Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-gamma coactivator 1alpha.
about
Monoamine oxidases (MAO) in the pathogenesis of heart failure and ischemia/reperfusion injuryThioredoxin and ventricular remodelingMitochondrial biogenesis and dynamics in the developing and diseased heartMaternal cardiac metabolism in pregnancyUsing exercise to measure and modify cardiac functionNew insights into PGC-1 coactivators: redefining their role in the regulation of mitochondrial function and beyondPGC-1 proteins and heart failureFunctional O-GlcNAc modifications: implications in molecular regulation and pathophysiologyPathogenesis of target organ damage in hypertension: role of mitochondrial oxidative stressPGC-1/Spargel Counteracts High-Fat-Diet-Induced Obesity and Cardiac Lipotoxicity Downstream of TOR and Brummer ATGL Lipase.Cardiac-specific hexokinase 2 overexpression attenuates hypertrophy by increasing pentose phosphate pathway fluxPGC-1 alpha serine 570 phosphorylation and GCN5-mediated acetylation by angiotensin II drive catalase down-regulation and vascular hypertrophyCardiac lipin 1 expression is regulated by the peroxisome proliferator activated receptor γ coactivator 1α/estrogen related receptor axis.Cancer therapy-induced cardiotoxicity: basic mechanisms and potential cardioprotective therapies.Alpha1A-adrenergic receptor-directed autoimmunity induces left ventricular damage and diastolic dysfunction in rats.Low levels of physical activity increase metabolic responsiveness to cold in a rat (Rattus fuscipes).A role for peroxisome proliferator-activated receptor γ coactivator-1 in the control of mitochondrial dynamics during postnatal cardiac growthDisruption of sarcolemmal ATP-sensitive potassium channel activity impairs the cardiac response to systolic overload.Defective DNA replication impairs mitochondrial biogenesis in human failing heartsMaintaining PGC-1α expression following pressure overload-induced cardiac hypertrophy preserves angiogenesis but not contractile or mitochondrial function.Effects of aging on angiogenesis.Tom70 serves as a molecular switch to determine pathological cardiac hypertrophyInduction of PGC-1α expression can be detected in blood samples of patients with ST-segment elevation acute myocardial infarctionTelomere dysfunction induces metabolic and mitochondrial compromise.O-linked β-N-acetylglucosamine transferase is indispensable in the failing heart.Pathological role of serum- and glucocorticoid-regulated kinase 1 in adverse ventricular remodeling.Identification of the molecular basis of doxorubicin-induced cardiotoxicity.Promoting PGC-1α-driven mitochondrial biogenesis is detrimental in pressure-overloaded mouse hearts.PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection.Divergent mitochondrial biogenesis responses in human cardiomyopathyThe PGC-1 cascade as a therapeutic target for heart failureQiShenYiQi Pills, a Compound Chinese Medicine, Ameliorates Doxorubicin-Induced Myocardial Structure Damage and Cardiac Dysfunction in RatsAnalysis of skeletal muscle gene expression patterns and the impact of functional capacity in patients with systolic heart failure.Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heartGlucose metabolism and cardiac hypertrophymicroRNA-22 promotes heart failure through coordinate suppression of PPAR/ERR-nuclear hormone receptor transcription.Mitochondrial adaptations to physiological vs. pathological cardiac hypertrophy.Enhanced cardiac Akt/protein kinase B signaling contributes to pathological cardiac hypertrophy in part by impairing mitochondrial function via transcriptional repression of mitochondrion-targeted nuclear genes.High fat feeding in mice is insufficient to induce cardiac dysfunction and does not exacerbate heart failure.Toll-like receptor-mediated inflammatory signaling reprograms cardiac energy metabolism by repressing peroxisome proliferator-activated receptor γ coactivator-1 signaling.
P2860
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P2860
Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-gamma coactivator 1alpha.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Transverse aortic constriction ...... PPAR-gamma coactivator 1alpha.
@ast
Transverse aortic constriction ...... PPAR-gamma coactivator 1alpha.
@en
Transverse aortic constriction ...... PPAR-gamma coactivator 1alpha.
@nl
type
label
Transverse aortic constriction ...... PPAR-gamma coactivator 1alpha.
@ast
Transverse aortic constriction ...... PPAR-gamma coactivator 1alpha.
@en
Transverse aortic constriction ...... PPAR-gamma coactivator 1alpha.
@nl
prefLabel
Transverse aortic constriction ...... PPAR-gamma coactivator 1alpha.
@ast
Transverse aortic constriction ...... PPAR-gamma coactivator 1alpha.
@en
Transverse aortic constriction ...... PPAR-gamma coactivator 1alpha.
@nl
P2093
P2860
P356
P1476
Transverse aortic constriction ...... PPAR-gamma coactivator 1alpha.
@en
P2093
Anthony Rosenzweig
Mikhail Novikov
Sherry Chin
Yanhong Ma
Zoltan Arany
P2860
P304
10086-10091
P356
10.1073/PNAS.0603615103
P407
P577
2006-06-14T00:00:00Z