Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos.
about
The therapeutic potential of genome editing for β-thalassemiaNovel impact of the DNMT3A R882H mutation on GSH metabolism in a K562 cell model established by TALENs.Development of an intein-mediated split-Cas9 system for gene therapyEfficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotesFunctional interrogation of non-coding DNA through CRISPR genome editing.Large genomic fragment deletion and functional gene cassette knock-in via Cas9 protein mediated genome editing in one-cell rodent embryos.The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.An alternative strategy for targeted gene replacement in plants using a dual-sgRNA/Cas9 design.Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function.TALEN-mediated genome-editing approaches in the liverwort Marchantia polymorpha yield high efficiencies for targeted mutagenesis.Road to the future of systems biotechnology: CRISPR-Cas-mediated metabolic engineering for recombinant protein production.To CRISPR and beyond: the evolution of genome editing in stem cells.CRISPR/Cas9-Mediated Genome Editing as a Therapeutic Approach for Leber Congenital Amaurosis 10.GATA2/3-TFAP2A/C transcription factor network couples human pluripotent stem cell differentiation to trophectoderm with repression of pluripotency.Enhanced genome editing in mammalian cells with a modified dual-fluorescent surrogate system.The Application of CRISPR/Cas9 for the Treatment of Retinal Diseases.The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans
P2860
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P2860
Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos.
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Creation of targeted genomic d ...... irs in one-cell mouse embryos.
@ast
Creation of targeted genomic d ...... irs in one-cell mouse embryos.
@en
type
label
Creation of targeted genomic d ...... irs in one-cell mouse embryos.
@ast
Creation of targeted genomic d ...... irs in one-cell mouse embryos.
@en
prefLabel
Creation of targeted genomic d ...... irs in one-cell mouse embryos.
@ast
Creation of targeted genomic d ...... irs in one-cell mouse embryos.
@en
P2093
P2860
P1433
P1476
Creation of targeted genomic d ...... airs in one-cell mouse embryos
@en
P2093
Benedikt Wefers
Bernhard Röttig
Christina Brandl
Oskar Ortiz
Wolfgang Wurst
P2860
P356
10.1016/J.FOB.2014.11.009
P50
P577
2014-12-03T00:00:00Z