The intracellular domain of sortilin interacts with amyloid precursor protein and regulates its lysosomal and lipid raft trafficking

The intracellular domain of sortilin interacts with amyloid precursor protein and regulates its lysosomal and lipid raft trafficking

Item
http://www.wikidata.org/entity/Q34737328
Sortilin mediates vascular calcification via its recruitment into extracellular vesiclesSortilin Fragments Deposit at Senile Plaques in Human CerebrumPAT1 inversely regulates the surface Amyloid Precursor Protein level in mouse primary neurons.Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other.Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing Aβ Generation and Amyloid Plaque Pathogenesis.Informatics Support for Basic Research in Biomedicine.Amyloid beta₁₋₄₂ (Aβ₄₂) up-regulates the expression of sortilin via the p75(NTR)/RhoA signaling pathway.Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA.Trafficking in Alzheimer's Disease: Modulation of APP Transport and Processing by the Transmembrane Proteins LRP1, SorLA, SorCS1c, Sortilin, and Calsyntenin.p75 neurotrophin receptor interacts with and promotes BACE1 localization in endosomes aggravating amyloidogenesis.Dysregulation of Neuronal Iron Homeostasis as an Alternative Unifying Effect of Mutations Causing Familial Alzheimer's Disease
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The intracellular domain of sortilin interacts with amyloid precursor protein and regulates its lysosomal and lipid raft trafficking

Item
http://www.wikidata.org/entity/Q34737328
description
2013 nî lūn-bûn
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2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2013 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
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2013年论文
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name
The intracellular domain of so ...... mal and lipid raft trafficking
@ast
The intracellular domain of so ...... mal and lipid raft trafficking
@en
The intracellular domain of so ...... mal and lipid raft trafficking
@nl
type
label
The intracellular domain of so ...... mal and lipid raft trafficking
@ast
The intracellular domain of so ...... mal and lipid raft trafficking
@en
The intracellular domain of so ...... mal and lipid raft trafficking
@nl
prefLabel
The intracellular domain of so ...... mal and lipid raft trafficking
@ast
The intracellular domain of so ...... mal and lipid raft trafficking
@en
The intracellular domain of so ...... mal and lipid raft trafficking
@nl
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The intracellular domain of so ...... mal and lipid raft trafficking
@en
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P2860
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10.1371/JOURNAL.PONE.0063049
P407
P433
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P50
P577
P5875
P698
P932