Hyperactivity of newborn Pten knock-out neurons results from increased excitatory synaptic drive
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The parvalbumin/somatostatin ratio is increased in Pten mutant mice and by human PTEN ASD alleles.Hyperactive mTOR signals in the proopiomelanocortin-expressing hippocampal neurons cause age-dependent epilepsy and premature death in miceSelective neuronal PTEN deletion: can we take the brakes off of growth without losing control?MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders.MiR-338-3p regulates neuronal maturation and suppresses glioblastoma proliferation.Monogenic mouse models of autism spectrum disorders: Common mechanisms and missing links.A Retroviral CRISPR-Cas9 System for Cellular Autism-Associated Phenotype Discovery in Developing Neurons.Dysfunctional mTORC1 Signaling: A Convergent Mechanism between Syndromic and Nonsyndromic Forms of Autism Spectrum Disorder?PTEN loss increases the connectivity of fast synaptic motifs and functional connectivity in a developing hippocampal network.Pediatric Traumatic Brain Injury and Autism: Elucidating Shared Mechanisms.Autism, epilepsy, and synaptopathies: a not rare association.Autism spectrum disorder-associated genes and the development of dentate granule cells.Parallel processing of afferent olfactory sensory information.Designing, Packaging, and Delivery of High Titer CRISPR Retro and Lentiviruses via Stereotaxic Injection.Long-term consequences of conditional genetic deletion of PTEN in the sensorimotor cortex of neonatal mice.Rapamycin prevents, but does not reverse, aberrant migration in Pten knockout neurons.Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons.Adult-born neurons modify excitatory synaptic transmission to existing neurons.Disrupted hippocampal network physiology following PTEN deletion from newborn dentate granule cells.Cellular Phenotypes in Human iPSC-Derived Neurons from a Genetic Model of Autism Spectrum Disorder.PTEN deletion increases hippocampal granule cell excitability in male and female mice.Nuclear Excluded Autism-Associated Phosphatase and Tensin Homolog Mutations Dysregulate Neuronal Growth.Environmental Enrichment Ameliorates Neonatal Sevoflurane Exposure-Induced Cognitive and Synaptic Plasticity Impairments.Neuronal PTEN deletion in adult cortical neurons triggers progressive growth of cell bodies, dendrites, and axons.Potassium Channel Gain of Function in Epilepsy: An Unresolved Paradox.Contributions of Adult-Generated Granule Cells to Hippocampal Pathology in Temporal Lobe Epilepsy: A Neuronal BestiaryThe role of hippocampal adult neurogenesis in methamphetamine addiction
P2860
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P2860
Hyperactivity of newborn Pten knock-out neurons results from increased excitatory synaptic drive
description
2015 nî lūn-bûn
@nan
2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Hyperactivity of newborn Pten ...... ased excitatory synaptic drive
@ast
Hyperactivity of newborn Pten ...... ased excitatory synaptic drive
@en
Hyperactivity of newborn Pten ...... ased excitatory synaptic drive
@nl
type
label
Hyperactivity of newborn Pten ...... ased excitatory synaptic drive
@ast
Hyperactivity of newborn Pten ...... ased excitatory synaptic drive
@en
Hyperactivity of newborn Pten ...... ased excitatory synaptic drive
@nl
prefLabel
Hyperactivity of newborn Pten ...... ased excitatory synaptic drive
@ast
Hyperactivity of newborn Pten ...... ased excitatory synaptic drive
@en
Hyperactivity of newborn Pten ...... ased excitatory synaptic drive
@nl
P2860
P50
P1476
Hyperactivity of newborn Pten ...... ased excitatory synaptic drive
@en
P2093
P2860
P304
P356
10.1523/JNEUROSCI.3144-14.2015
P407
P577
2015-01-01T00:00:00Z