Neurokinin NK1 and NK3 receptors as targets for drugs to treat gastrointestinal motility disorders and pain.
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Management of Chemotherapy Induced Nausea and Vomiting in Patients on Multiday Cisplatin Based Combination ChemotherapyUpregulation of the transient receptor potential ankyrin 1 ion channel in the inflamed human and mouse colon and its protective rolesAn Endogenous Tachykinergic NK2/NK3 Receptor Cascade System Controlling the Release of Serotonin from Colonic MucosaFunctional GI disorders: from animal models to drug development.Review article: current and emerging therapies for functional dyspepsia.Effect of the NK(3) receptor antagonist, talnetant, on rectal sensory function and compliance in healthy humans.Maropitant prevented vomiting but not gastroesophageal reflux in anesthetized dogs premedicated with acepromazine-hydromorphone.The role of experimental models in developing new treatments for irritable bowel syndrome.Quantification of central substance P receptor occupancy by aprepitant using small animal positron emission tomography.A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response.Activation of tachykinin, neurokinin 3 receptors affects chromatin structure and gene expression by means of histone acetylationEmerging drugs for irritable bowel syndrome.Review article: modulation of the brain-gut axis as a therapeutic approach in gastrointestinal disease.Novel therapeutic approaches in IBS.A review of irritable bowel syndrome and an update on therapeutic approaches.The role of vagal neurocircuits in the regulation of nausea and vomiting.Rolapitant (Varubi): A Substance P/Neurokinin-1 Receptor Antagonist for the Prevention of Chemotherapy-Induced Nausea and Vomiting.Existing and emerging therapies for irritable bowel syndrome.Molecular imaging probes derived from natural peptides.Contractile effect of tachykinins on rabbit small intestine.Differential role of tachykinin NK3 receptors on cholinergic excitatory neurotransmission in the mouse stomach and small intestine.Aprepitant has Mixed Effects on Nausea and Reduces Other Symptoms in Patients With Gastroparesis and Related Disorders.Modulation of peristalsis by NK3 receptor antagonism in guinea-pig isolated ileum is revealed as intraluminal pressure is raised.A History of Drug Discovery for Treatment of Nausea and Vomiting and the Implications for Future Research
P2860
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P2860
Neurokinin NK1 and NK3 receptors as targets for drugs to treat gastrointestinal motility disorders and pain.
description
2004 nî lūn-bûn
@nan
2004 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մարտին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Neurokinin NK1 and NK3 recepto ...... l motility disorders and pain.
@en
type
label
Neurokinin NK1 and NK3 recepto ...... l motility disorders and pain.
@en
prefLabel
Neurokinin NK1 and NK3 recepto ...... l motility disorders and pain.
@en
P2860
P356
P1476
Neurokinin NK1 and NK3 recepto ...... l motility disorders and pain.
@en
P2093
Gareth J Sanger
P2860
P304
P356
10.1038/SJ.BJP.0705742
P407
P577
2004-03-15T00:00:00Z