RIG-I and MDA-5 detection of viral RNA-dependent RNA polymerase activity restricts positive-strand RNA virus replication
about
Alphavirus RNA synthesis and non-structural protein functionsThe interface between methyltransferase and polymerase of NS5 is essential for flavivirus replicationCombined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication.Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus-specific neutralizing antibody responseAntiviral Protection via RdRP-Mediated Stable Activation of Innate Immunity.Versatile Trans-Replication Systems for Chikungunya Virus Allow Functional Analysis and Tagging of Every Replicase Protein.New World and Old World Alphaviruses Have Evolved to Exploit Different Components of Stress Granules, FXR and G3BP Proteins, for Assembly of Viral Replication Complexes.Critical role of RIG-I and MDA5 in early and late stages of Tulane virus infection.De Novo Transcriptome Analysis Shows That SAV-3 Infection Upregulates Pattern Recognition Receptors of the Endosomal Toll-Like and RIG-I-Like Receptor Signaling Pathways in Macrophage/Dendritic Like TO-Cells.Activation of the RLR/MAVS Signaling Pathway by the L Protein of Mopeia Virus.Emerging complexity and new roles for the RIG-I-like receptors in innate antiviral immunity.NOD1 Participates in the Innate Immune Response Triggered by Hepatitis C Virus PolymeraseBoth RIG-I and MDA5 detect alphavirus replication in concentration-dependent mode.A Novel Mechanism Underlying the Innate Immune Response Induction upon Viral-Dependent Replication of Host Cell mRNA: A Mistake of +sRNA Viruses' Replicases.Discrimination of Self and Non-Self Ribonucleic Acids.Transmembrane Domains of NS2B Contribute to both Viral RNA Replication and Particle Formation in Japanese Encephalitis Virus.The microRNA miR-485 targets host and influenza virus transcripts to regulate antiviral immunity and restrict viral replication.Emerging Alphaviruses are Sensitive to Cellular States Induced by a Novel Small Molecule Agonist of the STING Pathway.A Chikungunya virus trans-replicase system reveals the importance of delayed non-structural polyprotein processing for efficient replication complex formation in mosquito cells.DDX5 RNA Helicases: Emerging Roles in Viral Infection.DNA-launched RNA replicon vaccines induce potent anti-Ebolavirus immune responses that can be further improved by a recombinant MVA boostPotent therapeutic efficacy of an alphavirus replicon DNA vaccine expressing human papilloma virus E6 and E7 antigensDecreased Virulence of Ross River Virus Harboring a Mutation in the First Cleavage Site of Nonstructural Polyprotein Is Caused by a Novel Mechanism Leading to Increased Production of Interferon-Inducing RNAs
P2860
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P2860
RIG-I and MDA-5 detection of viral RNA-dependent RNA polymerase activity restricts positive-strand RNA virus replication
description
2013 nî lūn-bûn
@nan
2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
RIG-I and MDA-5 detection of v ...... e-strand RNA virus replication
@ast
RIG-I and MDA-5 detection of v ...... e-strand RNA virus replication
@en
RIG-I and MDA-5 detection of v ...... e-strand RNA virus replication
@nl
type
label
RIG-I and MDA-5 detection of v ...... e-strand RNA virus replication
@ast
RIG-I and MDA-5 detection of v ...... e-strand RNA virus replication
@en
RIG-I and MDA-5 detection of v ...... e-strand RNA virus replication
@nl
prefLabel
RIG-I and MDA-5 detection of v ...... e-strand RNA virus replication
@ast
RIG-I and MDA-5 detection of v ...... e-strand RNA virus replication
@en
RIG-I and MDA-5 detection of v ...... e-strand RNA virus replication
@nl
P2093
P2860
P50
P1433
P1476
RIG-I and MDA-5 detection of v ...... e-strand RNA virus replication
@en
P2093
Andres Männik
Kaja Kiiver
Mart Ustav
Rein Sikut
Tarmo Mölder
Urve Toots
P2860
P304
P356
10.1371/JOURNAL.PPAT.1003610
P577
2013-09-05T00:00:00Z