Inhibition of cdk9 during herpes simplex virus 1 infection impedes viral transcription - Test2 - elhamkhani - TriplyDB

Inhibition of cdk9 during herpes simplex virus 1 infection impedes viral transcription

Inhibition of cdk9 during herpes simplex virus 1 infection impedes viral transcription

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An Epigenetic Compound Library Screen Identifies BET Inhibitors That Promote HSV-1 and -2 Replication by Bridging P-TEFb to Viral Gene Promoters through BRD4 CDK9 inhibitor FIT-039 prevents replication of multiple DNA viruses.Human cytomegalovirus pUL79 is an elongation factor of RNA polymerase II for viral gene transcription.Multiple Lytic Origins of Replication Are Required for Optimal Gammaherpesvirus Fitness In Vitro and In Vivo CTCF interacts with the lytic HSV-1 genome to promote viral transcription.Transcriptional Elongation of HSV Immediate Early Genes by the Super Elongation Complex Drives Lytic Infection and Reactivation from Latency.Synthesis, structure-activity relationship studies and biological evaluation of novel 2,5-disubstituted indole derivatives as anticancer agents.Potential Use of Flavopiridol in Treatment of Chronic Diseases.A Herpesviral Immediate Early Protein Promotes Transcription Elongation of Viral Transcripts.HSV-1-induced disruption of transcription termination resembles a cellular stress response but selectively increases chromatin accessibility downstream of genes.

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P2860

Inhibition of cdk9 during herpes simplex virus 1 infection impedes viral transcription

http://www.wikidata.org/entity/Q35036881

description

2013 nî lūn-bûn

@nan

2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Inhibition of cdk9 during herpes simplex virus 1 infection impedes viral transcription

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Inhibition of cdk9 during herpes simplex virus 1 infection impedes viral transcription

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Inhibition of cdk9 during herpes simplex virus 1 infection impedes viral transcription

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Inhibition of cdk9 during herpes simplex virus 1 infection impedes viral transcription

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Inhibition of cdk9 during herpes simplex virus 1 infection impedes viral transcription

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JOURNAL.PONE.0079007

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Inhibition of cdk9 during herpes simplex virus 1 infection impedes viral transcription

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Mark Ou

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P2860

Suppression of NF-kappaB-dependent gene expression by a hexamethylene bisacetamide-inducible protein HEXIM1 in human vascular smooth muscle cells

Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA

The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation

DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

ICP27 interacts with the RNA export factor Aly/REF to direct herpes simplex virus type 1 intronless mRNAs to the TAP export pathway.

Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor

Capping, splicing, and 3' processing are independently stimulated by RNA polymerase II: different functions for different segments of the CTD

7SK snRNA: a noncoding RNA that plays a major role in regulating eukaryotic transcription

A new paradigm in eukaryotic biology: HIV Tat and the control of transcriptional elongation

Halogen bonds form the basis for selective P-TEFb inhibition by DRB

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e79007

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scholarly article

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10.1371/JOURNAL.PONE.0079007

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10

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Rozanne M Sandri-Goldin

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2013-10-18T00:00:00Z

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258350910

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