Depletion of the cap-associated isoform of translation factor eIF4G induces germline apoptosis in C. elegans.
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Positive mRNA Translational Control in Germ Cells by Initiation Factor SelectivityThe translational regulators GCN-1 and ABCF-3 act together to promote apoptosis in C. elegansThe EIF4G1 gene and Parkinson's diseasePI3K/PTEN signaling in angiogenesis and tumorigenesisFunctional overlap between eIF4G isoforms in Saccharomyces cerevisiae.LIN-35/Rb causes starvation-induced germ cell apoptosis via CED-9/Bcl2 downregulation in Caenorhabditis elegans.A C. elegans eIF4E-family member upregulates translation at elevated temperatures of mRNAs encoding MSH-5 and other meiotic crossover proteins.eIF4F-like complexes formed by cap-binding homolog TbEIF4E5 with TbEIF4G1 or TbEIF4G2 are implicated in post-transcriptional regulation in Trypanosoma bruceiCap-independent translation promotes C. elegans germ cell apoptosis through Apaf-1/CED-4 in a caspase-dependent mechanismTrypanosoma brucei translation initiation factor homolog EIF4E6 forms a tripartite cytosolic complex with EIF4G5 and a capping enzyme homolog.Life span extension via eIF4G inhibition is mediated by posttranscriptional remodeling of stress response gene expression in C. elegans.On the Diversification of the Translation Apparatus across EukaryotesTranslational control of the oogenic program by components of OMA ribonucleoprotein particles in Caenorhabditis elegansInduction of cap-independent BiP (hsp-3) and Bcl-2 (ced-9) translation in response to eIF4G (IFG-1) depletion in C. elegansDegenerin channel activation causes caspase-mediated protein degradation and mitochondrial dysfunction in adult C. elegans muscleA germline-specific isoform of eIF4E (IFE-1) is required for efficient translation of stored mRNAs and maturation of both oocytes and sperm.Evolutionary changes in the Leishmania eIF4F complex involve variations in the eIF4E-eIF4G interactions.Reducing translation through eIF4G/IFG-1 improves survival under ER stress that depends on heat shock factor HSF-1 in Caenorhabditis elegans.Role of translation initiation factor 4G in lifespan regulation and age-related healthTranscriptome-wide studies uncover the diversity of modes of mRNA recruitment to eukaryotic ribosomes.Two related trypanosomatid eIF4G homologues have functional differences compatible with distinct roles during translation initiation.Phasing in on the cell cycle.eIF4G-an integrator of mRNA metabolism?Functional Interactions Between /S6K, /Notch, and Regulators of Fertility and Germline Stem Cell Maintenance
P2860
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P2860
Depletion of the cap-associated isoform of translation factor eIF4G induces germline apoptosis in C. elegans.
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Depletion of the cap-associate ...... mline apoptosis in C. elegans.
@ast
Depletion of the cap-associate ...... mline apoptosis in C. elegans.
@en
Depletion of the cap-associate ...... mline apoptosis in C. elegans.
@nl
type
label
Depletion of the cap-associate ...... mline apoptosis in C. elegans.
@ast
Depletion of the cap-associate ...... mline apoptosis in C. elegans.
@en
Depletion of the cap-associate ...... mline apoptosis in C. elegans.
@nl
prefLabel
Depletion of the cap-associate ...... mline apoptosis in C. elegans.
@ast
Depletion of the cap-associate ...... mline apoptosis in C. elegans.
@en
Depletion of the cap-associate ...... mline apoptosis in C. elegans.
@nl
P2093
P2860
P356
P1476
Depletion of the cap-associate ...... mline apoptosis in C. elegans.
@en
P2093
B D Keiper
M A Richardson
V Contreras
P2860
P2888
P304
P356
10.1038/CDD.2008.46
P577
2008-05-02T00:00:00Z