Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer. - Test2 - elhamkhani - TriplyDB

Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.

Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.

http://www.wikidata.org/entity/Q34897761

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The histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3 Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targeting Epigenetic regulation by histone demethylases in hypoxia High-throughput screening to identify inhibitors of lysine demethylases Histone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and prevention KDM5 interacts with Foxo to modulate cellular levels of oxidative stress 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors Histone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genes Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance The histone demethylase dKDM5/LID interacts with the SIN3 histone deacetylase complex and shares functional similarities with SIN3.Distribution and prediction of catalytic domains in 2-oxoglutarate dependent dioxygenases.Folate deficiency facilitates recruitment of upstream binding factor to hot spots of DNA double-strand breaks of rRNA genes and promotes its transcription Histone demethylase RBP2 is critical for breast cancer progression and metastasis.H3K4 demethylase activities repress proliferative and postmitotic aging.Application of MassSQUIRM for quantitative measurements of lysine demethylase activity.Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1 ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate.Histone ubiquitination and deubiquitination in transcription, DNA damage response, and cancer.Proteotranscriptomic Profiling of 231-BR Breast Cancer Cells: Identification of Potential Biomarkers and Therapeutic Targets for Brain Metastasis.Epigenetic mechanisms in commonly occurring cancers.Mutations in the KDM5C ARID Domain and Their Plausible Association with Syndromic Claes-Jensen-Type Disease.Escape from Mitotic Arrest: An Unexpected Connection Between Microtubule Dynamics and Epigenetic Regulation of Centromeric Chromatin in Schizosaccharomyces pombe.Investigation of Histone Lysine-Specific Demethylase 5D KDM5D) Isoform Expression in Prostate Cancer Cell Lines: a System Approach Transcriptional Regulation of JARID1B/KDM5B Histone Demethylase by Ikaros, Histone Deacetylase 1 (HDAC1), and Casein Kinase 2 (CK2) in B-cell Acute Lymphoblastic Leukemia.Depletion of histone demethylase KDM5B inhibits cell proliferation of hepatocellular carcinoma by regulation of cell cycle checkpoint proteins p15 and p27.Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen.Suppression of Enhancer Overactivation by a RACK7-Histone Demethylase Complex Epigenetic regulation in adult stem cells and cancers.An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells KDM5 lysine demethylases are involved in maintenance of 3'UTR length.The methylation landscape of tumour metastasis.Histone H3K4 trimethylation: dynamic interplay with pre-mRNA splicing.Targeting epigenetic regulators for cancer therapy: modulation of bromodomain proteins, methyltransferases, demethylases, and microRNAs.Effect of histone deacetylase on prostate carcinoma.Pyrido[3,4-d]pyrimidin-4(3H)-one metabolism mediated by aldehyde oxidase is blocked by C2-substitution RBP2 induces stem-like cancer cells by promoting EMT and is a prognostic marker for renal cell carcinoma.The Histone Demethylase KDM5 Activates Gene Expression by Recognizing Chromatin Context through Its PHD Reader Motif.siRNA targeting RBP2 inhibits expression, proliferation, tumorigenicity and invasion in thyroid carcinoma cells Histone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNA repair.

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Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.

http://www.wikidata.org/entity/Q34897761

description

2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.

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Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.

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Epigenetic Regulation by Lysine Demethylase 5

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type

label

Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.

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Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.

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Epigenetic Regulation by Lysine Demethylase 5

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Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.

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Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.

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Epigenetic Regulation by Lysine Demethylase 5

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Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer

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Jian Cao

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Joyce Sayegh

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Lauren P Blair

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Mike Ran Zou

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Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains

A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancer

Crystal structure of the nucleosome core particle at 2.8 A resolution

Developmental roles of the histone lysine demethylases

Retinoblastoma-binding protein 2 (Rbp2) potentiates nuclear hormone receptor-mediated transcription

Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis.

Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression

The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases

Human PLU-1 Has transcriptional repression properties and interacts with the developmental transcription factors BF-1 and PAX9

An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB

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1383-1404

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scholarly article

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10.3390/CANCERS3011383

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1

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3

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21544224

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3085456

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