Adapting the γ-H2AX assay for automated processing in human lymphocytes. 1. Technological aspects. - Test2 - elhamkhani - TriplyDB

Adapting the γ-H2AX assay for automated processing in human lymphocytes. 1. Technological aspects.

Adapting the γ-H2AX assay for automated processing in human lymphocytes. 1. Technological aspects.

http://www.wikidata.org/entity/Q35064509

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Deoxyribonucleic acid damage-associated biomarkers of ionising radiation: current status and future relevance for radiology and radiotherapy Use of the γ-H2AX assay to monitor DNA damage and repair in translational cancer research Establishment of a γ-H2AX foci-based assay to determine biological dose of radon to red bone marrow in rats Fast image analysis for the micronucleus assay in a fully automated high-throughput biodosimetry system Advances in a framework to compare bio-dosimetry methods for triage in large-scale radiation events Next generation platforms for high-throughput biodosimetry.Development of a metabolomic radiation signature in urine from patients undergoing total body irradiation The RABiT: a rapid automated biodosimetry tool for radiological triage. II. Technological developments RABiT-II: Implementation of a High-Throughput Micronucleus Biodosimetry Assay on Commercial Biotech Robotic Systems γ-H2AX foci are increased in lymphocytes in vivo in young children 1 h after very low-dose X-irradiation: a pilot study.A Rapid, Quantitative Method to Characterize The Human Lymphocyte Concentration for Automated High-Throughput Radiation Biodosimetry.Recent developments in the use of γ-H2AX as a quantitative DNA double-strand break biomarker.High throughput measurement of γH2AX DSB repair kinetics in a healthy human population Infrastructure to support ultra high throughput biodosimetry screening after a radiological event A Framework for Comparative Evaluation of Dosimetric Methods to Triage a Large Population Following a Radiological Event An automated imaging system for radiation biodosimetry.γ-H2AX Kinetic Profile in Mouse Lymphocytes Exposed to the Internal Emitters Cesium-137 and Strontium-90.Effect of dose rate on residual γ-H2AX levels and frequency of micronuclei in X-irradiated mouse lymphocytes γ-H2AX and other histone post-translational modifications in the clinic.Development of a High-Throughput and Miniaturized Cytokinesis-Block Micronucleus Assay for Use as a Biological Dosimetry Population Triage Tool.In vitro RABiT measurement of dose rate effects on radiation induction of micronuclei in human peripheral blood lymphocytes Evaluation of the gamma-H2AX assay for radiation biodosimetry in a swine model DNA damage focus analysis in blood samples of minipigs reveals acute partial body irradiation.The RABiT: high-throughput technology for assessing global DSB repair.Overview of the principles and practice of biodosimetry.Gamma-H2AX biodosimetry for use in large scale radiation incidents: comparison of a rapid '96 well lyse/fix' protocol with a routine method.Differences in quantification of DNA double-strand breaks assessed by 53BP1/γH2AX focus formation assays and the comet assay in mammalian cells treated with irradiation and N-acetyl-L-cysteine Evaluating the Special Needs of The Military for Radiation Biodosimetry for Tactical Warfare Against Deployed Troops: Comparing Military to Civilian Needs for Biodosimetry Methods THE DECADE OF THE RABiT (2005-15).Liquid Handling Optimization in High-Throughput Biodosimetry Tool.Fully automated analysis of chemically induced γH2AX foci in human peripheral blood mononuclear cells by indirect immunofluorescence.Candidate gene biodosimetry markers of exposure to external ionizing radiation in human blood: A systematic review.Candidate protein markers for radiation biodosimetry in the hematopoietically humanized mouse model

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Adapting the γ-H2AX assay for automated processing in human lymphocytes. 1. Technological aspects.

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2010 nî lūn-bûn

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2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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P2860

The role of double-strand break repair — insights from human genetics

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

Pathways of DNA double-strand break repair during the mammalian cell cycle

GammaH2AX and cancer

Cytometric analysis of DNA damage: phosphorylation of histone H2AX as a marker of DNA double-strand breaks (DSBs).

Ionizing radiation-dependent gamma-H2AX focus formation requires ataxia telangiectasia mutated and ataxia telangiectasia mutated and Rad3-related.

H2AX: functional roles and potential applications.

Histone H2AX in DNA damage and repair.

DNA strand break repair and human genetic disease.

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10.1667/RR2125.1

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