The potential role of amyloid beta in the pathogenesis of age-related macular degeneration.
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Therapeutic targets in age-related macular diseaseAmyloidosis in Retinal Neurodegenerative DiseasesAMD and the alternative complement pathway: genetics and functional implicationsDementia of the eye: the role of amyloid beta in retinal degenerationPhotoreceptor cell death and rescue in retinal detachment and degenerationsNLRP3 inflammasome: activation and regulation in age-related macular degenerationThe proteomics of drusenAt the interface of sensory and motor dysfunctions and Alzheimer's disease.Systemic administration of Abeta mAb reduces retinal deposition of Abeta and activated complement C3 in age-related macular degeneration mouse modelDrusen, choroidal neovascularization, and retinal pigment epithelium dysfunction in SOD1-deficient mice: a model of age-related macular degenerationTherapeutic angiogenesis by ex vivo expanded erythroid progenitor cells.The oxysterol 27-hydroxycholesterol increases β-amyloid and oxidative stress in retinal pigment epithelial cells.The complexities underlying age-related macular degeneration: could amyloid beta play an important role?Novel rodent models for macular researchRetinal ultrastructure of murine models of dry age-related macular degeneration (AMD).Differential network analyses of Alzheimer's disease identify early events in Alzheimer's disease pathologyMicroglial MAC1 receptor and PI3K are essential in mediating β-amyloid peptide-induced microglial activation and subsequent neurotoxicityIron increases APP translation and amyloid-beta production in the retina.Genetically augmenting Abeta42 levels in skeletal muscle exacerbates inclusion body myositis-like pathology and motor deficits in transgenic mice.Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration.Progress and perspectives on the role of RPE cell inflammatory responses in the development of age-related macular degeneration.SOD1 (copper/zinc superoxide dismutase) deficiency drives amyloid β protein oligomerization and memory loss in mouse model of Alzheimer diseaseCyclic intensive light exposure induces retinal lesions similar to age-related macular degeneration in APPswe/PS1 bigenic miceInhibition of development of laser-induced choroidal neovascularization with suppression of infiltration of macrophages in Smad3-null mice.Treatment of Stargardt disease with dobesilate.Differential accumulation of secreted AbetaPP metabolites in ocular fluidsNovel roles for α-crystallins in retinal function and disease.Dry age-related macular degeneration like pathology in aged 5XFAD mice: Ultrastructure and microarray analysis.β-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment.Evidence of a novel gene HERPUD1 in polypoidal choroidal vasculopathy.RAGE mediated intracellular Aβ uptake contributes to the breakdown of tight junction in retinal pigment epithelium.Activity loss is associated with cognitive decline in age-related macular degeneration.Nef exosomes isolated from the plasma of individuals with HIV-associated dementia (HAD) can induce Aβ(1-42) secretion in SH-SY5Y neural cellsUnfolding the Therapeutic Potential of Chemical Chaperones for Age-related Macular DegenerationChronic oxidative stress upregulates Drusen-related protein expression in adult human RPE stem cell-derived RPE cells: a novel culture model for dry AMD.New therapeutic targets in atrophic age-related macular degeneration.Beta-amyloid deposition and functional impairment in the retina of the APPswe/PS1DeltaE9 transgenic mouse model of Alzheimer's disease.gamma-Secretase: a multifaceted regulator of angiogenesisGlial and endothelial blood-retinal barrier responses to amyloid-beta in the neural retina of the ratVariability in depressive symptoms predicts cognitive decline in age-related macular degeneration
P2860
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P2860
The potential role of amyloid beta in the pathogenesis of age-related macular degeneration.
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
name
The potential role of amyloid ...... e-related macular degeneration
@nl
The potential role of amyloid ...... -related macular degeneration.
@ast
The potential role of amyloid ...... -related macular degeneration.
@en
The potential role of amyloid ...... -related macular degeneration.
@en-gb
type
label
The potential role of amyloid ...... e-related macular degeneration
@nl
The potential role of amyloid ...... -related macular degeneration.
@ast
The potential role of amyloid ...... -related macular degeneration.
@en
The potential role of amyloid ...... -related macular degeneration.
@en-gb
prefLabel
The potential role of amyloid ...... e-related macular degeneration
@nl
The potential role of amyloid ...... -related macular degeneration.
@ast
The potential role of amyloid ...... -related macular degeneration.
@en
The potential role of amyloid ...... -related macular degeneration.
@en-gb
P2093
P2860
P3181
P356
P1476
The potential role of amyloid ...... -related macular degeneration.
@en
P2093
Ikuo Morita
Manabu Mochizuki
Nobuhisa Iwata
Shizuko Ichinose
Takaomi C Saido
Takeshi Yoshida
Tetsuji Sato
Toshio Hisatomi
P2860
P304
P3181
P356
10.1172/JCI24635
P407
P577
2005-09-15T00:00:00Z