Molecular mechanism of pH sensing in KcsA potassium channels.
about
Stimulatory effect of xenobiotics on oxidative electron transport of chemolithotrophic nitrifying bacteria used as biosensing elementStructural mechanism of C-type inactivation in K(+) channelsRole of the KcsA channel cytoplasmic domain in pH-dependent gatingHuman Aquaporin-4 and Molecular Modeling: Historical Perspective and View to the FutureMechanism for selectivity-inactivation coupling in KcsA potassium channelsMolecular interactions involved in proton-dependent gating in KcsA potassium channelsHigh-resolution crystal structure of HA33 of botulinum neurotoxin type B progenitor toxin complexCooperative transition between open and closed conformations in potassium channelsConformational changes and slow dynamics through microsecond polarized atomistic molecular simulation of an integral Kv1.2 ion channelConsidering protonation as a posttranslational modification regulating protein structure and function.Design and characterization of a constitutively open KcsA.The open gate structure of the membrane-embedded KcsA potassium channel viewed from the cytoplasmic sideShape-Dependent Global Deformation Modes of Large Protein StructuresStructural basis underlying the dual gate properties of KcsAConformational dynamics in the selectivity filter of KcsA in response to potassium ion concentrationRegulation of ion channel function by the host lipid bilayer examined by a stopped-flow spectrofluorometric assay.Rearrangements in the KcsA cytoplasmic domain underlie its gating.Antiport mechanism for Cl(-)/H(+) in ClC-ec1 from normal-mode analysis.Potassium channel gating: not an open and shut case.Direct manipulation of a single potassium channel gate with an atomic force microscope probe.Potassium-selective block of barium permeation through single KcsA channelsNon-vesicular transfer of membrane proteins from nanoparticles to lipid bilayers.GCN4 enhances the stability of the pore domain of potassium channel KcsA.External Ba2+ block of the two-pore domain potassium channel TREK-1 defines conformational transition in its selectivity filter.Permeation and block of the Kv1.2 channel examined using brownian and molecular dynamics.Protonation state of E71 in KcsA and its role for channel collapse and inactivation.The Hydrophobic Effect Contributes to the Closed State of a Simplified Ion Channel through a Conserved Hydrophobic Patch at the Pore-Helix CrossingIon-binding properties of a K+ channel selectivity filter in different conformations.Perspectives on: conformational coupling in ion channels: thermodynamics of electromechanical coupling in voltage-gated ion channels.Filter gate closure inhibits ion but not water transport through potassium channelsFluorescence detection of the movement of single KcsA subunits reveals cooperativity.Conformational heterogeneity in closed and open states of the KcsA potassium channel in lipid bicelles.Transmembrane communication: general principles and lessons from the structure and function of the M2 proton channel, K⁺ channels, and integrin receptors.Preparation of uniformly isotope labeled KcsA for solid state NMR: expression, purification, reconstitution into liposomes and functional assay.Inhibition of K(Ca)2.2 and K(Ca)2.3 channel currents by protonation of outer pore histidine residues.Transmembrane allosteric coupling of the gates in a potassium channel.A KcsA/MloK1 chimeric ion channel has lipid-dependent ligand-binding energetics.Mechanism of electromechanical coupling in voltage-gated potassium channels.Being flexible: the voltage-controllable activation gate of kv channels.Residues in the H+ translocation site define the pKa for sugar binding to LacY.
P2860
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P2860
Molecular mechanism of pH sensing in KcsA potassium channels.
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Molecular mechanism of pH sensing in KcsA potassium channels.
@ast
Molecular mechanism of pH sensing in KcsA potassium channels.
@en
Molecular mechanism of pH sensing in KcsA potassium channels.
@nl
type
label
Molecular mechanism of pH sensing in KcsA potassium channels.
@ast
Molecular mechanism of pH sensing in KcsA potassium channels.
@en
Molecular mechanism of pH sensing in KcsA potassium channels.
@nl
prefLabel
Molecular mechanism of pH sensing in KcsA potassium channels.
@ast
Molecular mechanism of pH sensing in KcsA potassium channels.
@en
Molecular mechanism of pH sensing in KcsA potassium channels.
@nl
P2093
P2860
P356
P1476
Molecular mechanism of pH sensing in KcsA potassium channels.
@en
P2093
Ameer N Thompson
Crina M Nimigean
David J Posson
Pirooz V Parsa
P2860
P304
P356
10.1073/PNAS.0800873105
P407
P577
2008-04-28T00:00:00Z