Evidence for increased exposure of the Notch1 metalloprotease cleavage site upon conversion to an activated conformation
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TspanC8 tetraspanins regulate ADAM10/Kuzbanian trafficking and promote Notch activation in flies and mammalsHydrogen/deuterium exchange mass spectrometry applied to IL-23 interaction characteristics: potential impact for therapeuticsForce-induced unfolding simulations of the human Notch1 negative regulatory region: possible roles of the heterodimerization domain in mechanosensingNotch ligand endocytosis: mechanistic basis of signaling activityHydrogen exchange mass spectrometry: are we out of the quicksand?Direct observation of proteolytic cleavage at the S2 site upon forced unfolding of the Notch negative regulatory regionConsiderations in the analysis of hydrogen exchange mass spectrometry data.Mutational analysis of the Notch2 negative regulatory region identifies key structural elements for mechanical stability.Notch: architect, landscaper, and guardian of the intestine.Enhanced Notch activation is advantageous but not essential for T cell lymphomagenesis in Id1 transgenic miceNotch inhibitors for cancer treatment.Generation of anti-Notch antibodies and their application in blocking Notch signalling in neural stem cells.The influence of adnectin binding on the extracellular domain of epidermal growth factor receptor.Notch1 Autoactivation via Transcriptional Regulation of Furin, Which Sustains Notch1 Signaling by Processing Notch1-Activating Proteases ADAM10 and Membrane Type 1 Matrix MetalloproteinaseActive-site inhibitors modulate the dynamic properties of human monoacylglycerol lipase: a hydrogen exchange mass spectrometry studyMembrane tethered delta activates notch and reveals a role for spatio-mechanical regulation of the signaling pathway.Asymmetric cell division in the Drosophila bristle lineage: from the polarization of sensory organ precursor cells to Notch-mediated binary fate decision.The complex role of NOTCH receptors and their ligands in the development of hepatoblastoma, cholangiocarcinoma and hepatocellular carcinoma.Human NOTCH2 Is Resistant to Ligand-independent Activation by Metalloprotease Adam17.Computational methods and challenges in hydrogen/deuterium exchange mass spectrometry.Methods to investigate the structure and connectivity of the nervous system.Functional analysis of the NHR2 domain indicates that oligomerization of Neuralized regulates ubiquitination and endocytosis of Delta during Notch signaling.Insights into Notch3 activation and inhibition mediated by antibodies directed against its negative regulatory region.Monitoring cell-cell contacts in vivo in transgenic animals.Furin promotes dendritic morphogenesis and learning and memory in transgenic mice.Cell Polarity and Notch Signaling: Linked by the E3 Ubiquitin Ligase Neuralized?
P2860
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P2860
Evidence for increased exposure of the Notch1 metalloprotease cleavage site upon conversion to an activated conformation
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Evidence for increased exposur ...... n to an activated conformation
@ast
Evidence for increased exposur ...... n to an activated conformation
@en
Evidence for increased exposur ...... n to an activated conformation
@nl
type
label
Evidence for increased exposur ...... n to an activated conformation
@ast
Evidence for increased exposur ...... n to an activated conformation
@en
Evidence for increased exposur ...... n to an activated conformation
@nl
prefLabel
Evidence for increased exposur ...... n to an activated conformation
@ast
Evidence for increased exposur ...... n to an activated conformation
@en
Evidence for increased exposur ...... n to an activated conformation
@nl
P2093
P2860
P1433
P1476
Evidence for increased exposur ...... n to an activated conformation
@en
P2093
Jon C Aster
Kittichoat Tiyanont
Miguel Aste-Amezaga
Stephen C Blacklow
Thomas E Wales
P2860
P304
P356
10.1016/J.STR.2011.01.016
P577
2011-04-01T00:00:00Z