Multifaceted activities of type I interferon are revealed by a receptor antagonist. - Test2 - elhamkhani - TriplyDB

Multifaceted activities of type I interferon are revealed by a receptor antagonist.

Multifaceted activities of type I interferon are revealed by a receptor antagonist.

http://www.wikidata.org/entity/Q35031568

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Harnessing Mechanistic Knowledge on Beneficial Versus Deleterious IFN-I Effects to Design Innovative Immunotherapies Targeting Cytokine Activity to Specific Cell Types Insights into cytokine-receptor interactions from cytokine engineering Receptor dimerization dynamics as a regulatory valve for plasticity of type I interferon signaling Expansion of amphibian intronless interferons revises the paradigm for interferon evolution and functional diversity Interferons and viruses: an evolutionary arms race of molecular interactions Cytokine Activation by Antibody Fragments Targeted to Cytokine-Receptor Signaling Complexes.Extraordinary effects of unnatural pairings Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression.New insights into type I interferon and the immunopathogenesis of persistent viral infections.Interleukin-2 activity can be fine tuned with engineered receptor signaling clamps.Synthekines are surrogate cytokine and growth factor agonists that compel signaling through non-natural receptor dimers.Design and evaluation of novel interferon lambda analogs with enhanced antiviral activity and improved drug attributes.Differential Type I Interferon Signaling Is a Master Regulator of Susceptibility to Postinfluenza Bacterial Superinfection.Spatiotemporal control of interferon-induced JAK/STAT signalling and gene transcription by the retromer complex.Blocking type I interferon signaling enhances T cell recovery and reduces HIV-1 reservoirs.Type I Interferon Signaling Is Decoupled from Specific Receptor Orientation through Lenient Requirements of the Transmembrane Domain.IFNAR2-dependent gene expression profile induced by IFN-α in Pteropus alecto bat cells and impact of IFNAR2 knockout on virus infection.A hot spot on interferon α/β receptor subunit 1 (IFNAR1) underpins its interaction with interferon-β and dictates signaling.Fine Tuning of a Type 1 Interferon Antagonist.Human pDCs display sex-specific differences in type I interferon subtypes and interferon α/β receptor expression.The molecular basis for differential type I interferon signaling.Type I interferons suppress viral replication but contribute to T cell depletion and dysfunction during chronic HIV-1 infection.The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity.Dynamic Modulation of Binding Affinity as a Mechanism for Regulating Interferon Signaling.Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling.Mapping Determinants of Cytokine Signaling via Protein Engineering Type I IFN signaling blockade by a PASylated antagonist during chronic SIV infection suppresses specific inflammatory pathways but does not alter T cell activation or virus replication

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P2860

Multifaceted activities of type I interferon are revealed by a receptor antagonist.

http://www.wikidata.org/entity/Q35031568

description

2014 nî lūn-bûn

@nan

2014 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2014年の論文

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2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Multifaceted activities of type I interferon are revealed by a receptor antagonist.

@ast

Multifaceted activities of type I interferon are revealed by a receptor antagonist.

@en

type

label

Multifaceted activities of type I interferon are revealed by a receptor antagonist.

@ast

Multifaceted activities of type I interferon are revealed by a receptor antagonist.

@en

prefLabel

Multifaceted activities of type I interferon are revealed by a receptor antagonist.

@ast

Multifaceted activities of type I interferon are revealed by a receptor antagonist.

@en

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SCISIGNAL.2004998

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Science Signaling

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Multifaceted activities of type I interferon are revealed by a receptor antagonist.

@en

P2093

Alberto Giovanni Busetto

http://www.w3.org/2001/XMLSchema#string

Charles M Rice

http://www.w3.org/2001/XMLSchema#string

Doron Levin

http://www.w3.org/2001/XMLSchema#string

Ganit Yarden

http://www.w3.org/2001/XMLSchema#string

Gideon Schreiber

http://www.w3.org/2001/XMLSchema#string

Hans-Heinrich Hoffmann

http://www.w3.org/2001/XMLSchema#string

Nanaocha Sharma

http://www.w3.org/2001/XMLSchema#string

Ohad Manor

http://www.w3.org/2001/XMLSchema#string

William M Schneider

http://www.w3.org/2001/XMLSchema#string

P2860

Biological activity of interleukins-28 and -29: comparison with type I interferons

IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex

MX2 is an interferon-induced inhibitor of HIV-1 infection

Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes

A diverse range of gene products are effectors of the type I interferon antiviral response

INTERFEROME: the database of interferon regulated genes

Regulation of type I interferon responses

Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras

Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system

Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons

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10.1126/SCISIGNAL.2004998

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327

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7

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4311876

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