Decreased thickness and integrity of the macular elastic layer of Bruch's membrane correspond to the distribution of lesions associated with age-related macular degeneration. - Test2 - elhamkhani - TriplyDB

Decreased thickness and integrity of the macular elastic layer of Bruch's membrane correspond to the distribution of lesions associated with age-related macular degeneration.

Decreased thickness and integrity of the macular elastic layer of Bruch's membrane correspond to the distribution of lesions associated with age-related macular degeneration.

http://www.wikidata.org/entity/Q35083573

about

A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration The potential role of amyloid beta in the pathogenesis of age-related macular degeneration.Sublytic membrane-attack-complex (MAC) activation alters regulated rather than constitutive vascular endothelial growth factor (VEGF) secretion in retinal pigment epithelium monolayers Can Novel Treatment of Age-Related Macular Degeneration Be Developed by Better Understanding of Sorsby's Fundus Dystrophy Polypoidal Choroidal Vasculopathy in Asians Adhesion failures determine the pattern of choroidal neovascularization in the eye: a computer simulation study The lipid translocase, ABCA4: seeing is believing.Systemic complement activation in age-related macular degeneration Retinal haemodynamics in patients with age-related macular degeneration.Influence of ROBO1 and RORA on risk of age-related macular degeneration reveals genetically distinct phenotypes in disease pathophysiology A novel source of methylglyoxal and glyoxal in retina: implications for age-related macular degeneration ABCA4-associated retinal degenerations spare structure and function of the human parapapillary retina.Age-related macular degeneration--emerging pathogenetic and therapeutic concepts.Increased choroidal neovascularization following laser induction in mice lacking lysyl oxidase-like 1.Influence of age on retinochoroidal healing processes after argon photocoagulation in C57bl/6j mice.The alternative pathway is required, but not alone sufficient, for retinal pathology in mouse laser-induced choroidal neovascularization.Evidence for an inflammatory process in age-related macular degeneration gains new support.Heat treatment of retinal pigment epithelium induces production of elastic lamina components and antiangiogenic activity.Topographic and age-related changes of the retinal epithelium and Bruch's membrane of rhesus monkeys Changes in fibroblast mechanostat set point and mechanosensitivity: an adaptive response to mechanical stress in floppy eyelid syndrome Systemic human CR2-targeted complement alternative pathway inhibitor ameliorates mouse laser-induced choroidal neovascularization.Foveal localization in non-exudative AMD using scanning laser polarimetry Studying age-related macular degeneration using animal models.Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration.Multiplex analysis of age-related protein and lipid modifications in human Bruch's membrane Age-related macular degeneration: genetics and biology coming together.Treatment with 670 nm light up regulates cytochrome C oxidase expression and reduces inflammation in an age-related macular degeneration model.Race- and sex-related differences in retinal thickness and foveal pit morphology.Heparanase-1 activities in the development of laser induced choroidal neovascularization.Bruch's membrane thickness in high myopia.Increased expression of multifunctional serine protease, HTRA1, in retinal pigment epithelium induces polypoidal choroidal vasculopathy in mice.Complement, age-related macular degeneration and a vision of the future A comparison of some organizational characteristics of the mouse central retina and the human macula Age-related decline in VIP-positive parasympathetic nerve fibers in the human submacular choroid Impaired expression of thrombospondin-1 in eyes with age related macular degeneration.CNTF Gene Therapy Confers Lifelong Neuroprotection in a Mouse Model of Human Retinitis Pigmentosa Whole Exome Sequencing in Patients with the Cuticular Drusen Subtype of Age-Related Macular Degeneration A Novel Quantitative 500-MHz Acoustic Microscopy System for Ophthalmologic Tissues.Reengineering Human Bruch's Membrane Increases Rod Outer Segment Phagocytosis by Human Retinal Pigment Epithelium.Anatomy and development of the macula: specialisation and the vulnerability to macular degeneration.

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P2860

Decreased thickness and integrity of the macular elastic layer of Bruch's membrane correspond to the distribution of lesions associated with age-related macular degeneration.

http://www.wikidata.org/entity/Q35083573

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Decreased thickness and integr ...... -related macular degeneration.

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Decreased thickness and integr ...... -related macular degeneration.

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The American Journal of Pathology

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Decreased thickness and integr ...... e-related macular degeneration

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Christina I Frennesson

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David M Weingeist

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Gregory S Hageman

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Jason Keonin

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Phil J Luthert

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Rachel L Wolf

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P2860

Inflammation and Alzheimer's disease

An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration

Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with Sorsby's fundus dystrophy

Intrachoroidal neovascularization in transgenic mice overexpressing vascular endothelial growth factor in the retinal pigment epithelium

Clinicopathological correlation in exudative age-related macular degeneration: recurrent choroidal neovascularization.

Iatrogenic choroidal neovascularization.

VEGF is major stimulator in model of choroidal neovascularization.

Accumulation of cholesterol with age in human Bruch's membrane.

Predilection of the macular region to high incidence of choroidal neovascularization after intense laser photocoagulation in the monkey.

Ageing and degeneration in the macular region: a clinico-pathological study.

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241-251

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1

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166

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Ngaihang Victor Chong

Robert F. Mullins

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8099003

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15632016

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1602307

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