Optimizing non-natural protein function with directed evolution.
about
Directed evolution of bright mutants of an oxygen-independent flavin-binding fluorescent protein from Pseudomonas putidaConsensus protein designEngineering a model protein cavity to catalyze the Kemp eliminationAzurin as a Protein Scaffold for a Low-coordinate Nonheme Iron Site with a Small-molecule Binding PocketStructural Insights into the Recovery of Aldolase Activity inN-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with γ-Thialysine by Using a Chemical Mutagenesis StrategyA Single Mutation in a Regulatory Protein Produces Evolvable Allosterically Regulated Catalyst of Nonnatural ReactionComputational design of ligand-binding proteins with high affinity and selectivityEnhanced enantioselectivity of a carboxyl esterase from Rhodobacter sphaeroides by directed evolutionAdvances in the directed evolution of proteins.Reshaping an enzyme binding pocket for enhanced and inverted stereoselectivity: use of smallest amino acid alphabets in directed evolutionBridging the gap: a roadmap to breaking the biological design barrierBacteriophages use an expanded genetic code on evolutionary paths to higher fitnessBiocatalyst development by directed evolutionCoupling Protein Side-Chain and Backbone Flexibility Improves the Re-design of Protein-Ligand SpecificityControlled Orientation of Active Sites in a Nanostructured Multienzyme Complex.Conformational plasticity surrounding the active site of NADH oxidase from Thermus thermophilus.Elementary tetrahelical protein design for diverse oxidoreductase functions.Directed evolution as a powerful synthetic biology tool.Rational engineering of enzyme allosteric regulation through sequence evolution analysis.Evolutionary biochemistry: revealing the historical and physical causes of protein properties.Bioengineered probes for molecular magnetic resonance imaging in the nervous system.Evolution of Metallo-β-lactamases: Trends Revealed by Natural Diversity and in vitro EvolutionPeptide aptamers: development and applications.Directed evolution by using iterative saturation mutagenesis based on multiresidue sites.Patch cloning method for multiple site-directed and saturation mutagenesis.Development of organophosphate hydrolase activity in a bacterial homolog of human cholinesteraseCovalent Anchor Positions Play an Important Role in Tuning Catalytic Properties of a Rationally Designed MnSalen-containing MetalloenzymeDepletion of T cell epitopes in lysostaphin mitigates anti-drug antibody response and enhances antibacterial efficacy in vivo.Mutations in adenine-binding pockets enhance catalytic properties of NAD(P)H-dependent enzymes.Extending enzyme molecular recognition with an expanded amino acid alphabet.Casting epPCR (cepPCR): A simple random mutagenesis method to generate high quality mutant libraries.Combinatorial evolution of site- and enantioselective catalysts for polyene epoxidationRelated (βα)8-barrel proteins in histidine and tryptophan biosynthesis: a paradigm to study enzyme evolution.Catalytic, mild, and selective oxyfunctionalization of linear alkanes: current challenges.Computational enzyme design.Protein engineering for metabolic engineering: current and next-generation tools.Rational heme protein design: all roads lead to Rome.Cell-free synthetic biology for in vitro prototype engineering.Molecular engineering of industrial enzymes: recent advances and future prospects.Metalloenzyme design and engineering through strategic modifications of native protein scaffolds.
P2860
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P2860
Optimizing non-natural protein function with directed evolution.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Optimizing non-natural protein function with directed evolution.
@ast
Optimizing non-natural protein function with directed evolution.
@en
Optimizing non-natural protein function with directed evolution.
@nl
type
label
Optimizing non-natural protein function with directed evolution.
@ast
Optimizing non-natural protein function with directed evolution.
@en
Optimizing non-natural protein function with directed evolution.
@nl
prefLabel
Optimizing non-natural protein function with directed evolution.
@ast
Optimizing non-natural protein function with directed evolution.
@en
Optimizing non-natural protein function with directed evolution.
@nl
P2860
P1476
Optimizing non-natural protein function with directed evolution.
@en
P2093
Eric M Brustad
P2860
P304
P356
10.1016/J.CBPA.2010.11.020
P577
2010-12-23T00:00:00Z