The synthesis and biological activity of pentafluorosulfanyl analogs of fluoxetine, fenfluramine, and norfenfluramine.
about
Design and generation of highly diverse fluorinated fragment libraries and their efficient screening with improved (19) F NMR methodology.Pentafluorosulfanyl-containing flufenamic acid analogs: Syntheses, properties and biological activitiesRecent advances in fluorination techniques and their anticipated impact on drug metabolism and toxicity.Application of the Pentafluorosulfanyl Group as a Bioisosteric Replacement.Microbial degradation of fluorinated drugs: biochemical pathways, impacts on the environment and potential applications.Use of Fluorinated Functionality in Enzyme Inhibitor Development: Mechanistic and Analytical AdvantagesEvaluation of tert-butyl isosteres: case studies of physicochemical and pharmacokinetic properties, efficacies, and activities.Synthesis of Phthalocyanines with a Pentafluorosulfanyl Substituent at Peripheral Positions.Synthesis and reactivity of aliphatic sulfur pentafluorides from substituted (pentafluorosulfanyl)benzenes.Synthesis and biological evaluation of the first pentafluorosulfanyl analogs of mefloquine.Microbial biotransformation of aryl sulfanylpentafluorides.S-F and S-C activation of SF6 and SF5 derivatives at rhodium: conversion of SF6 into H2S.SF5-Pyridylaryl-λ3-iodonium salts and their utility as electrophilic reagents to access SF5-pyridine derivatives in the late-stage of synthesis.Silver-induced self-immolative Cl-F exchange fluorination of arylsulfur chlorotetrafluorides: synthesis of arylsulfur pentafluorides.Allosteric agonists of the calcium receptor (CaR): fluorine and SF5 analogues of cinacalcet.IF5 affects the final stage of the Cl-F exchange fluorination in the synthesis of pentafluoro-λ6-sulfanyl-pyridines, pyrimidines and benzenes with electron-withdrawing substituents.Palladium-mediated borylation of pentafluorosulfanyl functionalized compounds: the crucial role of metal fluorido complexes.Simultaneous introduction of trifluoromethyl and λ(6)-pentafluorosulfanyl substituents using F5S-C≡C-CF3 as a dienophile.Racemic and enantioselective metal-catalyzed synthesis of SF5-containing diarylmethanols.Preparations of SF(5)- and CF(3)-substituted arenes utilizing the 7-oxabicyclo[2.2.1]hept-2-ene synthones.An eccentric rod-like linear connection of two heterocycles: synthesis of pyridine trans-tetrafluoro-λ6-sulfanyl triazoles.
P2860
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P2860
The synthesis and biological activity of pentafluorosulfanyl analogs of fluoxetine, fenfluramine, and norfenfluramine.
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The synthesis and biological a ...... luramine, and norfenfluramine.
@ast
The synthesis and biological a ...... luramine, and norfenfluramine.
@en
The synthesis and biological a ...... luramine, and norfenfluramine.
@nl
type
label
The synthesis and biological a ...... luramine, and norfenfluramine.
@ast
The synthesis and biological a ...... luramine, and norfenfluramine.
@en
The synthesis and biological a ...... luramine, and norfenfluramine.
@nl
prefLabel
The synthesis and biological a ...... luramine, and norfenfluramine.
@ast
The synthesis and biological a ...... luramine, and norfenfluramine.
@en
The synthesis and biological a ...... luramine, and norfenfluramine.
@nl
P1476
The synthesis and biological a ...... luramine, and norfenfluramine.
@en
P2093
Dong Sung Lim
John T Welch
P304
P356
10.1016/J.BMC.2007.08.012
P407
P577
2007-08-15T00:00:00Z