signature associated with MYC activation and cell cycle progression

CLL cells respond to B-Cell receptor stimulation with a microRNA/mRNA signature associated with MYC activation and cell cycle progression

Item
http://www.wikidata.org/entity/Q34656369
Clustering of Expression Data in Chronic Lymphocytic Leukemia Reveals New Molecular Subdivisions.Stimulation of the B-cell receptor activates the JAK2/STAT3 signaling pathway in chronic lymphocytic leukemia cells.Higher gene expression variability in the more aggressive subtype of chronic lymphocytic leukemia.Lipoprotein lipase SNPs rs13702 and rs301 correlate with clinical outcome in chronic lymphocytic leukemia patients.The microRNA-212/132 cluster regulates B cell development by targeting Sox4.The SIRT1/TP53 axis is activated upon B-cell receptor triggering via miR-132 up-regulation in chronic lymphocytic leukemia cells.Mimicking the tumour microenvironment of chronic lymphocytic leukaemia in vitro critically depends on the type of B-cell receptor stimulation.Pro-apoptotic TP53 homolog TAp63 is repressed via epigenetic silencing and B-cell receptor signalling in chronic lymphocytic leukaemia.Myc enhances B-cell receptor signaling in precancerous B cells and confers resistance to Btk inhibitionmiRNAs in B Cell Development and Lymphomagenesis.Increased chronic lymphocytic leukemia proliferation upon IgM stimulation is sustained by the upregulation of miR-132 and miR-212.Extracellular vesicles of bone marrow stromal cells rescue chronic lymphocytic leukemia B cells from apoptosis, enhance their migration and induce gene expression modifications.Ibrutinib downregulates a subset of miRNA leading to upregulation of tumor suppressors and inhibition of cell proliferation in chronic lymphocytic leukemia.Climate smart agriculture, farm household typologies and food security: An ex-ante assessment from Eastern India.MicroRNA-212/ABCG2-axis contributes to development of imatinib-resistance in leukemic cells.Expression of ZAP70 in chronic lymphocytic leukaemia activates NF-κB signalling.MIR21 is differentially expressed in the lymphoid tissue and modulated by stromal signalling in chronic lymphocytic leukaemia.
P2860

CLL cells respond to B-Cell receptor stimulation with a microRNA/mRNA signature associated with MYC activation and cell cycle progression

Item
http://www.wikidata.org/entity/Q34656369
description
2013 nî lūn-bûn
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2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
CLL cells respond to B-Cell re ...... ion and cell cycle progression
@ast
CLL cells respond to B-Cell re ...... ion and cell cycle progression
@en
CLL cells respond to B-Cell re ...... ion and cell cycle progression
@nl
type
label
CLL cells respond to B-Cell re ...... ion and cell cycle progression
@ast
CLL cells respond to B-Cell re ...... ion and cell cycle progression
@en
CLL cells respond to B-Cell re ...... ion and cell cycle progression
@nl
prefLabel
CLL cells respond to B-Cell re ...... ion and cell cycle progression
@ast
CLL cells respond to B-Cell re ...... ion and cell cycle progression
@en
CLL cells respond to B-Cell re ...... ion and cell cycle progression
@nl
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CLL cells respond to B-Cell re ...... ion and cell cycle progression
@en
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P31
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10.1371/JOURNAL.PONE.0060275
P407
P433
P478
P50
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P5875
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