Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1. - Test2 - elhamkhani - TriplyDB

Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1.

Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1.

http://www.wikidata.org/entity/Q34777247

about

The role of epigenetics in the pathology of diabetic complications Epigenetics: a molecular link between environmental factors and type 2 diabetes Dopamine-prolactin pathway potentially contributes to the schizophrenia and type 2 diabetes comorbidity Recent progress in genetic and epigenetic research on type 2 diabetes Early Life Nutrition and Energy Balance Disorders in Offspring in Later Life Epigenetics: the missing link to understanding β-cell dysfunction in the pathogenesis of type 2 diabetes Nutrition, epigenetics, and metabolic syndrome Mammalian Non-CpG Methylation: Stem Cells and Beyond Developmental origins of obesity and type 2 diabetes: molecular aspects and role of chemicals Translational implications of the β-cell epigenome in diabetes mellitus A sustained dietary change increases epigenetic variation in isogenic mice Natural history of β-cell adaptation and failure in type 2 diabetes Mutations in Mll2, an H3K4 methyltransferase, result in insulin resistance and impaired glucose tolerance in mice Maternal protein restriction elevates cholesterol in adult rat offspring due to repressive changes in histone modifications at the cholesterol 7alpha-hydroxylase promoter Developmental and Transmittable Origins of Obesity-Associated Health Disorders.Early life nutrition, epigenetics and programming of later life disease Persistent apparent pancreatic β-cell defects in premenarchal PCOS relatives.Early developmental conditioning of later health and disease: physiology or pathophysiology?Early childhood growth failure and the developmental origins of adult disease: do enteric infections and malnutrition increase risk for the metabolic syndrome?Exercise prevents maternal high-fat diet-induced hypermethylation of the Pgc-1α gene and age-dependent metabolic dysfunction in the offspring.Child health, developmental plasticity, and epigenetic programming Non-referenced genome assembly from epigenomic short-read data 11p15 DNA-methylation analysis in monozygotic twins with discordant intrauterine development due to severe twin-to-twin transfusion syndrome Regulation of homocysteine metabolism and methylation in human and mouse tissues β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment.36 h fasting of young men influences adipose tissue DNA methylation of LEP and ADIPOQ in a birth weight-dependent manner.Increased DNA methylation and decreased expression of PDX-1 in pancreatic islets from patients with type 2 diabetes.Metabolic syndrome: from epidemiology to systems biology.Intrauterine Growth Retardation - A Developmental Model of Type 2 Diabetes.Developmental origins of health and disease: reducing the burden of chronic disease in the next generation.Epigenetic mechanisms in the development of type 2 diabetes.Insulin resistance is not conserved in myotubes established from women with PCOS.Effects of palmitate on genome-wide mRNA expression and DNA methylation patterns in human pancreatic islets.Down-regulation of pancreatic and duodenal homeobox-1 by somatostatin receptor subtype 5: a novel mechanism for inhibition of cellular proliferation and insulin secretion by somatostatin.Prevalence of Prediabetes Risk in Offspring Born to Mothers with Hyperandrogenism The Missing lnc(RNA) between the pancreatic β-cell and diabetes Experimental intrauterine growth restriction induces alterations in DNA methylation and gene expression in pancreatic islets of rats.Gene-Diet Interactions in Type 2 Diabetes: The Chicken and Egg Debate Detection of type 2 diabetes related modules and genes based on epigenetic networks Glial cell line-derived neurotrophic factor enhances neurogenin3 gene expression and beta-cell proliferation in the developing mouse pancreas.

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P2860

Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1.

http://www.wikidata.org/entity/Q34777247

description

2008 nî lūn-bûn

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2008 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2008 թվականի հունիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Development of type 2 diabetes ...... epigenetic silencing of Pdx1.

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Development of type 2 diabetes ...... epigenetic silencing of Pdx1.

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Development of type 2 diabetes ...... epigenetic silencing of Pdx1.

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Development of type 2 diabetes ...... epigenetic silencing of Pdx1.

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Development of type 2 diabetes ...... epigenetic silencing of Pdx1.

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Development of type 2 diabetes ...... epigenetic silencing of Pdx1.

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Development of type 2 diabetes ...... epigenetic silencing of Pdx1.

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Development of type 2 diabetes ...... epigenetic silencing of Pdx1.

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Development of type 2 diabetes ...... epigenetic silencing of Pdx1.

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Development of type 2 diabetes ...... epigenetic silencing of Pdx1.

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P2093

Doris A Stoffers

http://www.w3.org/2001/XMLSchema#string

Jun H Park

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Rebecca A Simmons

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Robert D Nicholls

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P2860

SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence

The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells

Cross-talk between histone modifications in response to histone deacetylase inhibitors: MLL4 links histone H3 acetylation and histone H3K4 methylation

DNA methyltransferase Dnmt1 associates with histone deacetylase activity

Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage

Pancreas duodenum homeobox-1 regulates pancreas development during embryogenesis and islet cell function in adulthood

The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3

MicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulin-producing cells

Conserved transcriptional regulatory domains of the pdx-1 gene

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6

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118

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18464933

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type-2 diabetes

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2373422

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