Evaluation of tert-butyl isosteres: case studies of physicochemical and pharmacokinetic properties, efficacies, and activities.
about
Derivatives of Procaspase-Activating Compound 1 (PAC-1) and their Anticancer Activities.Structure-Activity Study of Bioisosteric Trifluoromethyl and Pentafluorosulfanyl Indole Inhibitors of the AAA ATPase p97.Organic chemistry. Strain-release amination.Strain-Release Heteroatom Functionalization: Development, Scope, and Stereospecificity.Application of the Pentafluorosulfanyl Group as a Bioisosteric Replacement.Recent Progress Toward the Synthesis of Trifluoromethyl- and Difluoromethyl-Substituted Cyclopropanes.Stereochemistry and biological activity of chlorinated lipids: a study of danicalipin A and selected diastereomers.Trifluoromethyl Oxetanes: Synthesis and Evaluation as a tert-Butyl Isostere.Improving Nonspecific Binding and Solubility: Bicycloalkyl Groups and Cubanes as para-Phenyl Bioisosteres.Catalytic Enantioselective Synthesis of Highly Functionalized Difluoromethylated Cyclopropanes.Formation of α-SF5-Enolate Enables Preparation of 3-SF5-Quinolin-2-ones, 3-SF5-Quinolines, and 3-SF5-Pyridin-2-ones: Evaluation of their Physicochemical Properties.Ni/Ir-Catalyzed Photoredox Decarboxylative Coupling of S-Substituted Thiolactic Acids with Heteroaryl Bromides: Short Synthesis of Sulfoxaflor and Its SF5 Analog.Synthesis of Bicyclo[1.1.1]pentane Bioisosteres of Internal Alkynes and para-Disubstituted Benzenes from [1.1.1]Propellane.Silver-induced self-immolative Cl-F exchange fluorination of arylsulfur chlorotetrafluorides: synthesis of arylsulfur pentafluorides.IF5 affects the final stage of the Cl-F exchange fluorination in the synthesis of pentafluoro-λ6-sulfanyl-pyridines, pyrimidines and benzenes with electron-withdrawing substituents.Novel Toxoplasma gondii inhibitor chemotypes.Racemic and enantioselective metal-catalyzed synthesis of SF5-containing diarylmethanols.Synthesis and applications of highly functionalized 1-halo-3-substituted bicyclo[1.1.1]pentanes.
P2860
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P2860
Evaluation of tert-butyl isosteres: case studies of physicochemical and pharmacokinetic properties, efficacies, and activities.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Evaluation of tert-butyl isost ...... s, efficacies, and activities.
@en
type
label
Evaluation of tert-butyl isost ...... s, efficacies, and activities.
@en
prefLabel
Evaluation of tert-butyl isost ...... s, efficacies, and activities.
@en
P2093
P2860
P356
P1433
P1476
Evaluation of tert-butyl isost ...... s, efficacies, and activities.
@en
P2093
Bernd T Wolfstädter
Jean-Marc Plancher
John Gatfield
P2860
P304
P356
10.1002/CMDC.201402502
P577
2015-01-28T00:00:00Z