Alpha-synuclein sequesters Dnmt1 from the nucleus: a novel mechanism for epigenetic alterations in Lewy body diseases - Test2 - elhamkhani - TriplyDB

Alpha-synuclein sequesters Dnmt1 from the nucleus: a novel mechanism for epigenetic alterations in Lewy body diseases

Alpha-synuclein sequesters Dnmt1 from the nucleus: a novel mechanism for epigenetic alterations in Lewy body diseases

http://www.wikidata.org/entity/Q34685028

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Mercury biomarkers and DNA methylation among Michigan dental professionals SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities Potential Role of Epigenetic Mechanism in Manganese Induced Neurotoxicity Computational Modelling Approaches on Epigenetic Factors in Neurodegenerative and Autoimmune Diseases and Their Mechanistic Analysis Environmental pollutants as risk factors for neurodegenerative disorders: Alzheimer and Parkinson diseases Epigenetic landscape of Parkinson's disease: emerging role in disease mechanisms and therapeutic modalities Transcriptomic Profiling of Extracellular RNAs Present in Cerebrospinal Fluid Identifies Differentially Expressed Transcripts in Parkinson's Disease.Amyloid β: one of three danger-associated molecules that are secondary inducers of the proinflammatory cytokines that mediate Alzheimer's disease Epigenetic DNA Methylation Profiling with MSRE: A Quantitative NGS Approach Using a Parkinson's Disease Test Case Epigenetic alterations in the brain associated with HIV-1 infection and methamphetamine dependence Selective binding of nuclear alpha-synuclein to the PGC1alpha promoter under conditions of oxidative stress may contribute to losses in mitochondrial function: implications for Parkinson's disease CpG and Non-CpG Methylation in Epigenetic Gene Regulation and Brain Function A DNA methylation fingerprint of 1628 human samples.Increased epigenetic age and granulocyte counts in the blood of Parkinson's disease patients Reduced RAN expression and disrupted transport between cytoplasm and nucleus; a key event in Alzheimer's disease pathophysiology.Use of epigenetic drugs in disease: an overview.NURR1 in Parkinson disease--from pathogenesis to therapeutic potential.Progressive aggregation of alpha-synuclein and selective degeneration of lewy inclusion-bearing neurons in a mouse model of parkinsonism.Dissociable deficits of executive function caused by gestational adversity are linked to specific transcriptional changes in the prefrontal cortex.Advances in epigenetics and epigenomics for neurodegenerative diseases.Combined Nurr1 and Foxa2 roles in the therapy of Parkinson's disease.Blood transcriptomics of drug-naïve sporadic Parkinson's disease patients.DNA methylation dynamics in plants and mammals: overview of regulation and dysregulation.Neurorestoration induced by the HDAC inhibitor sodium valproate in the lactacystin model of Parkinson's is associated with histone acetylation and up-regulation of neurotrophic factors.α-Synuclein induces alterations in adult neurogenesis in Parkinson disease models via p53-mediated repression of Notch1.Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients.Chromatin deregulation in disease.Epigenetic mechanisms in neurological disease Aberrant intracellular localization of H3k4me3 demonstrates an early epigenetic phenomenon in Alzheimer's disease.Up-regulation of SNCA gene expression: implications to synucleinopathies Meta-Analysis of Differential Connectivity in Gene Co-Expression Networks in Multiple Sclerosis.Epigenetic DNA Demethylation Causes Inner Ear Stem Cell Differentiation into Hair Cell-Like Cells DNA modifications and neurological disorders.DNA methylation, a hand behind neurodegenerative diseases.Distinctive patterns of DNA methylation associated with Parkinson disease: identification of concordant epigenetic changes in brain and peripheral blood leukocytes.Epigenetic determinants of healthy and diseased brain aging and cognition.Hypomethylation of intron1 of α-synuclein gene does not correlate with Parkinson's disease.LINE-1 DNA methylation, smoking and risk of Parkinson's disease Opening up the DNA methylome of dementia α-Synuclein in Parkinson's disease.

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P2860

Alpha-synuclein sequesters Dnmt1 from the nucleus: a novel mechanism for epigenetic alterations in Lewy body diseases

http://www.wikidata.org/entity/Q34685028

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2011 nî lūn-bûn

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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2011年の論文

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Alpha-synuclein sequesters Dnm ...... erations in Lewy body diseases

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Alpha-synuclein sequesters Dnm ...... erations in Lewy body diseases

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Alpha-synuclein sequesters Dnm ...... erations in Lewy body diseases

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Alpha-synuclein sequesters Dnm ...... erations in Lewy body diseases

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Alpha-synuclein sequesters Dnm ...... erations in Lewy body diseases

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Alpha-synuclein sequesters Dnm ...... erations in Lewy body diseases

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Anthony Adame

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Brian Spencer

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Christina Patrick

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Elizabeth Coffee

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Paula Desplats

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Pruthul Patel

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Sarah Michael

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P2860

DNA methylation and memory formation

Alpha-synuclein in Lewy bodies

Functional roles for the striatal-enriched transcription factor, Bcl11b, in the control of striatal gene expression and transcriptional dysregulation in Huntington's disease

Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders

DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons.

Gene expression profiling of substantia nigra dopamine neurons: further insights into Parkinson's disease pathology.

Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases

CpG demethylation enhances alpha-synuclein expression and affects the pathogenesis of Parkinson's disease

Methylation regulates alpha-synuclein expression and is decreased in Parkinson's disease patients' brains.

Cortical Lewy body disease and Parkinson's disease dementia.

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9031-9037

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10.1074/JBC.C110.212589

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11

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286

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Eliezer Masliah

Edward Rockenstein

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2011-02-04T00:00:00Z

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21296890

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